RCTs: The Foundational Flaw of Modern Medicine? - Cheng

GrassrootsHealth Nov 2025

Written by Dr. Richard Z. Cheng,

Key Points

  • RCTs were designed for drugs, not nutrition or lifestyle, so they often fail to capture the complexity of real-world health and individualized biology.
  • Human health is multifactorial, and reductionist RCT methods oversimplify diverse genetics, nutrient status, and environmental factors—producing results that may not reflect real clinical outcomes.
  • Statistical significance is prioritized over meaningful patient improvement, allowing marginal drug benefits to be celebrated while dismissing real-world successes of nutrition-based therapies.
  • Many important health interventions (vitamin D, vitamin C, niacin, ketogenic diets, detoxification) cannot be properly evaluated using traditional RCT methods, making RCT dogma a barrier to truly evidence-based, patient-centered medicine.