Pediatric Allergy, Immunology, and Pulmonology. June 2017, 30(2): 86-91. https://doi.org/10.1089/ped.2017.0750
- Less Pneumonia in those having more activated vitamin D (kidneys working)– April 2014
- Search VitaminDWiki for pneumonia 508 hits as of June 2017
- Pneumonia acquired in hospital – 3X more likely to die if low vitamin D – June 2015 seniors
- Children with pneumonia in Ethiopia were 22X more likely to have rickets – 1997
Both are associated with low vitamin D
Low vitamin D in children is associated with a wide range of breathing problems
- Black infant recurrent wheezing rate dropped from 42 percent to 31 percent with just 400 IU of vitamin D – RCT Dec 2018
- Asthma in child 2.3 X more likely if both parents asthmatic (unless add Vitamin D) – VDAART Nov 2018
- Immature lungs in immature newborns – Vitamin D helps – Sept 2018
- Bronchiolitis had 1.3 X longer hospitalization if low Vitamin D (1016 infants) – Sept 2018
- Pneumonia in Egyptian Children 3.6 X more likely if poor Vitamin D Receptor – Aug 2018
- Childhood pneumonia not treated by 100,000 IU of vitamin D – Cochrane (need more, inhaled) – July 2018
- Pneumonia is increasing (now 1 in 6 child deaths), more vitamin D studies needed – June 2018
- Childhood Respiratory Health hardly improved with 600 IU of vitamin D (need much more) – May 2018
- Indoor pollution is a problem with obese black asthmatic children – May 2018
- Both parents smoke – child’s vitamin D level was 30 percent lower and worse asthma – May 2018
- Influenza -A infections half as often in children getting 1200 IU of vitamin D – RCT Jan 2018
- Rapid newborn breathing (transient tachypnea) associated with low vitamin D – Dec 2017
- Premature infants with poor lungs (Respiratory distress syndrome) have low levels of vitamin D – Nov 2017
- Risk of infant Asthma cut in half if mother supplemented Vitamin D to get more than 30 ng – RCT Oct 2017
- Respiratory infection in infant was 7 X more likely if low cord Vitamin D – March 2017
- Viral Pneumonia in children 52 X more-likely if very low vitamin D (trend) – June 2017
- Childhood asthma problems eliminated for months by 600,000 IU of Vitamin D – June 2017
- Childhood allergy, asthma and eczema associated with repeated low vitamin D tests – Oct 2016
- Childhood asthma about 1.3 times more likely if poor Vitamin D Receptor – meta-analysis Aug 2016
- Five times less mite allergy when vitamin D added in mid pregnancy and to infant – RCT April 2016
- Hay fever (allergic rhinitis) risk reduced 20 percent for each 100 IU of vitamin D during early pregnancy – Feb 2016
- Asthma in 3 year olds decreased somewhat with 4,000 IU during pregnancy – RCT Jan 2016
- Respiratory tract infections in childhood – vitamin D is needed, no consensus of how much – Oct 2015
- RSV (bronchitis and viral pneumonia) in infants associated with low vitamin D and antibiotics – Aug 2015
- Respiratory distress after preterm birth is more likely if low vitamin D – review April 2015
- All preemies with Chronic Lung Disease had low vitamin D levels– July 2015
- Low dose Vitamin D during pregnancy and infancy results in strange acute respiratory infection response – April 2015
- Newborn acute lower respiratory tract infection associated with low maternal vitamin D – March 2015
- Low vitamin D during pregnancy associated with four health problems in children – Jan 2015
- Low vitamin D at birth associated with later milk sensitization, allergic rhinitis and asthma – Nov 2014
- Acute Lower Respiratory Infections in Children - associated with low vitamin D – meta-analysis Dec 2014
- Respiratory Tract visits 2.5 less likely with vitamin D: Pregnancy 2000 IU, Infant 800 IU – RCT Oct 2014
- No premie had even 30 ng of vitamin D, lower D associated with more Respiratory Distress – Aug 2013
- Asthma is not treated by weekly 14,000 IU of vitamin D (proven yet again) July 2014
- 2000 IU of vitamin D should improve toddlers health in winter – RCT almost completed Feb 2014
- More Hypertension in obese children with low vitamin D, especially at night – Dec 2013
- Largest cause of infant deaths is respiratory infections, which is associated with low vitamin D – April 2011
- Vitamin D Deficiency is a Strong Predictor (4X) of Asthma in Children – Oct 2012
- Acute lower respiratory infection 5X more frequent with low vitamin D intake – June 2012
- Recurrence of child pneumonia delayed by 100000 IU of vitamin D – RCT Oct 2010
- Vitamin D Genes associated with Childhood Asthma And Lung Function - April 2012
- Allergy - Overview
- Severe asthma children 31X more likely to develop chronic obstructive lung disease -May 2010
Lin-Ying Guo, MD,1 Wei Li, MD,1 Xian-Fen Cheng, MD,2 Hong-Ri Li, MD,1 Chun-Rong Sun, MD,2 Jing Guo, MD,1 Guo-Wei Song, MD,1 Xiao-Dai Cui, MD,2 and Qi Zhang, MD1 zhangqi0355 at sina.com
1 Intensive Care Unit, Affiliated Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
2 Central Laboratory, Capital Institute of Pediatrics, Beijing, China.
This study investigated the impact of vitamin D status on the susceptibility and severity of viral pneumonia (VP) in children. A total of 236 children with VP, aged from 1 month to 14 years, and 271 gender and age matched healthy children to compare the serum 25(OH)D levels and vitamin D status. Vitamin D indices were compared between subgroups in VP cases. The median [interquartile range (IQR)] serum 25(OH)D level in these 507 children was 23.7 (IQR 17.5–30.6) ng/mL; 134 (26.4%) children were vitamin D sufficient [25(OH)D ≥30 ng/mL], whereas 373 (73.6%) were insufficient, which included insufficient [25(OH)D 20–30 ng/mL], deficient [25(OH)D 10–20 ng/mL], and severely deficient [25(OH)D ≤10 ng/mL]. The median (IQR) serum 25(OH)D level in the VP group was significantly lower than that in the control group [19.6 (12.3–26.4) ng/mL versus 26.6 (21.4–32.9) ng/mL] (P < 0.001).
The proportions of vitamin D deficiency (32.2% versus 19.5%) and severe deficiency (19.1% versus 0.4%) in the VP group were significantly higher than those in the control group (P < 0.001).
As vitamin D status decreased, the odds ratio (95% confidence interval) for VP showed an increasing trend [sufficiency (0.3; 0.2–0.5), insufficiency (0.9; 0.6–1.3), deficiency (2.0; 1.3–2.9), and severe deficiency (51.7; 7.2–372.2)].
The median (IQR) serum 25(OH)D level in the VP subgroup who accepted mechanical ventilation was significantly lower than that in the nonmechanical ventilation subgroup [12.9(6.5–22.5) ng/mL versus 20.8 (14.2–28.0) ng/mL] (P < 0.001).
Poor vitamin D status might be related to the susceptibility and severity of VP in children.