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Prediabetes both prevented and treated by monthly Vitamin D, etc.


Diabetes and Diet

Prediabetes and progression to Diabetes

Prediabetes returns to normal if take Vitamin D

Vitamin D might also prevent becoming prediabetic

Zinc and Magnesium also reduce progression

Vitamin D treats Diabetes

Items in both categories Diabetes and non-daily intervention are listed here:

Progression to diabetes 5X less with Vitamin D – RCT Dec 2018

Does high-dose vitamin D supplementation impact insulin resistance and risk of development of diabetes in patients with pre-diabetes? A double-blind randomized clinical trial.
Diabetes Res Clin Pract. 2019 Feb;148:1-9. doi: 10.1016/j.diabres.2018.12.008
Niroomand M1, Fotouhi A2, Irannejad N3, Hosseinpanah F4.


Prediabetics got placebo or 50,000 IU weekly for 3 months (loading)
Then 50,000 IU monthly for 3 months (maintenace,,not enough)
At 6 months 10% of controls got diabetes, but only 2% of those getting Vitamin D (36 ng avg)

AIMS: The aim of this study is to evaluate the effect of high-dose vitamin D on insulin sensitivity and the risk of progression to diabetes.

In this double-blind, placebo-controlled randomized clinical trial adults with pre-diabetes and vitamin D deficiency were randomly assigned to either vitamin D3 or placebo. Fasting plasma glucose (FPG), 2-h oral glucose tolerance test plasma glucose (OGTT PG), Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), and the rate of progression of glucose tolerance was compared.

A total of 162 patients were randomized, from which 83 finished the 6-month follow-up (44 in intervention group and 39 in control group). In 6 months, serum 25-hydroxyvitamin D levels were significantly higher in the intervention group (36 ng/ml vs 16 ng/ml, P value < 0.001). There was no significant difference between FPG or 2H-OGTT PG in two groups. HOMA-IR score was significantly lower in the vitamin D group (2.6 vs. 3.1; P value = 0.04). The rate of progression toward diabetes was significantly lower in the intervention group (28% vs. 3%; P value = 0.002).

CONCLUSIONS: In patients with pre-diabetes and hypovitaminosis D, high dose vitamin D improves insulin sensitivity and decreases risk of progression toward diabetes.

Created by admin. Last Modification: Tuesday April 6, 2021 16:05:39 GMT-0000 by admin. (Version 17)

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11462 PreD.jpg admin 24 Feb, 2019 21:00 24.30 Kb 803