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Recurrent RTI treatment success: Conventional 71 pcnt, Vitamin D 96 pcnt – March 2021

The immunomodulatory effects of vitamin D drops in children with recurrent respiratory tract infections

Am J Transl Res. 2021 Mar 15;13(3):1750-1756. eCollection 2021.
Jianqiu Xiao 1, Wei He 1
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Objective: To investigate the effects of vitamin D drops on immune function in children with recurrent respiratory tract infections (RRTI).

Methods: The clinical data of 119 children with RRTI in our hospital were retrospectively retrieved, and they were divided into group A (n=59, receiving routine treatment) and group B (n=60, receiving vitamin D drops) based on their treatment modality. The clinical efficacy, symptom disappearance time, immune function index, insulin-like growth factor (IGF-1), 25-hydroxyvitamin D3 [25-(OH)D3], serum y-interferon (INF-y), and the number of episodes of respiratory tract infections were compared between the two groups.

Results: The total effective rate of treatment in group B was 96.67%, which was significantly higher than 71.19% in group A (P<0.05).
Children in group B had shorter time to disappearance of lung rales, cough, and fever than group A (P<0.05).
Group B had higher IgA, IgG, and IgM levels, higher CD4+, CD3+ levels and lower CD8+ levels as well as higher IGF-1, 25-(OH)D3, INF-y levels, and fewer respiratory infections after treatment than group A (P<0.05).

Conclusion: Vitamin D drops are effective in the treatment of children with RRTI, which is beneficial to the improvement of clinical symptoms and immune function.
Clipped from PDF
Group A: After admission, patients were given supportive therapy such as supplemental oxygen, cough suppressants, asthma and expectoration treatment according to their condition.

Group B: Vitamin D drops (H20113033, Qingdao Shuangjing Pharmaceutical Co., Ltd. 400 units * 10 tablets * 3 tablets) were taken orally at q.d 800 U. Twenty days of medication and 10 days without in every 30 consecutive days were a course of treatment, and a total of 3 courses were performed.
Appears to be 800 IU


VitaminDWiki
Infant-Child category has 634 items and starts with

Having a good level of vitamin D cuts in half the amount of:

Need even more IUs of vitamin D to get a good level if;

  • Have little vitamin D: premie, twin, mother did not get much sun access
  • Get little vitamin D: dark skin, little access to sun
  • Vitamin D is consumed faster than normal due to sickness
  • Older (need at least 100 IU/kilogram, far more if obese)
  • Not get any vitamin D from formula (breast fed) or (fortified) milk
    Note – formula does not even provide 400 IU of vitamin D daily

Infants-Children need Vitamin D

  • Sun is great – well known for 1,000’s of years.
    US govt (1934) even said infants should be out in the sun
  • One country recommended 2,000 IU daily for decades – with no known problems
  • As with adults, infants and children can have loading doses and rarely need tests
  • Daily dose appears to be best, but monthly seems OK
  • Vitamin D is typically given to infants in the form of drops
       big difference in taste between brands
       can also use water-soluable form of vitamin D in milk, food, juice,
  • Infants have evolved to get a big boost of vitamin D immediately after birth
    Colostrum has 3X more vitamin D than breast milk - provided the mother has any vitamin D to spare
  • 100 IU per kg of infant July 2011, Poland etc.
    1000 IU per 25 lbs.jpg
    More than 100 IU/kg is probably better

Getting Vitamin D into infants
Many infants reject vitamin D drops, even when put on nipple
I speculate that the rejection is due to one or more of: additives, taste, and oils.
Infants have a hard time digesting oils, 1999  1997   and palm oils W.A. Price 1 2 3
Coconut oil, such as in D-Drops, is digested by infants. 1,   2   3
Bio-Tech Pharmacal Vitamin D has NO additves, taste, oil
One capsule of 50,000 Bio-Tech Pharmacal Vitamin D could be stirred into monthly formula
   this would result in ~1,600 IUs per day for infant, and higher dose with weight/age/formula consumption

Items in both categories Breathing and Infant-Child:


Created by admin. Last Modification: Monday April 12, 2021 19:46:05 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
15421 RRTI.jpg admin 12 Apr, 2021 19:16 28.44 Kb 21
15420 RRTIpdf.pdf PDF 2021 admin 12 Apr, 2021 19:10 616.11 Kb 3
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