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Diabetes treated by vitamin D when levels exceeded 61 ng – Sept 2015

The Effect of Vitamin D Supplementation on Glycemic Control and Lipid Profile in Patients with Type 2 Diabetes Mellitus

Journal of the American College of Nutrition, online Sept 2015, DOI:10.1080/07315724.2015.1026427
Magda I. Mohamad MD ab*, Enas E. El-Sherbeny MD ab & Meram M. Bekhet Md ab
a Medical Biochemistry Department (M.I.M.), Endocrinology Department (M.M.B.), Faculty of Medicine, Ain Shams University, Cairo, EGYPT
b Public Health & Community Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, EGYPT (E.E.E.-S.)
Summary by VitaminDWiki

Total Cholesterol HDL-C LDL-C Triglycerides
<35 ng/ml 187 42 97 160
35–61ng/ml 15640 94 148
>61 ng/ml 147 48 79 132

Aim: The aim of this study was to evaluate the effect of vitamin D supplementation in patients with type 2 diabetes mellitus (T2DM) with regard to their glycemic control and lipid profile.

Methods: One hundred subjects with diabetes were recruited and given 4500 IU/day of vitamin D for 2 months. 25-Hydroxyvitamin D [25(OH)D], fasting blood glucose (FBG), glycosylated hemoglobin A1c (HbA1c), and lipid profile were measured pre- and postsupplementation.

Results: There was a significant increase in the mean value of 25(OH)D level after supplementation (baseline level 16 ± 5.3 ng/ml vs. after supplement level 49.2 ± 17.7 ng/ml, p < 0.05). Both FBG and HbA1c but not lipid profile were significantly decreased after supplementation. However, the univariate general linear model between 25(OH)D percentiles and lipid profile levels showed that subjects with diabetes with high 25(OH)D levels (>61 ng/ml) had significantly lower levels of total cholesterol and low-density lipoprotein cholesterol (LDL-C) in comparison to those in the low or middle percentiles. Furthermore, participants in a higher percentile had a significantly higher level of high-density lipoprotein cholesterol (HDL-C) than those in the middle percentile. Lipid profile levels were not affected by the supplement except for triglycerides (TG) levels in females, which were significantly decreased.

Conclusions: Vitamin D supplementation may be beneficial to subjects with diabetes because it improved glycemic control. Subjects with diabetes with high 25(OH)D levels (>61 ng/ml) had better lipid profiles.

PDF is available free at Sci-Hub   10.1080/07315724.2015.1026427

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Overview Diabetes and vitamin D contains the following summary

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 535 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

Number of articles in both categories of Diabetes and:
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  • Dark Skin 24;   Intervention 56;   Meta-analysis 38;   Obesity 35;  Pregnancy 44;   T1 (child) 39;  Omega-3 11;  Vitamin D Receptor 24;  Genetics 12;  Magnesium 27    Click here to see details

Some Diabetes studies

50 ng of Vitamin D fights Diabetes

T1 Diabetes


Diabetes, Metabolic Syndrome and Magnesium - many studies

Is 50 ng of vitamin D too high, just right, or not enough
Canadian foundation (Pure North) prevents chronic disease with 60 ng Vitamin D
Best Vitamin D- 40 to 52 ng, achieved with 4000 – 6000 IU daily – Heaney Oct 2014

Pages listed in BOTH the categories Diabetes and Intervention