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Rapid newborn breathing (transient tachypnea) associated with low vitamin D – Dec 2017

Maternal and neonatal vitamin D deficiency and transient tachypnea of the newborn in full term neonates

Online: 2017-12-21 | DOI: https://doi.org/10.1515/jpm-2017-0280
Ahmed Omran, Heba Mousa, Mohamed Osama Abdalla, Osama Zekry

To investigate the association between maternal and neonatal serum 25-hydroxyvitamin D (25-OHD) levels and development of transient tachypnea of the newborn (TTN) in full term infants.

This was a prospective case-control study carried out on 30 neonates with TTN and their mothers and 30 control neonates and their mothers. Levels of 25-OHD were measured in maternal and neonatal blood samples that were obtained in the first 12–24 h of postnatal age.

Both maternal and neonatal 25-OHD levels in the TTN group were significantly lower compared to the control group (P=0.0001). A negative correlation was observed between neonatal 25-OHD level and average hospital stay (P=0.0001).

We observed that lower maternal and neonatal vitamin 25-OHD levels were associated with TTN development in full term infants.

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