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How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021


Nutritional risk of vitamin D, vitamin C, zinc, and selenium deficiency on risk and clinical outcomes of COVID-19: A narrative review

Clinical Nutrition ESPEN 47 (2022) 9-27 https://doi.org/10.1016/j.clnesp.2021.11.003
Lucia F.C. Pedrosa a’b’ , Acsa N.A.B. Barros a, Lucia Leite-Lais b
a Postgraduate Program in Health Sciences, Federal U. of Rio Grande do Norte, Natal, RN, 59078-970, Brazil
b Department of Nutrition, Federal University of Rio Grande do Norte, Natal, RN, 59078-970, Brazil

Number of studies found in PubMed
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The pathogenicity of the current coronavirus disease (COVID-19) shows postulates that optimal status of essential nutrients is crucial in supporting both the early viraemic and later hyperinflammatory phases of COVID-19. Micronutrients such as vitamin C, D, zinc, and selenium play roles in antioxidant, antiinflammatory, antithrombotic, antiviral, and immuno-modulatory functions and are useful in both innate and adaptive immunity. The purpose of this review is to provide a high-level summary of evidence on clinical outcomes associated with nutritional risk of these micronutrients observed in patients with COVID-19. A literature search was performed on PubMed and Google Scholar to obtain findings of crosssectional and experimental studies in humans. The search resulted in a total of 1212 reports including all nutrients, but only 85 were included according to the eligibility criteria. Despite the diversity of studies and the lack of randomized clinical trials and prospective cohorts, there is evidence of the potential protective and therapeutic roles of vitamin C, D, zinc, and selenium in COVID-19. The findings summarized in this review will contribute to guide interventions in clinical practice or in future clinical studies.
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Created by admin. Last Modification: Sunday January 30, 2022 16:51:37 GMT-0000 by admin. (Version 3)

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16946 Immune system and supplements.jpg admin 30 Jan, 2022 16:45 121.37 Kb 356
16945 Number of studies.jpg admin 30 Jan, 2022 16:44 7.01 Kb 320
16944 PIIS2405457721011074.pdf PDF 2021 admin 30 Jan, 2022 16:44 958.11 Kb 165