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COVID fought by the antioxidants: Vitamin D, Zinc, Vitamin C, and Selenium – Review Sept 2022

Antioxidants and clinical outcomes of patients with coronavirus disease 2019: A systematic review of observational and interventional studies

Food Science & Nutrition https://doi.org/10.1002/fsn3.3034
Sahar Foshati, Fatemeh Mirjalili, Mahsa Rezazadegan, Farnoosh Fakoorziba, Reza Amani

Coronavirus disease 2019 (COVID-19) is a newly emerging viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Oxidative stress appears to be a prominent contributor to the pathogenicity of SARS-CoV-2. Therefore, we carried out a systematic review of human observational and interventional studies to investigate the role of some antioxidants such as vitamins A, E, D, and C, selenium, zinc, and α-lipoic acid in the main clinical outcomes of subjects with COVID-19. Google Scholar, Cochrane Library, Web of Science, Scopus, and Medline were searched using Medical Subject Headings (MeSH) and non-MeSH terms without restrictions.
Finally, 36 studies for vitamins C and D, selenium, and zinc were included in this systematic review; however, no eligible studies were found for vitamins A and E as well as α-lipoic acid.
The results showed the promising role of

  • vitamin C in inflammation, Horowitz index, and mortality;
  • vitamin D in disease manifestations and severity, inflammatory markers, lung involvement, ventilation requirement, hospitalization, intensive care unit (ICU) admission, and mortality;
  • selenium in cure rate and mortality; and
  • zinc in ventilation requirement, hospitalization, ICU admission, biomarkers of inflammation and bacterial infection, and disease complications.

In conclusion, it seems that antioxidants, especially vitamins C and D, selenium, and zinc, can improve multiple COVID-19 clinical outcomes. Nevertheless, more studies are necessary to affirm these results.
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VitaminDWiki pages with ANTIOXIDANTS in title (5 as of Feb 2023)

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Items found: 5

Vitamin D meta-analyses of Virus 33 studies

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VitaminDWiki Virus pages with ZINC in title (23 as of Sept 2022)

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Items found: 25
Title Modified
COVID ICU admission cut in half by twice-a-day Zinc- RCT Nov 2022 27 Dec, 2022
COVID fought by the antioxidants: Vitamin D, Zinc, Vitamin C, and Selenium – Review Sept 2022 14 Sep, 2022
COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells) 13 Apr, 2022
Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022 09 Apr, 2022
How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021 30 Jan, 2022
Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020 02 Jan, 2022
Florida A.G. recommends Vitamin D, Zinc, Quercetin, etc. to reduce risk of COVID - Dec 12, 2021 13 Dec, 2021
COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021 27 Sep, 2021
Observations that Vitamin D, Zinc, and Selenium separately reduce COVID-19 – Aug 7, 2020 16 Sep, 2021
Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021 20 Jul, 2021
COVID-19 risks reduced by Vitamin D, Magnesium, Zinc, Resveratrol, Omega-3, etc. (auto-updated) 19 Jul, 2021
How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021 04 Jun, 2021
COVID-19 treatment outside of hospital – Vitamin D, zinc, etc. – May 2021 12 May, 2021
Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021 06 May, 2021
Zinc therapy for COVID-19 – Feb 2021 19 Apr, 2021
Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018 03 Mar, 2021
Zinc (which increases vitamin D in tissues) may both prevent and treat COVID-19 15 Feb, 2021
Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021 28 Jan, 2021
COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020 09 Aug, 2020
7 reasons to think that Zinc should fight COVID-19 – July 2020 08 Aug, 2020
Mild COVID-19 quickly treated by Zinc lozenges in 4 people – June 6, 2020 29 Jun, 2020
Zinc, respiratory tract infections and COVID-19 – July 2020 07 Jun, 2020
Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020 14 May, 2020
Loss of smell may be related to low Zinc or perhaps low vitamin D 11 Nov, 2018
Dengue fever immune response and micronutrients (vitamins D, E, A, and Zinc, Iron, Chromium) – Nov 2015 11 Jun, 2016

VitaminDWiki - 25 studies in both categories Virus and Vitamin C

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VitaminDWiki Virus pages with SELENIUM in title (5 as of Sept 2022)

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Items found: 6

Created by admin. Last Modification: Wednesday February 1, 2023 20:56:45 GMT-0000 by admin. (Version 13)

Attached files

ID Name Comment Uploaded Size Downloads
18425 Types of anti-oxidents.jpg admin 13 Sep, 2022 23:08 99.52 Kb 149
18424 Antioxidants amd COVID.pdf PDF 2022 admin 13 Sep, 2022 23:08 991.15 Kb 48