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Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues

For 40+ years Cardiovascular problems associated with low Magnesium

Magnesium and Vitamin D are synergistic, that is, increasing one helps the other.

Magnesium not Magnesium
Vitamin D Magnesium or Vitamin D
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Vitamin D only
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Not Vitamin D Magnesium only
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Items in both VitaminDWiki categories of Cardiovascular and Magnesium:

See also: VitaminDWiki and Web


Items in both categories Cardiovascular and Omega-3 are listed here:

Note: Increasing intake does not change Omega-3 index much if consume lots of Omega-6

Atrial Fibrillation: Vitamin D genes, etc

Afib 1.8 X more likely if poor Vitamin D Binding Protein
Genetically deprived vitamin D exposure predisposes to atrial fibrillation - 2017
Europace. 2017 Dec 1;19(suppl_4):iv25-iv31. doi: 10.1093/europace/eux312.
Chan YH1, Yiu KH1,2, Hai JJ1, Chan PH1, Lam TH3, Cowling BJ3, Sham PC4, Lau CP1, Lam KS2,5, Siu CW1,2, Tse HF1,2.
In VitaminDwiki as Atrial Fibrillation strongly associated with some vitamin D binding protein – Dec 2017
 Download the PDF from VitaminDWiki


AIMS: Low vitamin D level is associated with atrial fibrillation (AF) and may be implicated in its pathogenesis.

We studied single nucleotide polymorphisms (SNPs) of vitamin D mechanistic pathways and serum 25-hydroxyvitamin D [25(OH)D] levels in an age- and gender-matched case-control study (controls without AF: mean age 68.6 ± 8.7 years, female 25%; n = 1019; with AF: mean age 69.7 ± 9.5 years, female 30%; n = 156) recruited from a Chinese clinical cohort of patients with stable coronary artery disease. Twelve SNPs involved in the vitamin D mechanistic pathways were studied [biosynthetic: rs4646536, rs10877012, rs3829251, rs1790349; activation: rs2060793, rs1993116; vitamin D-binding protein (VBP)/group-specific component (GC): rs4588, rs7041, rs2282679, rs1155563; and vitamin D receptor: rs1544410, rs10735810]. A genetic risk score (GRS) (0-8) was constructed from SNPs associated with serum 25(OH)D as a proxy to lifelong vitamin D-deficient state.
All 4 SNPs involved in the VBP/GC were significantly associated with serum 25(OH)D (rs4588, P < 0.001; rs2282679, P < 0.001; rs7041, P = 0.011; rs1155563, P < 0.001; all other SNPs, P > 0.05). Vitamin D GRS (points 0-8) generated from these 4 SNPs was independently predictive of serum 25(OH)D [B = 0.54, 95% confidence interval (CI) 0.30-0.79; P < 0.001]. Genetically deprived vitamin D status as denoted by a low GRS (0-3) independently predicted an increased risk of AF, compared to a high GRS (4-8) (odds ratio = 1.848, 95% CI 1.217-2.805; P = 0.004).

CONCLUSION: Genetically deprived vitamin D exposure predisposes to increased AF among patients with coronary artery disease. Whether VBP/GC may alter the risk of AF via alternative mechanisms warrants further studies.

Vit D Binding Protein category listing has 174 items along with related searches

Note: Vitamin D Binding Protein problems are NOT noticed by Vitamin D blood test
in Visio for 2023

Cardiovascular category in VitaminDWiki starts with the following

499 items In Cardiovascular category

Cardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022

Cholesterol, Statins

This page was renamed Dec 2018. There have actually been 10589 visitors to this page since it was originally made

Created by admin. Last Modification: Monday July 26, 2021 09:51:41 GMT-0000 by admin. (Version 27)

Attached files

ID Name Comment Uploaded Size Downloads
11043 VDP atrial.jpg admin 14 Dec, 2018 15:55 17.79 Kb 964
11042 VDB top.jpg admin 14 Dec, 2018 15:55 17.63 Kb 892
11041 Chan-2017-Genetically-deprived-vitamin-d-expo.pdf admin 14 Dec, 2018 15:54 231.99 Kb 516
11040 Magnesium for Atrial Fibrillation, Myth or Magic.pdf admin 14 Dec, 2018 13:56 497.58 Kb 626
11039 Afib Meta.jpg admin 14 Dec, 2018 13:15 109.61 Kb 1118
11038 Treating arrhythmias with adjunctive magnesium.pdf admin 14 Dec, 2018 13:14 354.45 Kb 575