Pages tagged with "RCT"

987 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• Overview of Vitamin D Meta-analysis and RCT for Caucasians
• Randomized Controlled Trials in VitaminDWiki - many studies
• Vitamin D is needed before many surgeries – many studies and RCTs
• Observational evidence, not RCTs, is the right test for a nutrient like vitamin D - review
• Clinically Isolated Syndrome (early MS) reduced 34% by bi-weekly 100,000 IU Vitamin D - RCT
• Vitamin D cut dental caries in half in 1930's – RCT meta-analysis
• Vitamin D given daily, weekly, or monthly has similar response (116 RCTs) – meta-analysis
• Little Vitamin D does not reduce risk of CVD – RCT meta-analysis
• 1.77 nmol response to 100 IU of Vitamin D (46 RCTs) – meta-analysis
• Vitamin D-disease associations vary with the type of study – RCT, Observational, MR
• RCTs probably not the future gold standard - CDC former head
• Vitamin D supplementation and fewer kidney stones – meta-analysis of RCT
• Vitamin D RDA of 600 IU is not enough - global RCT meta-analysis
• Sepsis: 4 fewer days in ICU if add Omega-3 – meta-analysis of 12 RCT
• Vitamin D supplementation improves muscle strength in healthy adults – meta-analysis of 6 RCT
• Variety of Vitamin D forms treat Prostate Cancer – RCT Review
• People supplemented with Vitamin D had 13 percent fewer Cancer deaths – Meta-analysis of RCT
• 2.7 fewer days in hospital after surgery if had taken Omega-3 (19 RCT) – meta-analysis
• Breast Cancer – review of 2 RCT did not find association with 1000 IU of Vitamin D
• Meta-analysis of RCT – vitamin D might increase senior muscle function
• Vitamin D and mortality a meta-analysis of RCT - 2008
• Creatine 10 g/day added about 1 kg of lean mass in 12 weeks in sedentary 45–65-year-olds, even without exercise - RCT
• Severe sepsis may be prevented by 400,000 IU of vitamin D – RCT 2023
• Bone gains from 2800 IU of vitamin D in pregnancy had faded by age 13 - RCT
• RCTs: The Foundational Flaw of Modern Medicine? - Cheng
• Vitamin D 1,600 or 3,200 IU for 5 years did not reduce fractures in Vitamin D–replete Finnish seniors - RCT
• 60,000 IU weekly vitamin D beat physiotherapy alone for chronic low back pain - RCT
• Resistance training 3X weekly in Type 2 Diabetes – 12 weeks - tiny RCT
• Pulmonary rehab aided by Vitamin D (60K weekly) - Asthma RCT Sept 2026
• The liposomal form of Vitamin D had the best response - RCT
• Many prenatal supplements contain only 1,000 IU of Vitamin D - proven by RCT to be of no benefit
• Tuberculosis not treated by monthly 140,000 IU (Vitamin D binding protein problem) – RCT
• 4,000 IU vitamin D did not change 25OHD to Vitamin D Binding Protein ratio for obese – RCT
• Tuberculosis, Genes, Vitamin D Binding Protein, and RCT – Review
• Response to Vitamin D varies with Vitamin D Binding Protein gene – RCT
• Poor protein binding gene associated with poor Vitamin D response – RCT
• Gave 1,000 IU of Vitamin D daily while pregnant (no surprise, no benefit) - RCT 2016
• 1,000 IU of Vitamin D while pregnant helped a little bit (4,000 IU helps a lot) – RCT 2016
• Weekly vitamin D in pregnancy/lactation did not improve infant growth – null RCT.
• Tobacco health problems reduced by Vitamin D (50,000 IU once every 2 weeks) - RCT
• 400,000 IU of vitamin D 3 days after COVID symptoms reduced 14 day mortality by 3X – Annweiler RCT
• Vitamin D average level was 33 ng after 400,000 IU in 2 months - RCT
• Endometriosis treated by Vitamin D (50,000 IU bi-weekly) – RCT
• BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT
• Lupus treated again by daily Vitamin D - 4,000 IU or 8,000 IU (slightly better) - RCT
• Migraine headaches cut in half by 4,000 IU of vitamin D – RCT
• 2000 IU of vitamin D for just 2 weeks helped in many ways – RCT
• Vertigo cut in half by weekly Vitamin D (10,000 IU) - RCT
• 24% lower risk of Autism for every 4 ng higher level of vitamin D during pregnancy - RCT
• Omega-3 reduced violence in children and violence between parents – RCT
• Infants getting an additional 800 IU of vitamin D for 2 years had 60% fewer psychiatric symptoms at age 7 – RCT
• If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT
• Calcitriol (fully activated Vitamin D) does not, on average, decrease in the winter if exercise - RCT
• Long-COVID in children (PASC) treated by daily 2,000 IU of Vitamin D - RCT preprint
• Water-dispersible Vitamin D may be gut-friendly (Cystic Fibrosis) – RCT
• 6,400 IU of Vitamin D is safe and effective during breastfeeding – RCT Dec, 2020
• Breastfeeding mother getting 6400 IU of Vitamin D is similar to infant getting 400 IU – RCT
• Raynaud's pain decreased with 600,000 IU monthly vitamin D – RCT
• Pain reduction with 600,000 IU Vitamin D: RCT announced
• Better outcome following Ischemic stroke if injected with 600,000 IU of vitamin D – RCT
• In vitro fertilization NOT helped by 600,000 IU of vitamin D – RCT
• Half as much AFIB after bypass if 600,000 IU of vitamin D before surgery – RCT
• COVID deaths cut in half by a single dose of 600,000 IU of Vitamin D - RCT
• Stress after natural disaster reduced by just 1000 IU Vitamin D – RCT
• Paxlovid does not fight COVID - 2 RCTS in NEJM
• Less scarring (hypertrophic) if supplementation with Vitamin D got above 25 ng – RCT
• Breast Cancer chemotherapy 3.6X better if Vitamin D was raised above 20 ng - RCT April 2025
• Upper canine teeth extracted faster if take Calcitriol (a form of Vitamin D) - RCT
• LDL Cholesterol reduced by Vitamin D plus Calcium – RCT
• Phizer RCT canceled April 2026- 80% of the healthy candidates had comorbidities (big increase due to Long-COVID)
• 400 IU of Vitamin D daily provided no benefit (UK RCT this time)
• Bronchiolitis hospital stay cut by 2 days with 200,000 IU vitamin D – if deficient – RCT
• Preterm birth rate cut in half with 1000 milligrams of Omega-3 (if initially low) – RCT
• Smokers helped by Vitamin D (100,000 IU monthly) - RCT
• Vitamin D helps sports - review of 45 RCTs
• Esophageal Cancer surgery helped by 300,000 IU of Vitamin D – RCT
• 3 lbs weight gain in just 3 weeks from Ultra-processed foods - RCT Oct 2025
• CFS following COVID infection or vaccination helped a bit by a little bit of Vitamin D - RCT Feb 2026
• Swine flu not prevented by 2,000 IU of vitamin D daily (the upper limit at the time) – RCT 2014
• Vitamin D: need 30 to 60 ng (50,000 IU weekly) RCT (Russia)
• Half as much Vitamin D needed if use nanoemulsion spray - RCT
• 4X reduction in prediabetes progressing to T2D if more than 50 ng of vitamin D – RCT
• 50,000 IU monthly safe to take without any vitamin D testing – RCT
• Alzheimer's proven to be prevented and treated - RCT 2026
• Risk of falling not changed by 1,600 and 3,200 IU Vitamin D - RCT
• RCTs should use individual vitamin D dosing to reach a preset level.
• BPPV (benign paroxysmal positional vertigo) decreased by Vitamin D - RCT Aug 2021
• Cardiovascular Disease risks reduced by weekly 50,000 IU Vitamin D - RCT Dec 2025
• 14 types of surgeries improved by Vitamin D - RCTs Dec 2025
• Heart attack risk halved in adults with heart disease if >40 ng level of vitamin D (RCT)
• 50,000 IU of vitamin D weekly for 8 weeks of pregnancy raised most above 30 nanograms - RCT
• 300,000 IU of Vitamin D total is not enough during pregnancy – RCT
• While in labor, preterm birth delayed 6 days by Vitamin D (single dose of 50,000 IU) - RCT
• Vitamin D and RCTs (Randomized Controlled Trials)
• Less weight gain if add Vitamin D, even if have a high fat diet (in rats) – RCT
• Nanoemulsion Vitamin D better (PCOS, perhaps poor gut) – RCT
• Atopic dermatitis reduced by at least half if take 2800 IU Vitamin D while pregnant - RCT
• Autistics have half of the response to Vitamin D – RCT
• Dental implants improved by nanoemulsion Vitamin D - RCT
• Vitamin D cut in half CIS resulting in MS lesions - RCT
• Leg cramp frequency reduced 2.7 X by 8 weeks of vitamin K - RCT
• Preemies getting a 10,000 IU injection of vitamin D had far fewer breathing problems – RCT 2024
• 1600 IU vitamin D safe for infants – RCT
• Supplement preterm infants with vitamin D if less than 80 ng – RCT
• Major Depressive Disorder RCTs often use Vitamin D: 50,000 IU weekly or single 300,000 IU - Review
• Breast Cancer survival improved 3.6X by 2,000 IU of Vitamin D with chemotherapy – RCT
• Sunburning reduced by 200,000 IU of Vitamin D – RCT
• Birth rates doubled with Vitamin D - 300,000 IU for infertile men – RCT
• Problem pregnancies (perinatal morbidities) 3.8 X less likely in blacks taking 4,400 IU of Vitamin D - RCT
• TB treatment helped by the addition of Vitamin D (100,000 IU bi-weekly) – RCT
• Magnesium raised Vitamin D, lowered blood pressure and Ca to Mg ratio – RCT
• Spinal fusion surgery greatly improved by Vitamin K2 - RCT
• PCOS menstrual periods regularized by Vitamin D - RCT
• Sexual dysfunction treated by 300,000 IU of Vitamin D – RCT
• Breast Cancer cure rate by chemotherapy increased 2.3 X by Vitamin D (50,000 IU weekly) - RCT
• ICU patients 6X more likely to die if poor response to 570,000 IU of Vitamin D – RCT
• CIS (MS) reduced 36% by two capsules of 50,000 IU of Vitamin D taken biweekly – RCT
• Centrum Silver increased facture risk (too little of Vitamin D and Calcium) - RCT
• 4.4 X INCREASE in other respiratory infections in children with influenza vaccinations – RCT
• Obese diabetics with dark skins not benefit from 6,000 IU of vitamin D daily (no surprise) – RCT
• Fish oil increased Vitamin D levels, krill oil decreased them – RCT
• Asthma reduced by 4,400 IU of Vitamin D while pregnant - RCT and video Weiss
• Topical vitamin D raised blood level to 38 ng (used Aloe Vera gel) – RCT
• Asthma reduced by weekly 50,000 IU of vitamin D – RCT
• Rickets prevented by single injection of vitamin D or weekly supplementation – RCT
• Surgery complications cut in half by 300,000 IU of vitamin D 2 weeks before (hip and knee) – RCT
• Single 600,000 IU dose of nanoemulsion Vitamin D is safe and effective to fight COVID, even if delay until enter ICU – RCT
• COVID and 25 Vitamin D RCTs discussed
• Vitamin D loading doses typically helped critically ill, but never harmed (21 RCTs)
• Over 48 Virus studies have RCT in the title
• Smoking depression, etc. reduced by Vitamin D (bi-weekly, 50,000 IU) - RCT
• Long-COVID reduced some by a small amount of Vitamin D and Vitamin K2 - RCT
• Earthing proven by RCTs to work - improves sleep, reduces blood viscosity, etc.
• MRSA Carriers not helped by 4,000 IU of Vitamin D (probably poor Vitamin D Receptor) – RCT
• Vitamin D and Calcium do not increase bone density (also need exercise, Mg, K2, protein etc.) – RCT
• VitaminDWiki items have phrase in the title: 986 Vitamin D, 357 Magnesium, 398 Omega-3, 985 RCT
• Weight loss includes muscle loss unless add vitamin D, whey and leucine – RCT
• Resulting childhood Asthma cut in half if 4,400 IU Vitamin D daily while pregnant - RCT
• 430 genes changed when 3,800 IU Vitamin D added in late second trimester – RCT
• TBI reduced 5X by 300,000 IU of vitamin D (injection) – RCT
• Dysmenorrhea substantially reduced by Ginger, just 1,000 IU Vitamin D also helped – RCT
• 44 percent of successful RCTs in VitaminDWiki used non-daily dosing
• Sleep disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT
• Following sleeve gastrectomy surgery, 3,000 IU of vitamin D daily for a year helped – RCT
• Migraine Headache duration and intensity reduced by 50,000 IU vitamin D every two week plus probiotics – RCT
• Non-RCTs may over-estimate benefits by 19%. by confounding, etc.
• Prisoners given Omega-3 for 3 months before release were 16% less likely to return in 3 years – RCT
• Higher bone density years later if mother had gotten just 1,000 IU vitamin D daily while pregnant – RCT
• Give ICU children a bolus dose of 10,000 IU of vitamin D per kg – RCT underway
• Dietary fat increased Vitamin D response by 32% – RCT
• Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT
• Chronic Heart Failure reduced by 4,000 IU daily for a year – RCT
• COVID 3X less likely if Xyilotol nasal spray 3X per day – RCT
• Children had a better response to Vitamin D given every 2 weeks than daily – RCT
• Viral infections reduced 40% by monthly 100,000 IU Vitamin D – RCT review
• Treatment of HIV in youths helped by 7,000 IU of vitamin D for 1 year – RCT
• 7000 IU vitamin D was not enough to reduce obese tissue – RCT
• Less ultramarathon heart damage if take 150,000 IU of Vitamin D a day earlier – RCT
• APOE-04 Alzheimer’s progression slowed up by Omega-3 – RCT
• Cows gave more milk after pregnancy if given Calcidiol (semi-activated Vitamin D) – RCT
• Long-COVID fatigue, anxiety, and cognition treated by 60,000 IU of vitamin D weekly – RCT
• 15.3 X fewer COVID deaths in those getting Vitamin D injections in ICU – RCT
• Should not add rock Calcium to Vitamin D (after 20 year followup: 6% increase in heart problems – no surprise) – RCT
• Omega supplementation helped preemie sensory processing – RCT
• 5,000 IU of Vitamin D daily resulted in far fewer hospitalizations - RCT
• 50,000 IU Vitamin D once every 2 weeks – response was 34 ng – RCT
• Bedwetting reduced 40 percent by 1,000 IU of vitamin D for 2 months – RCT
• Risk of going from pre-MS to MS reduced 68 percent with 7100 IU vitamin D – RCT
• 800 mg of Magnesium early in 3rd trimester significantly increased brain activity in preterm infants – RCT
• 4,000 IU of daily Vitamin D during pregnancy is good (Mongolia this time) – RCT
• 2X less risk of respiratory distress syndrome if 50,000 IU of Vitamin D just before premature birth – RCT
• Children with ADHD again helped by 50,000 IU weekly Vitamin D – RCT
• Chinese women in tropics needed 50,000 IU of Vitamin D monthly to keep above 30 ng – RCT
• Sepsis (with mechanical ventilation) treated by 5days of 50,000 IU of Vitamin D – RCT
• Military gave Vitamin D but only 40% got above 30 ng, no benefit was noticed for the entire group – RCT
• Bone fractures not reduced with 400 IU of Vitamin D plus Calcium (no surprise) WHI – strange RCT
• Following Digestive Cancer 2,000 IU of Vitamin D were given. Those whose Omega-3 levels rose had fewer Cancer problems – RCT
• Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006
• Less cognitive decline in older blacks getting 2,000 IU of vitamin D daily for years (VITAL, etc. post analysis) – RCT
• Sucrosomia Vitamin D appears to be 2 X more bio-available– RCT
• 50,000 IU of Vitamin D weekly greatly decreased bone loss from prostate cancer therapy - RCT
• Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT
• Ischaemic stroke – Vitamin D doubled survival (Injection followed by monthly 60,000 IU) – RCT
• Response to infant 2,000 IU Vitamin D daily was in 194 ng, monthly dosing was 20% less – RCT
• Immune systems of overweight black women improved by monthly 60,000 IU Vitamin D – RCT
• 100,000 IU of Vitamin D3 monthly for 4 months to diabetics (D2 bombed) – RCT
• Monthly 120,000 IU of Vitamin D while breastfeeding was good – RCT
• Asthma and COPD in a few seniors greatly decreased by monthly 100,000 IU Vitamin D – RCT
• Bone density improved by monthly 50,000 IU of vitamin D for 6 months – RCT
• 100% not need COVID hospitalization with fluvoxamine plus one other drug – Thailand RCT
• Atopic Dermatitis not helped by small weekly doses of Vitamin D (8K 2y-6y.16K 12y-18y) – RCT
• Individualized – RCT
• Muscles improved in women with 50,000 IU vitamin D weekly (8 weeks) plus daily Magnesium – RCT
• Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT
• Vertigo incidence reduced 40% by just 7,000 IU Vitamin D given weekly - RCT
• 2800 IU of Vitamin D in late pregnancy resulted in 3X fewer fractures, 4X fewer enamel defects in offspring – RCT
• Half of infants had less than 20 ng of Vitamin D with 800 IU (need more) – RCT
• 4,000 IU of Vitamin D daily is safe, but takes a year to plateau (Best-D) – RCT
• Preeclampsia risk reduced 7X by 4,000 IU of Vitamin D daily – RCT
• Risk of Frailty reduced 4X by 4,000 IU of vitamin D – RCT
• Respiratory infections reduced by 63 percent with 4000 IU vitamin D daily - RCT
• Obese asthmatic children Vitamin D - 50,000 IU then 8,000 IU daily - RCT
• Smoking desire decreased after Omega-3– RCT
• PMS reduced by 50,000 IU every two weeks - RCT
• COVID fought by Vitamin D: OBSERVATIONS: YES, RCTs: NO
• Gestational Diabetes best fought by Vitamin D plus probiotics – RCT review
• COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT
• Estradiol, vitamin D, Omega-3 – RCT
• Vitamin D response: 800 IU: 20 ng, 3200 IU: 45 ng – RCT
• COVID-19 outpatients getting Quercetin nanoemulsion had excellent outcomes (Q increased Vitamin D in cells) – RCT
• Bone Mineral Density increased by Resveratrol (which activates the Vitamin D Receptor) – RCT
• TB again not prevented by a small amount of Vitamin D – RCT
• Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT
• Vitamin D loading dose of 30,000 IU twice a week is safe and effective – RCT
• Depression greatly reduced by taking 250 mg of Magnesium Chloride daily for 6 weeks– RCT
• Bone fractures of children not reduced if given little vitamin D, no Calcium etc. – RCT
• Dieters lost 5 more pounds if achieved more than 32 ng of vitamin D – RCT
• Autistic symptoms reduced by Vitamin D and or Omega-3 – RCT
• Cancers reduced after 2 years of 2000 IU Vitamin D daily (2nd RCT) – RCT Aug
• Vitamin D 100,000 IU loading dose and stem cell transplants – RCT
• 4,000 IU Vitamin D daily during pregnancy (Mongolia) was good – RCT
• 5000 IU Vitamin D daily resulted in lower health care costs - RCT
• 2.5 X reduced risk of cancer in 70 year-olds by a small amount of Vitamin D, Omega-3 and exercise – RCT
• Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT
• Infant infection reduced by half with vitamin D supplementation – RCT
• Respiratory Tract Infection visits 2.5 less likely with vitamin D: Pregnancy 2000 IU, Infant 800 IU – RCT
• Parkinson’s disease: Review of low-dose vitamin D RCTs found small benefit
• Influenza infection 5X less likely if got vitamin D – small RCT
• COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT
• Gingivitis (inflammation of the gums) substantially reduced by Vitamin D – RCT
• Venous ulcers healed 4X faster with weekly 50,000 IU vitamin D – RCT
• ICU Vitamin D injection (300,000 IU) helped - RCT
• Chronic Periodontitis reduced by Vitamin D (60,000 IU weekly for 8 weeks) – RCT
• Vitamin D3 fortified bread better than 1,000 IU supplement – RCT
• 3X less Septic Shock in children with sepsis getting 150,000 IU of Vitamin D - RCT
• Muscle pain in obese women reduced by aerobic exercise plus 50,000 IU Vitamin D - RCT
• Breast Cancer survival: 44% with just 10,000 IU of vitamin D per week, 33% with placebo – RCT
• Senior Cognition not improved by 2,000 IU Vitamin D avg.- RCT
• NAFLD in children nicely treated by combination of Vitamin D and Omega-3 – RCT
• Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT
• Investigation of segregated patient groups may be more effective than classical vitamin D RCTs - Carlberg
• Diabetic foot ulcers healed 2X faster with 6,400 IU daily - RCT
• Schizophrenia severity reduced somewhat by daily 2,000 IU of Vitamin D – RCT
• Sleep greatly improved by 50,000 IU of vitamin D once every two weeks – RCT
• Smoking does not decrease response to monthly Vitamin D – RCT
• 1 % weight loss delays brain aging by nearly nine months - RCT
• Burns - will 200,000 IU of vitamin D decrease hospital stay - RCT 2021
• Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs
• Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT
• Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT
• Prenatal Omega-3 somewhat reduced child allergies (should also reduce Omega-6) – RCT
• Omega-3 did not prevent depression (they failed to reduce Omega-6, which blocks Omega-3) – RCT
• Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT
• 10,000 IU of Vitamin D is too much if you also take Calcium supplements – RCT
• Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT
• 50,000 IU of Vitamin D every 2 weeks reduced gestational diabetes – RCT
• Afib in Finland reduced 30% by Vitamin D (3200 IU) – RCT
• COVID in hospital stopped by Vitamin D Receptor activators (curcumin, quercetin) – RCT
• Fracture 4X less likely following kidney transplant if high-dose Vitamin D (100,000 every 2 weeks) – RCT
• Fewer children died of pneumonia after 100,000 IU Vitamin D injection – RCT
• Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT
• Little second-hand smoke problem in children if mother had added Vitamin D while pregnant - RCT
• Tuberculosis not treated by lots of vitamin D for 16 weeks – RCT
• Tuberculosis not prevented by a tiny amount of vitamin D (equiv to 1,400 IU daily) – RCT
• TB not treated by vitamin D given for only 2 months – RCT
• Benefits of Omega-3 plus Vitamin D were additive – RCT
• Omega-3 supplementation reduced preterm birth rate by 4X – RCT
• Attention Deficit Hyperactivity Disorder impulsivity reduced by daily 1,000 IU of vitamin D – RCT
• ADHD significantly treated by daily Magnesium plus weekly Vitamin D – RCT
• Autism problems reduced by Vitamin D, Omega-3 – RCT
• 200 IU of Vitamin D does not prevent preeclampsia – RCT
• Multiple Sclerosis is again not fought by 5,000 IU vitamin D daily (need at least 10X more) – RCT
• Exercise improves bone strength (good), but not bone mineral density (can be measured) – RCT
• Vitamin D treatment of Chronic Kidney Disease: monthly better than daily – RCT
• Following breast cancer 100K IU Vitamin D doses twice a month helped a lot – RCT
• More Calcium absorbed with more vitamin D – 6.7% more with 4000 IU – RCT
• Psoriasis reduced for those getting Vitamin D levels above 50 ng – RCT
• Bone mineral density improvement by Vitamin D plus fluoride is augmented by laser acupuncture – RCT
• Urinary Incontinence reduced by 50,000 IU of vitamin D weekly (details behind paywall) – RCT
• Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT
• COVID recovery 1.6X faster after 200,000 IU of Vitamin D RCT
• Weekly 50,000 IU of vitamin D is again found to be good – RCT
• Crohn’s Disease reduced for a year by 7 weeks of high dose Vitamin D – RCT
• 1289 genes changed with higher doses of Vitamin D - RCT
• Lupus: 60,000 IU Vitamin D monthly got to only 34 ng, not enough to help – RCT
• After Colorectal Cancer Surgery the immune system was maintained by Vitamin D (8,000 IU daily) – RCT
• Uterine Fibroids cut in half in group taking 1,000 IU of Vitamin D - RCT
• 1 in 3 died after hip fracture but only 1 in 14 if add Vitamin D and exercise – RCT
• Hip fracture recovery best with home exercise plus Vitamin D – RCT
• Early COVID treatments rarely work 7 days after symptoms, this trial gave Vitamin D on 7th day – RCT
• Hyperparathyroidism resulting from CKD eliminated by 8,000 IU of vitamin D daily for 12 weeks– RCT 2018
• Vitamin D once during pregnancy reduced infant health care costs (300 times ROI) – RCT
• COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT
• Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc.
• Long-COVID fatigue reduced by Vitamin C and l-Arginine in one month– RCT
• Dark-skinned infants got minimal vitamin D from 4 minutes sunbathing daily – RCT
• Taking Vitamin D just before and after surgery helps (open-heart in this case) – RCT
• Depression decreased by Vitamin D (12th study in VitaminDWiki) – RCT
• Grip strength of children not improved by 800 IU Vitamin D daily (not nearly enough) – RCT
• Colorectal Cancer – vitamin D did not help (too small of a response) – RCT
• Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT
• Ultra-low UV LED added to office desk lamp would add 7 ng to winter Vitamin D levels – RCT
• Vitamin D2 again decreased vitamin D3 levels – RCT
• COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT
• COVID-19 defeated by calcifediol form of Vitamin D in Spain - pilot RCT
• COVID-19 ICU survival rate increased 7X by daily Omega-3 – RCT
• Vitamin D not help 10 days after COVID-19 symptoms - RCT
• COVID-19 appears reduced by Resveratrol plus 100K IU of vitamin D – Small RCT
• Nursing home vaccinated against Influenza, 800 IU of vitamin D daily cut infection rate in half – small RCT
• Tested positive for COVID, taking probiotics stopped symptoms 5 days sooner - RCT
• COVID in hospital fought by Vitamin D (25,000 IU daily for 4 days, then 25K weekly) - RCT
• Vitamin D does not help when most are not deficient (cataract surgery in this case) – RCT
• Candida infections in PICU reduced by Vitamin D in yogurt – RCT
• 3,200 IU of daily not help much in population already having 30 ng of Vitamin D – RCT
• Small Vitamin D doses for a short time never help (not improve vaccination in this case) – RCT
• The challenges of a Vitamin D RCT – too many already taking it, etc. – Martineau
• One day of 12,000 IU of sublingual Vitamin D raised levels by 8.6 ng in 5 days – RCT
• Cod liver oil does not prevent Respiratory Infections (no surprise, only 400 IU of vitamin D) RCT
• Risk of COVID not reduced by 3,200 IU of vitamin D during 6 months (no surprise) – RCT
• Atrial Fibrillation risk reduced by 0.84 in those raising Vitamin D levels above 30 ng – RCT
• Overweight needed more EPA (4 grams) to fight depression – RCT
• 1 pill a day is better than multiple (probably 1 per 2 weeks would be even better) - RCT
• Prebiotics increased Vitamin D in celiac disease patients (gut-friendly Vit. D also helps) – RCT
• Faster growth in infants getting 1200 IU of Vitamin D – RCT
• Breastfed Infants need more than an daily average of 800 IU of Vitamin D – RCT
• Children need 2000 IU of Vitamin D (India) - RCT
• Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT
• 60,000 IU of vitamin D monthly is healthy and safe – RCT
• More Magnesium needed by obese (Mg Sulfate, women in this case) – RCT
• Diabetic hypertension reduced with Vitamin D and Calcium – RCT
• 200 IU of vitamin D while pregnant raised levels by a paltry 2 ng – RCT
• Weight loss with salacia reticulata and just 200 IU of vitamin D – RCT 2013
• Unethical to restrict Vitamin D to half of the asthmatic children in RCT
• No Preeclampsia during pregnancy if more than 60 ng of vitamin D – RCT
• Gestational diabetes treated by Vitamin D plus Omega-3 – RCT
• Asthma attacks reduced in half if Vitamin D level higher than 42 nanograms – RCT
• Hypertension (both systolic and diastolic) reduced with 2,000 IU of vitamin D – RCT
• 50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT
• Severe acute pancreatitis treated in 11 ways by Omega-3 in just 7 days – RCT
• Hypertension reduced by Magnesium plus 3,000 IU of vitamin D for 12 weeks – RCT
• Magnesium and Vitamin D - pre-colon cancer – RCT
• 4X less likely to get COVID following 4,000 IU daily for a month – RCT
• Multiple Sclerosis relapses cut in half by 100,000 IU of Vitamin D every 2 weeks– RCT 2019
• Vitamin D for infants – 100,000 IU monthly is better than 400 IU daily – RCT
• Nutritional RCTs: types and concerns
• Increasing the ratio of mono to poly fats increased Vitamin D levels by 6 ng – RCT
• Urate (kidney stones, gout) reduced by Calcium – RCT
• Loading dose of Vitamin D for patients hospitalized with COVID (140,000 IU) – RCT completed 2021
• Short-term response to 1,000 IU of Vitamin D tripled in obese when Magnesium was added – RCT
• HIV not helped by 2,000 IU of Vitamin D (no surprise) – RCT
• 21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
• Pregnant women in HIV therapy adding Vitamin D had 3X fewer deaths - RCT
• Breast Cancer not prevented by 1,000 IU of Vitamin D (no surprise) – RCT
• 4,000 IU of Vitamin D is too small a dose to help Obese - RCT
• 10,000 IU of Vitamin D for 3 years found to help bone by two measurement methods – RCT
• Influenza vaccine antibodies not change with Vitamin D – 21 ng or 44 ng – RCT
• Response to Vitamin D varies with genes (3,000 IU, weight loss in this RCT)
• Handgrip strength increased 9 percent in college athletes with 8 weeks of Omega-3 – RCT
• Stroke patients need more than 2,000 IU of vitamin D (found this time in Japan) – RCT
• Monthly vitamin D helped hearts with low vitamin D a bit (need it more frequently) – RCT
• Sleep not helped when half got to 35 ng of Vitamin D (may need 60 ng) – RCT
• Teeth alignment completed faster if good levels of vitamin D – RCT
• Tuberculosis treatment helped a bit by a bit of Vitamin D - RCT
• HIIT reduced appetite of sedentary overweight men, adding a bit of vitamin D helped a bit – RCT
• Preterm birth rate of pregnant smokers cut in half if take Omega-3 – RCT
• Group achieving 30 ng (vs 26 ng) were 2X less likely to get COVID symptoms - RCT
• More dental implant bone growth if high vitamin D (natural or supplement) – RCT
• Nutritional supplementation during COVID hospitalization helped - RCT
• NAFLD not reduced by 1680 IU of vitamin D plus Omega-3 (no surprise) – RCT
• Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT
• Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT
• Resistance training can be aided by Vitamin D, 50,000 IU monthly is not often enough – RCT
• 50,000 IU of vitamin D monthly in winter gets most above 20 ng – RCT
• Vitamin D reduced bacterial infection in cows – RCT
• Mortality reduction needs more than monthly 60,000 IU of Vitamin D - RCT
• IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT
• Off Topic: EDTA similar reduction in heart attack as Vitamin C, aspirin and Mg – RCT
• Blotchy skin in seniors (Bateman purpura or dermatoporosis) treated by topical vitamin C, etc. – RCT
• Most Diabetics getting 40,000 IU of vitamin D weekly did not get to 30 ng (needed gut-friendly form) - RCT
• 2,000 IU of vitamin D and Omega-3 reduced Cancer death rate bv 40% (normal weight) – VITAL RCT
• Low vitamin D while pregnant increases risk of autism (a 2016 RCT reduced risk by adding Vitamin D)
• Stoss (loading) dose of vitamin D resulted in bigger response at 30 days (again) – RCT
• Many healthy African Americans got above 33 ng with 4,000 IU of vitamin D – RCT
• Additional Vitamin D not help – infants previously had 35 ng of vitamin D – RCT
• Added 1 lb of muscle to sarcopenia adults in 13 weeks with just 800 IU vitamin D and protein – RCT
• A small amount of Vitamin D for a short time does not help (2800 IU, 8 weeks) – RCT
• Severe Non-Alcoholic fatty liver disease treated by Omega-3 – RCT
• Non-Alcoholic Fatty Liver Disease (NAFLD) treated by Vitamin D (20,000 IU weekly after loading dose) – RCT
• Fewer days in hospital if 300,000 IU of vitamin D before brain surgery - RCT
• 18 fewer hospital days if given 500,000 IU of vitamin D while ventilated in ICU – RCT
• TB not prevented by a small amount of Vitamin D (2,000 IU daily average, Mongolia) – RCT
• RTI – Feel much better if increase vitamin D level above 40 ng (4000 IU) – RCT
• Respiratory infections (RTI) cut in half by 20,000 IU weekly vitamin D if initially deficient – RCT
• Menstrual Pain (PMS) reduced by vitamin D – RCT 2012, 2014, 2016
• PMS again significantly reduced by 50,000 IU of vitamin D (This time, every two weeks) – RCT
• Tuberculosis recovery speeded up by single 450,000 IU dose of vitamin D – RCT
• ADHD 1.5X less likely if 4,400 IU Vitamin D daily during pregnancy - RCT
• Omega-3 paused Alzheimer's decline - RCT
• Infants getting 800 IU more vitamin D daily got no neuro benefit (virtually all Fins were sufficient) – RCT
• Calcifediol (Calcidiol) is far less cost-effective and available than Vitamin D – RCT
• 400 IU of Vitamin D helped breastfed infants, need more – RCT
• NAFLD somewhat treated in children with 2,000 IU Vitamin D daily – RCT
• Mother got 100,000 IU of vitamin D monthly, breastfeeding infant got a little – RCT
• Daily, monthly Vitamin D had similar great benefits, more than 6 months needed – RCT
• Vitamin D given for 6 weeks did not slow prediabetes progression 2 years later (no surprise) – RCT
• Hemodialysis not helped by weekly vitamin D2 – RCT
• Vitamin D2 decreases levels of D3 (again) and visa versa – RCT
• Breastfed infant bones not helped by 800 IU of Vitamin D (not enough) – RCT
• Antibiotic use cut in half by elderly (over 70) after monthly 60,000 IU of vitamin D – RCT
• Vitamin D supplementation protocols: loading, injection, etc – RCT
• 40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008
• Sublingual vitamin D gave similar response as oral for most, and better for some – RCT
• Rectal Cancer genes down-regulated by Vitamin D (3,200 IU only helped some) – RCT
• Falls not decreased by 60,000 IU Vitamin D monthly (not a news item) – RCT
• Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
• IBS not helped by daily 3,000 IU Vitamin D (but non-daily and gut-friendly help) – RCT
• Irritable Bowel Syndrome - can it be treated by 3000 IU of vitamin D - RCT
• Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT
• 5,000 U daily raised Vitamin D a bit and helped COVID-19 a bit – RCT
• Hay Fever treated by Vitamin D (50,000 IU weekly) – RCT
• Athletes helped by weekly 50,000 IU Vitamin D – RCT
• Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT
• Response to weekly Calcifediol in 4 months - RCT
• Infant Respiratory Infections not reduced by mothers taking small amount of vitamin D (28,000 weekly)– RCT
• Melanoma not treated by small doses of vitamin D (100,000 IU every 50 days) – RCT
• Digestive Tract Cancer survival increased 3X if 2,000 IU of vitamin D and have high level of PD-L1 – RCT
• 400 IU of Vitamin D provided no benefit to children (not a surprise) – RCT
• Fewer pre-infants were vitamin D deficient when they got 800 IU – RCT
• Monthly 100,000 IU of vitamin D is safe (and may be better than daily) – RCT
• Single 200,000 IU of vitamin D did not benefit the obese in various ways (not a surprise) – RCT
• Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT
• Psoriasis proven to be treated by Vitamin D in many RCT, but dermatologists fear losing business
• Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023
• Vitamin D supplementation resulted in thicker Brain Cortex – RCT
• Dementia risk reduced 29 percent by just 10 hours of computer brain plasticity training – RCT
• Every TB patient benefited from 2 doses of 600,000 IU of vitamin D – RCT
• Calcifediol is superior to cholecalciferol (it mainly acts faster) – RCT
• Inflammation reduced by a single dose of Vitamin D (200,000 IU) – RCT
• Ulcerative Colitis significantly reduced by 480,000 IU loading dose of nano Vitamin D – RCT
• Need 3X more Vitamin D (or take semi-activated vitamin D) if have poor gut – small RCT
• 5X less likely to enter ICU with COVID-19 if get Calcifediol (semi-activated vitamin D) - RCT
• Vitamin D reduced COVID-19 inflammation (60,000 IU daily for 8 days) - RCT
• 291 genes improved expression by 2000 IU of vitamin D – RCT
• Overweight elderly respond well to 3600 IU Vitamin D daily for a year – RCT
• Bone healing not improved by a single bolus dose of 30,000 IU (no surprise) – RCT
• 50,000 IU of Vitamin D once every 2 weeks achieved 40 ng in 3 months – RCT
• Weekly response to semi-activated vitamin D slightly better than standard – RCT
• Vitamin D every 25 days may be BETTER than daily – RCT
• Prediabetes reduced in half by those getting Magnesium Chloride – RCT
• Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT
• Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT
• Recurrence of child pneumonia delayed by 100000 IU of vitamin D – RCT
• Crohn’s disease helped when vitamin D level raised above 30 ng – RCT
• Diverticular disease:12X reduction if low Vitamin D and given 100,000 IU monthly – RCT
• Half the risk of Influenza -A in infants taking 1200 IU of vitamin D for 4 months – RCT
• Omega-3 prevents Parkinson’s Disease – Review of RCT
• Wisdom tooth (3rd molar) extraction helped by Vitamin D loading dose – RCT
• Giving vitamin D stopped bone loss, stopping vitamin D let the bone loss continue – RCT
• Cardiovascular Disease prevented by Vitamin K2-4 when enough is used – RCT review
• Zinc supplementation increased Vitamin D levels – RCT
• Severe COVID-19 not fought by vitamin D when given too late - RCT
• Crohn's Disease relapse rate of 3 in 8 with 1,000 IU vs 0 in 12 with 10,000 IU of Vitamin D – RCT
• Anti-inflamatory cytokines increased when vitamin D levels were raised above 30 ng – RCT
• RDA of Vitamins and minerals reduced incarceration by 2,993 dollars per prisoner – RCT
• Far more Vitamin D in breast milk from a 150,000 IU dose than from daily 5,000 IU – RCT
• Vitamin D is aided by probiotics (review of RCTs)
• Takes a year to restore children and youths to good levels of vitamin D without loading dose - RCT
• Upper Respiratory Tract Infections in adults reduced by just 400 IU of vitamin D – RCT
• Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT
• Mild cognitive decline reversed by a year of just 800 IU Vitamin D daily – RCT
• Cognitive decline not helped by daily vitamin D getting to just 30 ng – RCT
• 9,000 dollar prize for RCT which found cognition improved after taking 4,000 IU of Vitamin D for 18 weeks
• Obese teens need more than 2,000 IU of vitamin D for 3 months– RCT
• Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT
• Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT
• Toddlers with more than 48 ng of vitamin D weighted less and were thinner – RCT
• 500,000 IU of vitamin D cut in half the hospital days following a lung failure – RCT 2015
• Vitamin D (10,000 IU) changes bacteria in the gut – RCT
• During pregnancy even 400 IU helps metabolic status – RCT
• Early Rheumatoid Arthritis helped by 300,000 IU of vitamin D – RCT
• Vitamin D reduced depression – single 300,000 IU – RCT
• Global Push for RCTs in COVID-19
• 2000 IU vitamin D not enough to get most Chinese to 20 ng level – RCT
• Elderly Vitamin D Loading Dose of 500,000 IU is safe and effective – RCT 2009
• 4,000 IU of vitamin D for 1 month does not help (muscles in this case) – RCT
• Influenza reduced by 1.7 with 1200 IU D3, also reduced related asthma by 6X – RCT
• Vitamin D injection is far better than oral for diabetics (poor gut) – RCT
• HIV patients helped by monthly 120,000 IU of Vitamin D – RCT
• College swimmers helped by daily 5,000 IU of Vitamin D in the fall – RCT
• Acute respiratory infection worsened by too infrequent vitamin D supplementation – RCT
• Children in Mongolia helped by 800 IU of Vitamin D (need a lot more) – RCT
• Vitamin D needed to get children to just 20 ng in winter 800 IU white skin, 1100 IU dark (Sweden) – RCT
• UVA decreased serum levels of vitamin D - RCT
• Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT
• Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT
• Weekly oral Vitamin D recommended before surgery (Bariatric in this case) – RCT
• 300,000 IU injection loading dose of vitamin D3 stopped gestational diabetes in RCT
• ICU adults getting 540,000 IU of Vitamin D were 2X more likely to be alive 30 days later – RCT
• 5 days of 100,000 IU of Vitamin D increased hemoglobin in critical illness – RCT
• Newborn Vitamin D - single 50,000 IU is better than daily – RCT
• Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT
• 24 ng lower response to Vitamin D due to obesity, low initial Vitamin D, and genetics – RCT
• 100,000 IU daily of Vitamin D for 5 days increased Hemoglobin in Mechanically Ventilated adults – RCT
• Childhood colds reduced 25 percent by weekly Vitamin D – RCT
• 2X improved development by severely malnourished children with 2 loading doses of vitamin D – RCT
• Child soccer players who were deficient were helped by a single 200,000 IU vitamin D dose – RCT
• 10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT
• Soccer improved in children by a single 200,000 IU dose of Vitamin D – RCT
• Vitamin D improves T Cell immunity – RCT
• Obesity not helped by daily vitamin D (summary of 20 RCTs using 100 IU to 8,000 IU)
• Monthly 100,000 IU of Vitamin D adds about 25 ng - RCT
• Response to 150,000 IU vitamin D once vs 5,000 IU daily – RCT
• Diabetic inflammation reduced by Vitamin D (30,000 IU weekly) – RCT
• Diabetes (Type II) reduced by single injection of 300,000 IU of vitamin D3 – RCT
• Ulcerative colitis treated by injection of 300,000 IU of vitamin D – RCT
• Vitamin D levels in children optimized with six Vitamin D biscuits – RCT
• Rheumatoid Arthritis not helped by a single small dose of vitamin D (not a surprise) – RCT
• Lupus flareups cut in half by just 2,000 IU of vitamin D – RCT
• Little weight loss in obese children from very small amount of vitamin D (1200 IU) – RCT
• Found again – 400 IU of Vitamin D rarely provides any benefit (infant allergy in this case) – RCT
• Monthly vitamin D dosing had higher response than 3 per month – RCT
• Tuberculosis is not treated by 400 IU of vitamin D – RCT
• COPD trial to use 80,000 IU of vitamin D weekly – RCT 2021
• Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT
• Respiratory Virus risk reduced 35 percent by Vitamin D (14,000 IU weekly) – RCT
• Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT
• Diabetes not helped by increasing Vitamin D levels to 20 ng (proven again) – RCT
• Rapidly restore Vitamin D levels with 10,000 IU per kg for children in ICU – RCT 2024
• Probiotics increased Vitamin D etc in healthy children – RCT
• Vitamin D intervention for 8 weeks of pregnancy: infants taller, heavier and bigger heads – RCT
• 2 X better survival of digestive cancer if 2,000 IU of Vitamin D plus good VDBP gene – RCT
• Dengue virus prevented by a small amount of Vitamin D – RCT
• Respiratory tract infection eliminated in 36 percent of people by 4000 IU of Vitamin D – RCT
• Senior muscles increased somewhat with Omega-3 – RCT
• Following brain surgery Vitamin D injections did not raise blood levels much – RCT
• Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT
• 20,000 IU of Vitamin D weekly gave many benefits – RCT
• Vaccine antibody generation not change with Vitamin D – 21 ng or 44ng – RCT
• Lower back pain treated by 600,000 IU of Vitamin D – RCT
• Diabetes helped by 5,000 IU of Vitamin D – RCT
• Less response to 800 IU of Vitamin D by Africans than natives in Finland – RCT
• Obese responded to weekly vitamin D better than non-obese – RCT
• Obese taking 50,000 IU of vitamin D weekly lost more weight (again) – RCT
• 2X less muscle soreness after exercise if Omega-3 index higher than 4 – RCT 2014
• Hens with Vitamin D were better in at least 5 ways – RCT
• Vitamin D fortification of milk helps (proven in Gemany this time) – RCT
• Spinal disc degeneration reduced by Omega-3 (in rats) – RCT
• Sepsis mortality cut in half with Omega-3 – RCT
• Omega-3 reduced cost of Sepsis by 2900 dollars per patient (12 RCT)
• Vitamin D changed microbiota in gut and airway, might reduce cystic fibrosis – RCT
• Prostate Cancer treatment (Vitamin D, Omega-3, Tumeric) RCT ending
• Turmeric stopped Ulcerative Colitis – RCT
• Happy Nurses Project gave Omega-3 for 3 months – reduced depression, insomnia, anxiety, etc for a year – RCT
• Multiple Sclerosis treated by 50,000 IU Vitamin D bi-weekly plus Omega-3 – RCT
• Lymphoid cancer deaths cut in half with 400 IU of vitamin D and 1 gram of Calcium (WHI) – RCT
• Lean body mass increased in those getting just 420 IU of vitamin D daily– RCT
• Salmon dinners (400 IU Vitamin D daily) not enough to stop winter decline (Norway) – RCT
• Using natural experimental studies to guide public health action, not RCTs
• 10,000 IU of Vitamin D taken daily for 3 years is safe – RCT
• Influenza A: 5X reduction in first month (only) with 2,000 IU of vitamin D– RCT
• Muscle strength of Judo athletes increased 13 percent following single dose of 150,000 IU vitamin D – RCT
• Exercise plus vitamin D increases elderly muscles (Nordic walking in this case) – RCT
• Cystic fibrosis problems cut in half by Omega-3 – RCT
• Cystic Fibrosis not helped by 50,000 IU of Vitamin D taken twice a month – RCT
• Bones of white children not helped by 1,000 IU of vitamin D (Northern latitudes) – RCT
• Cystic Fibrosis exacerbation reduced by Vitamin D (250,000 IU) – RCT
• Diabetes increases risk of poor cognition by 2X, 12 weeks of Vitamin D not help (but 18 weeks did) – RCT
• Digestive track Cancer (poorly differentiated) death 4X less likely if 2,000 IU of vitamin D – RCT
• Vitamin D and Omega-3 may treat Type 1 Diabetes – RCT 2024
• Low vitamin D newborns getting cows milk formula more likely to get allergies – RCT
• 2000 IU of vitamin D reduced fatigue of advanced cancer – RCT
• Vitamin D – monthly dosing was better than daily with Calcium – RCT
• 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT
• 50,000 IU Vitamin D one time after birth helped – RCT
• Prediabetes corrected in 3 months by 1,000 IU of vitamin D as pill or in yogurt – RCT
• Hospital-acquired pneumonia treated by vitamin D if person was deficient – RCT
• COPD quality of life improved by 400,000 IU Vitamin D loading dose – RCT
• 1700 IU vitamin D (50000 monthly) helped antarctic explorers – RCT
• Extreme preterm infants helped somewhat by 800 IU of vitamin D – RCT
• Taekwondo athletes helped by just 1 month of Vitamin D (longer would be better) - RCT
• 1,000 IU of Vitamin D provided no benefit (Royal Ballet in this case) – RCT
• Biochemical rickets non-existent if breastfeeding mother got 600,000 IU of vitamin D (3 dollars) – RCT
• 5,000 IU Vitamin D daily resulted in many benefits after 3 months (US soldiers) – RCT
• Parkinson's disease stabilized with just 1200 IU of vitamin D – RCT
• Severely Obese not helped much by 50,000 IU of vitamin D weekly for 8 weeks – RCT
• Can burn pain be relieved by 4 g of Omega-3 and 2,000 IU of vitamin D – RCT due 2021
• Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT
• 3 weeks of Vitamin D can not help much (Breast Cancer surgery in this case) – RCT
• Atopic dermatitis dramatically reduced in Iran with 1600 IU of vitamin D – RCT
• Atopic dermatitis treated by Vitamin D (in dogs too) - RCT
• Diabetics and prediabetics helped by 5,000 IU of Vitamin D for 6 months– RCT
• Occupational burnout reduced after 8 weeks of Omega-3 – RCT
• Preemie immunity (Treg) vastly improved by 800 IU of Vitamin D daily – RCT
• Infants receiving 1600 IU of vitamin D were safe and healthy – RCT
• Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT
• Allergic Rhinitis (hay fever) reduced by just 1,000 IU of vitamin D for 30 days – RCT
• Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT
• Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT
• Less bone loss if take 100,000 IU vitamin D monthly – RCT
• Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT
• Diabetic inflammation reduced by Calcium and 50,000 IU of vitamin D in 8 weeks – RCT 2014
• Allergic rhinitis in children reduced somewhat during pollen season by just 1,000 IU of vitamin D – RCT
• Treatment of neonate sepsis greatly aided by Vitamin D – RCT
• Risk of infant Asthma cut in half if mother supplemented Vitamin D to get more than 30 ng – RCT
• Asthma in 3 year olds decreased somewhat with 4,000 IU during pregnancy – RCT
• Improving RCT design for testing Vitamin D health benefits
• Childhood Asthma risk greatly reduced if mothers were given 4,400 IU Vitamin D daily – RCT 2019
• Omega-3 reduced by 4X the interruption of Cervical Cancer chemotherapy due to toxicity – RCT
• 4X reduction in bone fractures following Kidney Transplant with monthly Vitamin D (100,000 IU) - RCT
• Methadone cognition improved by 50,000 IU of vitamin D every 2 weeks – RCT
• 300,000 IU Vitamin D injection before brain tumor surgery – RCT to finish
• VITdAL-ICU - AMA RCT
• Will lots of vitamin D help in ICU – RCT protocol
• Risk of Metabolic syndrome for senior women reduced 42 percent by 1,000 IU of vitamin D – RCT
• Autism in children reduced by Vitamin D (used 300 IU per kg per day) – RCT
• Spinal Cord injury outcome was better if got Vitamin D and progesterone within 4 hours – RCT 2016
• Football Brain injuries prevented by Omega-3 – RCT
• Loading dose greatly improves subsequent daily Vitamin D if have liver fibrosis – RCT
• Resveratrol prevented bone loss associated with T2DM (probably via VDR) – RCT
• Bone density improved with resveratrol (which improves Vitamin D Receptor) – RCT
• Decrease of Alzheimer’s biomarker halted by Resveratrol (perhaps due to vitamin D) – RCT
• Vitamin D does not treat colon cancer (when you only use 1,000 IU) – RCT
• Omega-3 helped Alzheimer’s only if good level of B vitamins – RCT
• Digestive tract cancer death rates reduced a bit by a bit of vitamin D – RCT
• Advanced Colorectal Cancer survival is increased somewhat with 4,000 IU of vitamin D – RCT
• Sunscreen (SPF-30) slightly increased the vitamin D from UVB – RCT
• 25 minutes of daily sun provided less than half of the response as 500 IU of vitamin D (Korea) – RCT
• Fluoride caused bone problems in 80 percent of Vitamin D deficient rats – RCT
• 4 weeks of Omega-3 better than 2 week 800 calorie diet before Bariatric Surgery – RCT
• Bacterial vaginosis reduced 10 times by 2,000 IU of vitamin D – RCT
• All preteen aged girls in India taking 2,000 IU of vitamin D got levels above 20 ng – RCT
• Monthly Vitamin D had a 20 percent better response than quarterly – small RCT
• Iron increased slightly by small amount of Vitamin D for a short time – RCT
• Younger Parkinson’s patients had better balance after 10,000 IU of vitamin D for 16 weeks – RCT
• Fetal bones helped a bit by 1,000 IU of vitamin D – RCT
• Adding 1,000 IU vitamin D while pregnant did not help much (no surprise) – RCT
• Zinc cut in half the rate of prediabetes progressing to diabetes (20 mg) – RCT
• Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT
• Preeclampsia risk reduced by higher levels of vitamin D (VDAART 4,400 IU) - RCT
• Cognition of Alzheimer’s patients improved by daily 4,000 IU of vitamin D – RCT
• Vitamin D response time is 3-6 months, not much benefit in first 4 months – RCT
• Rickets virtually cured by 90,000 IU of Vitamin D along with daily Calcium – RCT
• 2000 IU vitamin D during pregnancy and 800 IU to infant resulted in less use of antibiotics – RCT
• Insulin problems reduced by Curcumin if not also take Omega-3 – RCT
• Should increase Vitamin K when increasing Vitamin D – RCT
• Fat loss, etc. if respond well to 3 years of Vitamin K2 (MK-7, 180 ug) – RCT
• Common cold incidence reduced by two thirds (500 IU for IBD with low vitamin D) – RCT
• 100,000 IU of vitamin D monthly decreases use of NASIDs by 13 percent if low vitamin D – RCT
• Omega-3 supplements taken before and after surgery actually helped – RCT
• 4000 IU Vitamin D Safe and Effective For Healthy Pregnant Women – RCT
• 3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT
• Prediabetics not helped by weekly vitamin D (perhaps D2) – RCT
• PMS reduced by half in girls who had low levels of vitamin D – RCT
• Black infant recurrent wheezing rate dropped from 42 percent to 31 percent with just 400 IU of vitamin D – RCT
• Depression probably treated by bi-weekly 50,000 IU of vitamin D - RCT 2020
• Poor blood-brain barrier following stroke if low vitamin D (in rats) – RCT
• IBS – 82 percent had low vitamin D, 3,000 IU spray helped a lot – RCT
• Physical performance of black senior women not improved with 30 ng of Vitamin D – RCT
• 50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014
• Senior quality of life not helped by 800 IU of Vitamin D (not nearly enough) – RCT
• Omega-3 added during pregnancy helps in many ways – Cochrane Review of RCTs
• Nordic Walking and 4,000 IU of vitamin D lowered cholesterol, fat, weight, and lipids (senior women) – RCT
• Gestational Diabetes reduce 3 times by 5,000 IU of Vitamin D – RCT
• Omega-3 reduced vitamin D3 inflammation for obese – RCT
• Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT
• Vitamin D increased Phosphorus absorption (chickens) – RCT
• Cognition improved a tiny amount with 400 IU of vitamin D (not a surprise) – RCT
• Farmed fish not have enough vitamin D to increase levels – RCT
• 100000 IU vitamin D monthly helps COPD patients – 3 RCT
• 1200 mg is too much Calcium for seniors if take 4,000 IU of vitamin D – Oct RCT 2018
• Obese youths 2X less likely to develop Metabolic Syndrome if take Omega-3 – RCT
• Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT
• Knee Osteoarthritis benefited by 20 ng of Vitamin D for 5 years – RCT
• Bone STRENGTH improved by 2800 IU of Vitamin D (not bone density) – RCT
• Falls reduced by a third if achieved 40 ng level vitamin D– RCT
• Increased Bone strength during military training – with just 800 IU of vitamin D and Calcium – RCT
• Skin whitening cream (RD) may cause blotchy skin, 5,000 Vitamin D can treat it – RCT
• 2,000 IU of Vitamin D is not enough to maintain levels above 30 ng – RCT
• Many health risks associated with low Vit D or poor Vitamin D Receptor – more RCT needed
• Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT
• Chronic Periodontitis reduced by Omega-3 – RCT
• Lung cancer treated by Vitamin D (1200 IU early stage) – RCT
• 5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT
• Adding just vitamin D again failed to add bone density (also need Magnesium, Vitamin K, etc) – RCT
• Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT
• Vitamin D RCT using 100,000 IU monthly for a variety of health problems – results of ViDA due in 2016
• Breast milk resulted in 20 ng of vitamin D for infant if mother had taken 5,000 IU daily – RCT
• Vitamin D RCT – control to get same dose, but delayed by 1 month – 2020
• PCOS treated by a combination of Vitamin D and Omega-3 – RCT
• Knee replacement not helped by 2,000 IU of vitamin D (both too late and too little) – RCT
• Seniors getting Vitamin D (but no exercise) for 3 months failed to increase muscle strength – RCT
• 1200 IU vs 400 IU of vitamin D did not improve bone health or immunity of children who were sufficient – RCT
• Adding Vitamin D, Omega-3, etc to children’s milk improved memory (yet again) – RCT
• Teen dancers had 3X fewer traumatic injuries after 120,000 IU Vitamin D over a week – RCT
• Depression – is it reduced by Vitamin D and or Omega-3 – RCT 2019
• Just 400 IU of daily Vitamin D reduced miscarriage (recurrent) by 3.5 times – RCT
• Omega-3 reduced aggressive incidents in prisoners by 30 percent – RCT
• Psychosis risk reduced for 80 weeks by just 12 weeks of Omega-3 – RCT
• Fibromyalgia pain reduced with vitamin D intervention that achieved 30-48 ng – RCT
• Insulin sensitivity in obese adolescents greatly improved with 4000 IU of vitamin D - RCT
• Omega-3 for just 3 months greatly reduced psychosis for 80 months – RCT
• Multiple sclerosis helped some by 10,000 IU of vitamin D daily avg. for 3 months – RCT
• IBS quality of life improved by vitamin D (50,000 IU every two weeks) – RCT
• Cystic fibrosis treatment by vitamin D improved quality of life and breathing (8200 IU daily)– RCT
• Gestational Diabetes treated with 50,000 IU every two weeks – RCT
• No genetic response to 4,000 IU of Vitamin D (other studies disagree) – RCT
• Urinary sepsis – a single Vitamin D injection reduced hospital days by 40 percent – RCT
• Ethical Quandary – give Vitamin D to all in RCT
• Is 4000 IU the best Vitamin D dose for seniors – RCT underway
• Infants getting up to 1600 IU did not increase blood level of vitamin D – RCT
• Open Heart Surgery associated with low vitamin D, but not if 150,000 IU before surgery – RCT
• People felt less aggression after just 6 weeks of Omega-3 – RCT
• Sickle Cell clinical trial will inject 300,000 IU of vitamin D – RCT due 2020
• Omega-3 supplement better than farmed salmon at raising Omega-3 index – RCT
• BMI reduced by Vitamin D (not much reduction – only got VitD to 26 ng) – RCT
• ADHD reduced by just 3,000 IU of Vitamin D and methylphenidate for just 12 weeks – RCT
• 35,000 IU vitamin D weekly during 3rd quarter pregnancy – RCT
• Elite Athletes do well with weekly 35,000 IU of Vitamin D – RCT
• Muscle strength not increased by raising vitamin D to only 30 ng – RCT
• Vitamin K-2 (180 ug MK-7) helped both bone density and strength – RCT
• Extreme preterm infants need a total of 1,000 IU of vitamin D daily – RCT
• Low-dose statin plaque formation stopped by Omega-3 – RCT
• Rickets in half of premature births – 200 IU of vitamin D is enough – RCT
• Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT
• Magnesium (300 mg daily) improved physical performance of senior women – RCT
• Clinically Isolated Syndrome progresses to Multiple Sclerosis, unless UVB treatments – RCT
• Amyotrophic Lateral Sclerosis patients helped by Omega-3 – RCT
• Dry eye treated equally well by Omega-3 and krill oil – RCT
• Omega-3 reduced dry eye (computer related) by 3X - RCT
• Breathing by ever-smokers improved by monthly Vitamin D – RCT 2017
• Arterial stiffness reduced by a single dose of 100,000 IU of vitamin D – RCT
• Lupus reduced when half of participants got to 38 ng of Vitamin D (not statistically significant) – RCT
• 800 IU of vitamin D got most white Danish children to 20 nanograms – RCT
• Prostate Cancer might be treated by 4,000 IU of vitamin D and aspirin – RCT 2021
• Colon Cancer proven again to not be treated by just 1000 IU of vitamin D – RCT
• Cognitively impaired brain atrophy was slowed 40 percent by Omega-3 and B vitamins – RCT
• Senior cognition improved somewhat by 4,000 IU of Vitamin D (if initially less than 30 ng) – RCT
• Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT
• Atopic Dermatitis (Eczema) in Mongolian children reduced with 1,000 IU of vitamin D – RCT
• Heart Failure Quality of Life greatly improved by 10,000 IU of vitamin D – RCT
• Blood pressure reduced by monthly 100,000 IU of vitamin D in those who were deficient – RCT
• Bone loss not stopped by monthly 48,000 IU of vitamin D – RCT
• Multiple Sclerosis stem cell treatment (HSCT) probably not benefit from 200,000 IU of vitamin D – RCT 2020
• Leg bone (tibia) grew thicker with 4,000 IU of vitamin D and Calcium – RCT
• Probably Fractures of the Tibia can be healed with 100,000 IU of vitamin D weekly – RCT 2023
• Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019
• Delay onset of Multiple Sclerosis with 100,000 IU of vitamin D every two weeks – RCT 2020
• Perhaps fewer bone non-unions with 100,000 IU weekly of vitamin D – RCT 2018
• Transdermal Magnesium cream worked for non-athletes– RCT
• Hypertension not reduced by adding vitamin D to patients who had enough vitamin D – RCT
• Children helped by 2,000 IU of vitamin D, but not RDA amount (600 IU) – RCT
• Preemies need 1,000 IU of vitamin D – RCT
• Vitamin D aided progesterone in reducing traumatic brain injury – RCT
• Falls and vitamin D – another poor study – RCT
• 2000 IU of vitamin D should improve toddlers health in winter – RCT almost completed
• More than 5X increase in activation of scores of genes for women with Vitamin D (20,000 IU weekly) RCT
• Monthly 120,000 IU Vitamin D plus daily Calcium was great during pregnancies – RCT
• Semi-activated vitamin D (HyD3) successfully being used in human trials – RCT
• Reduced depression with single 300,000 IU injection of vitamin D – RCT
• Lung bacteria decreased by 1,000 IU of vitamin D (only in non-smokers) – RCT
• Estrogen contraception pill doubled the response to 1,000 IU of vitamin D – RCT
• Response to 1000 IU of vitamin D varies by about 4 percent due to gene variants – RCT
• Bones helped by Vitamin D, Physical Exercise, etc (this time - Bariatric Surgery) – RCT
• Diabetes not treated by single dose of vitamin D – RCT
• Anemia (in heart failure) not treated by Vitamin D (they should have added Iron) – RCT
• Obese helped with resistance training by 4000 IU of vitamin D – RCT
• Violent schizophrenia patients treated by 3 months of Omega-3 – RCT
• Advanced Colon Cancer risk is doubled or halved with 1000 IU of Vitamin D, depends on Vitamin D Receptors – RCT
• Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT
• Cervical lesions (precancerous, identified by pap smear) treated by bi-weekly 50,000 IU of vitamin D – RCT
• Muscle strength not increased by Vitamin D - 96 percent were not deficient – RCT
• Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT
• Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT
• Near the end of pregnancy 50,000 IU vitamin D weekly was great – RCT
• Hives treatment augmented by 60,000 IU Vitamin D weekly – RCT
• Vitamin D daily or weekly dosing resulted in similar response -RCT
• Prenatal Vitamin D (35,000 weekly, 3rd trimester) resulted in 1 cm taller infants at age 1 year – RCT
• 50,000 IU of vitamin D weekly (D3 or D2) got two thirds of cystic fibrosis patients to 30 nanograms – RCT
• Juvenile Lupus fatigue reduced by vitamin D ( 50,000 IU weekly for 6 months) – RCT
• Non-alcoholic fatty liver disease (NAFLD) reduced somewhat by 50,000 IU vitamin D every 2 weeks – RCT
• No multiple sclerosis relapses during pregnancy if 50,000 IU of Vitamin D weekly – RCT
• 2X fewer Senior falls in group getting 100,000 IU vitamin D monthly via Meals-on-Wheels – RCT
• Weekly pizza fortified with 28,000 IU raised Vitamin D by 30 nanograms – RCT
• Pregnancy – adding 35,000 IU Vitamin D weekly was nice, but not enough – RCT
• Many benefits of 50,000 IU vitamin D every two weeks (methadone treatment) – RCT
• Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – RCT
• Preeclampsia recurrence reduced 2 X by 50,000 IU of vitamin D every two weeks – RCT
• Breast Density and Cancer not reduced by Vitamin D (only used 3,000 IU) - RCT
• Fertility marker (Anti-Müllerian Hormone) improved in a week by a single dose to 50,000 IU of vitamin D – RCT
• Bone health not improved in 2 months of Vitamin D (need 6 months or loading dose) – RCT
• Off topic: Insulin spike cut in half if take 1 tablespoon of extra virgin olive oil with meal – RCT
• Long-term lower back pain greatly reduced by Magnesium - RCT 2013
• Cystic Fibrosis RCT to use 250,000 IU of vitamin D
• Heart Failure not helped by Vitamin D (several strange things about the trial) – RCT
• Spray and oral forms of 3000 IU vitamin D provide similar long-term response – RCT
• Teens able to think better after vitamin D levels raised to just 25 nanograms – RCT
• Modeling Cancer RCTs – including Breast Cancer
• Directly Observed Vitamin D therapy is one of many ways to increase compliance – RCT
• Vitamin D loading dose after hip fracture surgery was great – RCT
• Why 100,000 IU of vitamin D monthly did not reduce Cardiovascular Disease – RCT
• Single dose (up to 60,000 IU) vitamin D raised levels in 87 percent of Cystic fibrosis patients – RCT
• Testosterone increased 20 percent with daily 3332 IU vitamin D – RCT
• Infants getting 1 g of Omega-3 for 12 weeks got better brains – RCT
• Bone mineral density somewhat better with 3750 IU vs 600 IU Vitamin D (1 year, with Calcium) – RCT
• 300,000 IU of vitamin D injection not enough to statistically reduce markers of Venous Thromboembolism – RCT
• Tuberculosis treatment greatly helped by injection of 200,000 IU of vitamin D – RCT
• Visual memory improved a bit by vitamin D if start with less than 30 ng – RCT
• Pregnant women were 2.6 times more likely to stop smoking when given financial rewards – RCT
• Severely burned children recovered muscle capability much faster with daily 1000 IU of vitamin D – RCT
• Fatigue reduced by a single dose of vitamin D (100,000 IU) – RCT
• Crohn's disease treated by 2000 IU Vitamin D - RCT
• Critically ill injected with 300,000 IU of vitamin D, 3X more likely to die if PTH did not respond - RCT
• Multiple Sclerosis Relapsing-Remitting rate reduced 30 percent by addition of 14,000 IU vitamin D daily – RCT
• Vitamin D intervention increased by 20 percent the survival of critically ill patients- RCT
• Leg cramps in pregnant women not changed by 1,000 IU of vitamin D for 6 weeks (no surprise) – RCT
• 3,800 IU Vitamin D during pregnancy did not help much – RCT
• Overweight and obese lost 12 lbs with vitamin D in 6 months– RCT
• Asthma reduced 31 percent when Omega-3 taken during pregnancy – RCT
• Indoor bicycling and 2000 IU of vitamin D lowers heart rate by 6 percent – RCT
• Elderly falls reduced 3.6 times by 900 IU of vitamin D and simple exercise – RCT
• Pneumonia in children not stopped for 6 months by single dose of vitamin D (3 months max) – RCT
• How vitamin D helps exercise (IGF) – RCT
• Preeclampsia 3.5 times more likely if low vitamin D (affects 348 Vit. D genes) – RCT
• Physical Function of sedentary seniors not helped by vitamin D (for several reasons) – RCT
• Winter youths need at least 1200 IU of vitamin D to maintain 20 nanograms – RCT 2016
• Improved muscle function in postmenopausal women with just 1,000 IU of vitamin D daily – RCT
• 3000 IU of Vitamin D – not much difference between capsule and spray – RCT
• Cancer risk in older women reduced 32 percent by 2,000 IU of Vitamin D plus Calcium – 4 year RCT
• Diabetes not treated by 28,000 IU of weekly vitamin D (proven again) – RCT
• COPD reduced by 40 percent with monthly 100,000 IU of vitamin D – RCT
• Bone fractures after a burn - none if vitamin D, 6 if no vitamin D – RCT
• Gestational Diabetes reduced 40 percent by 5,000 IU of vitamin D – RCT
• Perinatal depression decreased 40 percent with just a few weeks of 2,000 IU of vitamin D – RCT
• Obese need more Vitamin D: Volume dilution, IU per pound, or BMI – RCT
• Obese need 2.5 IU of vitamin D per kg to increase 1 ng (about 3.4 X more) – RCT
• Most Olympic-class Dutch athletes nudged Vitamin D levels above 30 nanograms with 2200 IU daily – RCT
• Sunscreen used daily vs discretionary: no difference in skin cancer rate – RCT 2016
• Childhood asthma still reduced 4 months after 800 IU of Vitamin D daily - RCT
• Tanning bed twice a month slightly increased vitamin D levels during the winter – RCT
• Decreased need for warfarin after Vitamin D levels optimized – RCT
• Zinc helps pregnancies – 14 percent fewer preterm births, etc. – Cochrane RCT
• Just 1500 IU of Vitamin D significantly helps Prozac – RCT
• Magnesium oxide is (surpringly) better than citrate – RCT
• Vitamin D improved child muscle mass even without varying dose with weight – RCT
• Five times less mite allergy when vitamin D added in mid pregnancy and to infant – RCT
• Infant much healthier if Gestational Diabetic mother got 2 doses of vitamin D – RCT
• 800 IU vitamin D for infant and 2000 IU for mother is good, not great – RCT
• Youths need 1500 IU to get even 20 ng of vitamin D – RCT
• Knee osteoarthritis reduced somewhat by 50,000 IU vitamin D monthly (need more) – RCT
• Staph infections with eczema reduced with 2,000 IU of vitamin D – RCT
• 5X fewer school days missed due to asthma if take 2,000 IU vitamin D daily – RCT
• More calcium in bones in those teenage girls getting 2,000 IUs daily – RCT
• Gestational Diabetes helped by Vitamin D and Calcium (also less C-section and LGA) – RCT
• Gestational diabetes – Vitamin D and Calcium provided huge benefits – RCT
• Rate of falls reduced 2X by just 1000 IU of vitamin D – RCT
• Inflammation in African Americans not reduced with 3 months of 4000 IU of vitamin D – RCT
• Overweight women on caloric restriction diet got 3X benefits from 8 weeks of Omega-3 – RCT
• Back pain not relieved when vitamin D levels remained below 30 nanograms – RCT
• Depression not reduced when vitamin D levels less than 30 nanograms – RCT
• Schizophrenia treated by 6 months of Omega-3 – RCT
• Seasonal affective disorder not treated by 2800 IU of vitamin D (no surprise) – RCT
• Improved births with 2,000 IU vitamin D during pregnancy in India - RCT
• Vitamin D during pregnancy increases infant levels for two months – RCT
• Musculoskeletal pain reduced with 4,000 IU of vitamin D – RCT
• Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT
• 5,000 IU Vitamin D was not enough to reduce preeclampsia but did help future infant – RCT
• Colds not decreased if people already vitamin D sufficient – RCT
• Respiratory diseases helped by vitamin D if initially have low level – RCT review
• MRI (perhaps 400 hours) cut vitamin D levels of rats in half - RCT
• Gestational diabetes reduced by just two 50,000 IU doses of vitamin D – RCT
• Hypertension reduction sometimes needs more than 4,000 IU of vitamin D for 6 months – RCT
• Post menopausal vaginal dryness treated with vitamin D vaginal suppositories – RCT
• Monthly 100,000 IU vitamin D supplementation got virtually all vitamin D deficient subjects above 20 ng – RCT
• Vitamin D given once every two months does not help – proven again – RCT
• Rate of injuries from falls cut in half by just 800 IU of vitamin D and exercise – RCT
• 39% fewer falls with 2000 IU than 800 IU – RCT
• Schizophrenia relapses reduced 3X by Omega-3 – RCT
• Will knee osteoarthritis be prevented with 1700 IU of vitamin D – proposed RCT
• Volleyball players jump higher with Magnesium - RCT 2014
• Vitamin D2 from cooked mushroom added virtually no vitamin D to bloodstream - RCT
• Pain not reduced by vitamin D (only used 1,000 IU) - RCT
• Diabetes RCT we expect to fail just 50,000 IU monthly
• Monthly vitamin D (120,000 IU) got most overweight African Americans about 35 ng – RCT
• 1000 IU vitamin D not enough in winter to restore levels in children - RCT
• Postoperative adhesions reduced in rats supplemented with vitamin D – RCT
• COPD reduced by vitamin D taken once every 60 days – RCT
• CYP2R1 gene probably responsible for low vitamin D response – RCT
• 400 IU Vitamin D did not affect menopause (400 IU affects virtually nothing) - RCT
• Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT
• Diabetes decreased with 300 mg of Mg (Mg Sulfate) – RCT
• Off topic: Large dose of Vitamin A increased allergic reaction in girls by 1.8X – RCT
• Age-related cognitive decline in rats mitigated by Vitamin D intervention – RCT
• Breast Cancer is prevented by vitamin D – but more RCT are needed to understand why
• Asthma not reduced by taking vitamin D every 60 days (no surprise) – RCT
• Tuberculosis not treated by 7,000 IU Vitamin D daily average for 6 weeks – RCT
• Probability of getting TB reduced 60 percent with just 800 IU of vitamin D – RCT
• Following primary hyperparathyroidism surgery 1600 IU vitamin D was not enough to help - RCT
• Lupus not treated by monthly 50,000 IU vitamin D (no surprise) – RCT
• Heart failure markers reduced by 400 IU of vitamin D and Calcium (surprise) – RCT
• Death due to cystic fibrosis reduced about 4X due to 250000 IU of vitamin D – RCT
• Cystic fibrosis helped with single dose of 250,000 IU of vitamin D – RCT
• 3000 IU reduced hypertension for the vitamin D insufficient – RCT
• MS helped by average daily 2800 IU vitamin D – RCT
• 1600 IU vitamin D was enough to get all (white, non-obese) elderly to 20 ng – RCT
• Hip bone loss stopped with 1000 IU of vitamin D, while 400 IU similar to placebo – RCT
• Many preemies need at least 800 IU of vitamin D – RCT
• Hip fracture reduced 38 percent with Calcium and just 400 IU of vitamin D – RCT
• More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT
• Calcium and 4,000 IU Vitamin D in Postmenopausal Women – RCT
• Bronchial Asthma reduced with 60,000 IU monthly vitamin D – RCT
• Hip fractures reduced 2X to 6X with just 10 minutes of sunlight daily – RCT 2003-2010
• 6 percent less likely to die by taking just a little vitamin D for 3 plus years – RCT
• 2800 IU of vitamin D before and after parathyroid surgery helped a lot – RCT
• 4000 IU vitamin D daily for just 5 days reduced inflammation after heart attack – RCT
• Hypertension reduced 6.8 mmHg with 3,000 IU of vitamin D daily – RCT
• Infants getting 1400 IU vitamin D weekly grew better – RCT
• Women taking 4,000 IU reduced pregnancy risks in half RCT
• TB treatment helped with Vitamin D – RCT
• Pregnancy helped by single dose of 60,000 IU of Vitamin D – RCT
• Vitamin D2 DECREASED blood levels of Vitamin D3 by 12 ng – RCT
• Vaginosis not reduced by average of 2800 IU vitamin D daily – RCT
• Adding 4,000 IU of vitamin D daily at 20 weeks pregnancy not help much – RCT
• Muscle increased 17 percent in vitamin D insufficient elderly getting 4,000 IU for 4 months – RCT
• 7000 IU of vitamin D restored most HIV youths to above 32 ng - RCT
• T2 Diabetes helped by aerobic exercise, adding 1200 IU vitamin D helped even more – RCT
• Calcium in blood (tightly regulated) did not increase when increase vitamin D to 40 ng – RCT
• People with old burns improved muscle strength with 2200 IU average vitamin D – RCT
• Probiotic (L. reuteri NCIMB 30242 ) greately increased vitamin D levels for many – RCT
• Increasing vitamin D level in blood failed to decrease Fatty Liver inflammation – RCT
• Just 300 IU daily of vitamin D reduced respiratory infections by 50% – RCT
• Recent Diabetics treated by supplementation which achieved 60 ng of vitamin D – RCT
• Allergy to House dust mite greatly reduced by adding just 600 IU of vitamin D – RCT
• 1600 IU daily Vitamin D raised adult blood levels above 20 ng – RCT
• Immune System response of infants is associated with higher levels of vitamin D – RCT
• How to predict response to a vitamin D dose – RCT
• Obese may need 40 percent more vitamin D - RCT
• 1700 IU vitamin D for a year provided no cardiovascular benefit (no surprise) – RCT
• 4000 IU RCT reduces type 2 diabetes HOMA by 24% and CRP by 64%
• Daily Magnesium improved all aspects of metabolic profile – RCT
• Dark skinned in Norway: 1000 IU vitamin D not enough to reduce pain – RCT
• 150,000 IU vitamin D reduced pain in immigrants – RCT
• Diabetes prevention RCT kicked off: adding 4,000 IU vitamin D
• Even taking as much as 4200 IU vitamin D 43 percent had less than 30 ng in blood – RCT
• Maternal vitamin D: slight differences between daily vs single doses – RCT
• Proven yet again – more than 500 mg of Calcium can be a problem – RCT
• Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT
• 20 cent vitamin D pill similar to 2 hours sunbathing at 60 degree latitude – RCT
• Bones better after pregnancy with just 200 IU of vitamin D plus 600 Calcium – RCT
• Need at least 800 IU of vitamin D for 6-12 months – meta-regression analysis of RCT
• Vitamin D needed for many months to reduce blood pressure – RCT
• Not enough vitamin D in milk to reduce hypertension (no surprise)– RCT
• Mayo clinic starting Cancer RCT using grossly inadequate 2,000 IU of vitamin D
• Probiotic (Lactobacillus reuteri) increased vitamin D levels 22 percent – RCT
• Vitamin D for older people (VDOP) trial, with 48,000 IU per month – RCT started Fall 2012
• Girls in India grew much faster when given Vitamin D, Ca, Zn, multi. – RCT
• 1000 IU of vitamin D not enough to increase teen blood levels – RCT
• 2000 IU vitamin D raised virtually all Lebanese youths above 20 ng – RCT
• Off topic: 4G cellphones - just 30 minutes causes change in brainwaves - RCT with sham
• Both Vitamin D and Calcium are needed to reduce bone loss – RCT
• Vitamin D3 increased and Vitamin D2 decreased the D3 serum levels – RCT
• 800 IU and 20 ng is enough vitamin D, need RCT
• Even with 400 IU of vitamin D in winter, 1 in 6 were still vitamin D deficient – RCT
• 400 IU of vitamin D for infants is good, 200 IU is not enough – RCT
• Tanning bed not improve vitamin D levels for a type of pancreatitis – RCT
• 2400 IU raised both black and white women to 40 ng of vitamin D – RCT 2013
• Needed more than 1600 IU of vitamin D during pregnancy – RCT
• Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT
• Can take 40,000 IU of vitamin D daily before prostate cancer surgery – RCT
• South Asians in UK get little vitamin D from 45 minutes of daily summer sun – RCT
• Insulin improvement in obese teens with 4000 IU of vitamin D – RCT
• 2000 IU of vitamin D for just 5 days did not treat severe pneumonia – RCT
• Vaccine and 1000 IU of vitamin D started concurrently, vitamin D did not help – RCT
• Rosuvastatin given for renal problem resulted in increased vitamin D levels – RCT
• Lost more weight on low calorie diet if add 600 mg Ca and just 150 IU vitamin D – RCT
• Type II Diabetes not reduced by 3 months of 5000 IU of vitamin D – RCT
• 1000 IU of vitamin D reduced child PTH, but did not increase Calcium – RCT
• Vitamin D less than 3000 IU insufficient to reduce MS relapse rate – 5 RCT
• RCT confirms that Australians need at least 2000 IU vitamin D
• Vitamin D Supplementation and Cancer - Review of RCT
• Osteoporosis medicine teriparatide increased active vitamin D by 25 pcnt– RCT
• Just 500 IU of vitamin D helped reduce rheumatoid arthritis pain - RCT
• Will 10000 IU of vitamin D decrease MS - RCT
• UV every two weeks maintains summer vitamin D level – RCT
• Calcium absorption increased only 6 percent for high amounts of vitamin D – RCT
• Vitamin D and Calcium best to prevent falls – RCT 2009
• 800 IU vitamin D is enough to help Whole Body Vibration – RCT
• Calcium and vitamin D aided weight loss – RCT