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Gestational Diabetes best fought by Vitamin D plus probiotics – RCT review Dec 2023


Advancements in Nutritional Strategies for Gestational Diabetes Management: A Systematic Review of Recent Evidence

J Clin Med . 2023 Dec 20;13(1):37. doi: 10.3390/jcm13010037.
Juan Carlos Sánchez-García 1 2, Ines Saraceno López-Palop 2, Beatriz Piqueras-Sola 1 3, Jonathan Cortés-Martín 1 2, Elena Mellado-García 1 4, Inmaculada Muñóz Sánchez 5, Raquel Rodríguez-Blanque 1 2 6

Gestational diabetes mellitus (GDM) is defined as hyperglycaemia first detected at any time during pregnancy with values lower than those determined by the WHO for diabetes diagnosis in adults. This pathology, with a worldwide prevalence of 13.4%, causes significant maternal and foetal risks. The first line of treatment consists of maintaining normo-glycaemia through an adequate diet and lifestyle changes. The aim is to synthesize the scientific evidence updating the nutritional recommendations for the effective management of GDM. A systematic review of the scientific literature was conducted following the PRISMA guidelines.
Randomized clinical trials published within the last five years and providing information on nutritional recommendations to achieve an effective management of gestational diabetes were selected. The databases searched were PubMed, the WOS Core Collection, SCOPUS, and CINAHL, using the MeSH terms: "Diabetes, Gestational"; "Nutrition Assessment (nutrition*)"; "Diet"; "Eating"; and "Food"; with the Boolean operators "AND" and "OR". The PEDro scale (Physiotherapy Evidence Database) was used to assess the scientific quality of the studies, with a mean score of 8.9, indicating an average good scientific quality.

Results: A total of 809 papers were collected, of which, after applying the inclusion and exclusion criteria, 14 randomized clinical trials were selected. Probiotic supplementation and co-supplementation with vitamin D have been found to be the most beneficial options for both mothers with GDM and neonates, but the most effective regimens are not known.
Diets enriched with extra virgin olive oil (EVOO) and oat bran, as well as some recommendations focused on carbohydrates also seem effective, as well as diets designed for this group of women with GDM such as "CHOICE".

Conclusions: Although there are numerous proposals that have been published in recent years focused on the diet of women with GDM in order to improve their results and those of their children, it is the supplementation with probiotics and the co-supplementation with vitamin D that is most agreed upon as beneficial; however, more research is needed into which protocols are most effective. Other proposals that could also be beneficial should be further studied.


VitaminDWiki - 44 studies in both categories Diabetes and Pregnancy

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33+ VitaminDWiki pages have PROBIOTICS in the title

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Items found: 33
Title Modified
Gestational Diabetes best fought by Vitamin D plus probiotics – RCT review Dec 2023 11 Jan, 2024
Feed Additives as Antiviral Agents: Probiotics, Vitamin D, Zn, Se, etc. - Dec 2023 31 Dec, 2023
Rheumatoid Arthritis should be prevented by improving gut microbiota (Vitamin D, probiotics, etc.) – March 2023 18 Mar, 2023
Autism may be synergistically treated by Vitamin D and probiotics – July 2022 27 Jul, 2022
COVID Long-Haul fought by probiotics - Jan 2022 29 Jan, 2022
Tested positive for COVID, taking probiotics stopped symptoms 5 days sooner - RCT Jan 2022 18 Jan, 2022
Probiotics augments Vitamin D – review of RCT Dec 2020 22 Jun, 2021
Microbiome improvement by probiotics can be augmented with phages (gut, etc.) 25 Feb, 2021
Vitamin D is aided by probiotics (review of RCTs) – Dec 2020 31 Jan, 2021
New drug application to FDA for a probiotic which might treat COVID-19 – Nov 19, 2020 20 Nov, 2020
Depression treated by Omega-3, Magnesium, Zinc, probiotics, etc - Sept 2017 08 Jan, 2020
Probiotics increased Vitamin D etc in healthy children – RCT Oct 2019 30 Oct, 2019
Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT Feb 2019 21 Feb, 2019
Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018 12 Jan, 2019
If struggling with mental health you may need Omega-3, Vitamin D. Iron, Probiotics, etc. – US News Sept 2018 11 Sep, 2018
Magnesium, Vitamin D, Omega-3, B12, Probiotics are the first of top 10 supplements for senior men - July 2018 21 Jul, 2018
Antibiotics, probiotics 22 Nov, 2016
Off topic: Consumer Labs has great reviews of supplements– a peek at their probiotics matrix 30 Jul, 2016
Hypothesis: vitamin D and probiotics will reduce type II diabetes – Jan 2013 03 Apr, 2016
Popular supplements 1 Vitamin D, 2 fish oil, 3 CoQ10, 4 multivitamins 5 probiotics - Feb 2016 27 Feb, 2016
Vitamin D receptor functionality improved with probiotics – Sept 2015 02 Sep, 2015
Probiotic and vitamin D synergy - July 2015 11 Jul, 2015
Colon cancer – vitamin D, probiotics, and leptin might help – May 2015 20 May, 2015
Probiotics reduces blood pressure, but not as much as vitamin D does – meta-analysis July 2014 01 Feb, 2015
Probiotic (L. reuteri NCIMB 30242 ) greately increased vitamin D levels for many – RCT July 2013 14 Dec, 2014
Probiotic (L. reuteri NCIMB 30242 ) increased vitamin D levels by 25 percent – RCT July 2013 26 Jul, 2014
Probiotic (Lactobacillus casei Zhang) reduces T2 Diabetes in mice – July 2014 26 Jul, 2014
Probiotics reduced weight gain in mice for many weeks (proof of concept) – June 2014 26 Jul, 2014
Probiotics, prebiotics, and the host microbiome - the science of translation – June 2013 21 Jul, 2014
Probiotic (Lactobacillus reuteri) increased vitamin D levels 22 percent – RCT July 2013 01 Dec, 2013
Probiotics increased vitamin D levels 22 percent in those with excess cholesterol – April 2013 21 May, 2013
Are microbs – probiotics – vitamin D – allergy – asthma – obesity related – Mar 2011 20 Jul, 2011
Many autistic children are getting some Vitamin D, Omega-3, probiotics, etc. - Aug 2019 No value for 'modification_date_major'