Arterial Stiffness and other cardiocascular problems have been proven to be reduced by supplementation by each of the nutrients which have decreased over the past 50 years. I do not know which is "best". Perhaps they work synergistically.
I personally take Vitamin D + Vitamin K + Omega-3 + Magnesium.
Henry Lahore, founder of VitaminDWiki
Table of contents
- Measure Arterial Velocity at home - $150 iPad (SW version: 3+), or iPhone (SW version: 4S+),Android (SW version: 5.0+)
- VitaminDWiki
- 120,000 IU Vitamin D monthly for 4 months ==> 10% better blood flow - RCT Nov 2017
- Items in both categories Cardiovascular and Omega-3 are listed here:
- Items in both categories Cardiovascular and Vitamin K-2 are listed here:
- Items in both categories Cardiovascular and Magnesium are listed here:
- See also web
Measure Arterial Velocity at home - $150 iPad (SW version: 3+), or iPhone (SW version: 4S+),Android (SW version: 5.0+)
I purchased a product to go with my iPad to measure my Arterial Velocity. Clips on the finger and makes the measurement in about 1 minute. Seems to be supported by good science. The iPad displays your realtive Arterial Velocity, etc. I have the Arterial Velocity of a person who is 20 years younger (51 instead of my actual 71)
https://goiheart.com/
VitaminDWiki
- Arterial stiffness reduced by vitamin D 4 studies
- Arterial stiffness reduced if use at least 2,000 IU of Vitamin D for 4 months – meta-analysis Dec 2019
- Arterial stiffness reduced by a single dose of 100,000 IU of vitamin D – RCT Dec 2014
- Stiff arteries in seniors associated with low vitamin D levels – July 2012
- 24X less Calcification of Aorta for PAD with modest level of vitamin D – Aug 2011
- Overview Hypertension and Vitamin D
- Hypothesis – Vascular calcification is associated with both too much and too little vitamin D - May 2018
120,000 IU Vitamin D monthly for 4 months ==> 10% better blood flow - RCT Nov 2017
Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial Dec 2017
 Download the PDF from VitaminDWiki
Items in both categories Cardiovascular and Omega-3 are listed here:
- Omega-3 reduces many aspects of heart problems - Jan 2024
- Cardiovascular problems reduced by Omega-3 - many studies
- Cardiovascular problems are prevented by Vitamin D plus Omega-3 – Feb 2023
- Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript - Dec 2021
- Atrial Fibrillation decreased by Vitamin D or Magnesium - many studies
- Omega-3 reduced cardiovascular deaths by 16 percent (427,678 people) – March 2020
- Synthetic EPA drug recommended to FDA for Cardio (Omega-3 is 8 X better) – Nov 2019
- Omega-3 reduces heart problems by ~5 percent – meta-analysis by Heart Association Oct 2019
- Cardiovascular Prevention with Omega-3 (finally using high doses) – Sept 2019
- Few people have enough EPA (an Omega-3) to reduce heart failures – July 2019
- Another Nail in the Coffin for Fish Oil Supplements (nope) – JAMA April 2018
- Omega-3 provides many cardiovascular benefits – April 2018
- Omega-3 helps the heart, AHA class II recommendation, more than 1 gm may be needed – March 2018
- 3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT March 2018
- Perhaps the Omega-3 optimal level is 10 percent, not 8 – Feb 2018
- Omega-3 Cardiovascular meta-analysis has at least 5 major problems – Jan 2018
- Benefits of Omega-3 beyond heart health - LEF Feb 2018
- Higher Omega-3 index (4 to 8 percent) associated with 30 percent less risk of coronary disease (10 studies) July 2017
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis May 2016
- For every Omega-3 dollar there is a 84 dollar savings in Cardiovascular costs - Foster and Sullivan April 2016
- High dose Omega-3 probably reduces heart problems – American Heart Association – March 2017
- Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
- Omega-3 – need more than 1 gram for a short time to reduce Cardiovascular Disease – Nov 2016
- Omega-3 is vital for health, mail-in test is low cost and accurate
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- Atrial fibrillation sometimes treated by Omega-3 – meta-analysis Sept 2015
- Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety – Nov 2014
- Omega-7 - in addition to Omega-3
- Omega-3 reduces Coronary Heart Disease - infographic June 2014
- Cardiovascular diseases – conflicting data on benefits of Omega-3 and vitamin D – Feb 2014
- Cardiovascular system benefits from both Omega-3 and vitamin D – Dec 2012
- Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues
- Omega-3 does not help heart patients – meta-analysis Sept 2012
Items in both categories Cardiovascular and Vitamin K-2 are listed here:
- Vitamin K, cardiovascular health, and stroke - many studies
- Bone loss results in blood vessel plaque if low Vitamin K2, less bone loss if high K2– April 2021
- Cardiovascular Disease prevented by Vitamin K2-4 when enough is used – RCT review Sept 2020
- Calcium Supplementation is OK provided you also take Vitamin K – Feb 2019
- Vitamin K reduces calcification (reported yet again) – Feb 2019
- Vitamin K (across all dose sizes and types) decrease Vascular Stiffness – meta-analysis - Dec 2018
- Vitamin D and Vitamin K together fight CVD Part 1- Pizzorno
- Vitamin K, Cardiovascular and interactions with Vitamin D and Vitamin A – Pizzorno July 2018
- Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
- Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
- Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT July 2017
- Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K – Aug 2017
- Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
- Cardiovascular death: 9 percent due to hypertension or air pollution, 7 percent: low Vitamin K2 or smoking – Oct 2016
- Decreased need for warfarin after Vitamin D levels optimized – RCT May 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- The health benefits of vitamin K – Oct 2015
- If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT May 2015
- Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Hypothesis: Vitamin K will reduce prostate blood vessel problems – Jan 2015
- Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013
- Cholesterol, Vitamins D3 and K2, heart disease, sulfates, LDL, – Masterjohn Interview Jan 2013
- Soft Bones, Hard Arteries, Vitamin D, Vitamin K2 and antibiotics – Sept 2012
- Low Vitamin D and Vitamin K: brittle bones and hardened arteries – LEF Sept 2010
Items in both categories Cardiovascular and Magnesium are listed here:
- More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased) - March 2021
- Nitric oxide increased by UVA, Vitamin D, Magnesium, etc,
- Atrial Fibrillation decreased by Vitamin D or Magnesium - many studies
- Signs of low Magnesium (heart problems in this case) – Jan 2018
- Ablation does not reduce atrial fibrillation (CABANA study) but Magnesium does – June 2018
- Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
- Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium – Aug 2017
- Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Atrial Fibrillation - remineralize your heart - Aug 2015
- Magnesium Suppresses Formation of Clogged Arteries - May 2014
- Off Topic: EDTA similar reduction in heart attack as Vitamin C, aspirin and Mg – RCT March 2013
- Death from Coronary Heart Disease related to low Magnesium intake – March 2013
- Magnesium prevents cardiovascular events – Meta-analysis March 2013
- Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
- Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues
See also web
- Arterial stiffness as a cause of cognitive decline and dementia: a systematic review and meta-analysis July 2012 5 of 6 studies found the association – Free PDF online
- Signs Of Cognitive Decline And Alzheimer’s Can Be Detected In Younger Adults 2018
Framingham Heart Study published in Stroke Journal - Association of Serum 25-hydroxy-vitamin D Concentration and Arterial Stiffness among Korean Adults in Single Center Feb 2017,  Download the PDF from VitaminDWiki
- Crosstalk between Vitamins A, B12, D, K, C, and E Status and Arterial Stiffness 2017
 Download the Nutrient PDF from VitaminDWiki - Effect of vitamin D supplementation on measures of arterial stiffness: a systematic review and meta-analysis of randomized controlled trials – May 2016
 Download the May 2016 PDF from VitaminDWiki
- Therapeutic modification of arterial stiffness: An update and comprehensive review Nov 2016
 Download the PDF from VitaminDWiki - Dietary potassium regulates vascular calcification and arterial stiffness Oct 2017
 Download the Potassium PDF from VitaminDWiki
“Reduced dietary potassium intake has been linked to the pathogenesis of a variety of human diseases, including atherosclerosis, diabetes, and chronic kidney disease”
“Concurrently with increased vascular calcification, we have found that PWV, an indicator of arterial stiffness, was increased in animals fed a low-potassium diet . . “ - 24 weeks of 350 mg Magnesium daily reduced arterial stiffness by 1 m/s May 2016
"Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial"
 Download the PDF from VitaminDWiki - Longitudinal observation of arterial stiffness in junior high school students. Dec 2017
"SBP, time for watching TV, and symptoms of depression and anxiety may contribute to arterial stiffness and have relation with obesity in junior high school students."
 Download the PDF from VitaminDWiki - Arterial Stiffness and Hypertension - Which Comes First? Sept 2017
Free PDF online
Arterial stiffness Wikipedia
"Measurement of aortic PWV provides some of the strongest evidence concerning the prognostic significance of large artery stiffening. Increased aortic PWV has been shown to predict cardiovascular, and in some cases all cause, mortality in individuals with end stage renal failure, hypertension,diabetes mellitus and in the general population" - Low vitamin D plus low Vitamin K ==> 6.8 X higher risk of Pulse Wave velocity higher than 9.3 meters/sec
Aug 2017