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Gestational Diabetes in 10 percent of pregnancies, vitamin D probably helps – Jan 2014

Vitamin D and gestational diabetes mellitus.

Curr Diab Rep. 2014 Jan;14(1):451. doi: 10.1007/s11892-013-0451-3.
Burris HH1, Camargo CA Jr.
1Department of Neonatology, Beth Israel Deaconess Medical Center, and Division of Newborn Medicine, Boston Children's Hospital and Harvard Medical School, 330 Brookline Avenue, RO 318, Boston, MA, 02215, USA, heburris at bidmc.harvard.edu.

Gestational diabetes mellitus (GDM) complicates 7 %-14 % of pregnancies in the United States. Vitamin D deficiency also is common in pregnancy. Emerging evidence suggests that Vitamin D administration can improve insulin sensitivity and glucose tolerance, but whether vitamin D supplementation can prevent GDM is unknown. Observational studies provide conflicting evidence as to whether low serum 25-hydroxyvitmain D (25(OH)D) levels are associated with GDM. Two recent systematic reviews concluded that vitamin D deficiency is associated with a higher risk of GDM. However, these reviews are limited by the observational and diverse nature of the included studies. Of greatest concern is the inability to understand how important confounding variables such as race/ethnicity and adiposity might affect the association. Randomized controlled trial data remain limited but are critical to understanding whether supplementation with vitamin D beyond what is contained in routine prenatal vitamins will prevent GDM or improve glucose tolerance for women with GDM.
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PMID: 24277676
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Pages listed in BOTH the categories Diabetes and Pregnancy in VitaminDWiki (a proxy for Gestational Diabetes)

Attached files

ID Name Comment Uploaded Size Downloads
5309 GDM trial.jpg admin 14 Apr, 2015 20:57 44.02 Kb 404
5308 GDM Jan 2014.pdf PDF 2014 admin 14 Apr, 2015 20:57 347.57 Kb 677
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