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Omega-3 – need more than 1 gram for a short time to reduce Cardiovascular Disease – Nov 2016

Omega-3 Fatty Acids and Cardiovascular Disease: Are There Benefits?

Current Treatment Options in Cardiovascular Medicine, November 2016, 18:69; DOI: 10.1007/s11936-016-0487-1
Kate J. BowenWilliam S. HarrisPenny M. Kris-Etherton

See also VitaminDWiki

Study seems to ignore the CVD benefits of Vitamin D, Vitamin K2, and Magnesium - some of which are in salmon and other fish

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Items in both categories Omega-3 Cardiovascular are listed here:

Pages listed in BOTH the categories Magnesium and Cardiovascular

 Download the PDF from VitaminDWiki

Opinion statement
Early secondary prevention trials of fish and omega-3 polyunsaturated fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) outcomes, including all-cause mortality and sudden cardiac death. These clinical findings, as well as observational and experimental data, demonstrated that omega-3 PUFAs reduced the risk of coronary outcomes and overall mortality and were the basis for recommendations made in the early 2000s to increase omega-3 PUFA intake. In the last 6 years, however, results from both primary and secondary prevention trials have generally failed to show a beneficial effect of omega-3 PUFA supplementation, bringing current recommendations into question.
Several possible reasons for these null findings have been proposed,

  • including short treatment periods,
  • relatively low doses of omega-3 PUFAs,
  • small sample sizes,
  • higher background omega-3 intakes, and the
  • concurrent use of modern pharmacotherapy for CVD prevention.

At least one of these caveats is being assessed in major clinical trials, with two omega-3 PUFA pharmacological agents being tested at doses of 4?g/day (instead of the more common <1 g/day). These null findings, however, do not necessarily mean that omega-3 PUFAs “are ineffective” in general, only that they were not effective in the context in which they were tested. Accordingly, higher intakes of omega-3 PUFAs, either from fatty fish or from supplements, if continued for decades (as the epidemiological data support) are likely to contribute towards lower risk for CVD. At this time, evidence supports the consumption of a healthy dietary pattern with at least two servings per week of fatty fish. Omega-3 PUFA supplementation is a reasonable alternative for those who do not consume fish, although fish is the preferred source of omega-3 PUFAs because it also provides additional nutrients, some of which are often under-consumed.

Attached files

ID Name Comment Uploaded Size Downloads
7269 Omega-3 etc salmon.jpg admin 31 Oct, 2016 18:10 67.29 Kb 440
7267 Omega-3 and CVD.pdf PDF 2016 admin 31 Oct, 2016 17:53 383.15 Kb 242
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