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Better lipid and diabetic profiles if higher level of vitamin D – March 2019

Effect of Vitamin D deficiency on Lipid Profile

American Journal of Laboratory Medicine, .Volume 4, Issue 1, January 2019, Pages: 11-18

  • Nabil Ahmad Bashir, Department of Physiology and Biochemistry and Department of Medical Laboratory Sciences, Faculty of Medicine, Balqa Applied University Medical School (Sabbatical) and Jordan University of Science and Technology, Irbid, Jordan
  • Adnan Ahmad Mohammad Bashir, Industrial Engineering Department, Abu Dhabi University and Hashemite University, Zarqa, Jordan
  • Hani Adnan Bashir, School of Medicine, Hashemite University, Zarqa, Jordan

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The purpose of this study is to investigate the effect of vitamin D deficiency on lipid parameters; cholesterol, triglycerides, low density lipoprotein (LDL), and high density lipoprotein (HDL). Serum level of vitamin D and the lipid parameters were determined in 127 subjects attending private community lab in eastern Amman province, using commercially available kits. Deficiency and insufficiency of vitamin D were 36.2%, 29.9%, respectively. Serum level of cholesterol, triglycerides, and LDL in deficient and insufficient vitamin D subjects were significantly increased, while HDL level was decreased, P-value <0.05. Serum levels of lipid profile and vitamin D in each of the control, insufficient , and deficient groups were all normally distributed due to the fact that P-value is greater than 0.05. Interval plot analysis and One-way ANOVA analysis revealed a significant effect of vitamin D insufficiency or deficiency on serum level of cholesterol, triglycerides, and LDL and increases the levels more than the double. Two samples T-test for every lipid parameter analysis related to subjects in the sufficient, insufficient and deficient vitamin D groups confirm our hypothesis on the effect of vitamin D deficiency on increasing the levels of cholesterol, triglycerides, and LDL and decreasing the level of HDL.

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