Treadmill exercise helps (Diabetics in this case) - Jan 2022

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Effect of Application of Treadmill Training on Metabolic Control and Vitamin D Level in Saudi Patients with Type 2 Diabetes Mellitus

Computational and Mathematical Methods in Medicine Volume 2022, Article ID 3059629, 7 pages https://doi.org/10.1155/2022/3059629

3 times per week

Ahmad El Askary ahmedelaskary3 at gmail.com, Alaa Shafie,1 Mazen Almehmadi Hatem H. Allam ,2
Lamiaa K. Elsayyad,2 Asmaa F. Hassan,3 Bader B. Althobaiti,4
Mohamed Mansour Khalifa,5,6 Tamer Saber,7 Aisha H. Alharthi,1 and Amal F. Gharib 1
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia
2Department of Physical Therapy, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia
3Department of Medical Physiology, College of Medicine, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia 4Department of Clinical Laboratories, King Abdulaziz Specialist Hospital in Taif, Ministry of Health, Taif, Saudi Arabia
5Department of Human Physiology, Faculty of Medicine, Cairo University, Egypt
6Department of Human Physiology, College of Medicine, King Saud University, Saudi Arabia
7Department of Internal Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Background. Diabetes mellitus type 2 and vitamin D deficiency are both prevalent in the Saudi Arabia. Vitamin D deficiency treatment with supplements carries a risk of intoxication. Aim. The present study is aimed at elucidating the effect of exercise on modulation of metabolic status and vitamin D level in patients with type 2 diabetes mellitus (T2DM).

Methods. A sum of 110 type 2 diabetic patients were voluntarily enrolled for the present investigation by dividing them into two separate groups (55 individuals for each group), the diabetic study group and diabetic control group. The diabetic study group was engaged in the training program using treadmill exercise. Laboratory parameters were monitored before and after the training program.

Results. There were significant elevation in the diabetic study group compared to diabetic control group regarding postexercise vitamin D level, high-density lipoprotein (HDL) (p value < 0.001, 0.045; respectively). In addition, triglycerides, low-density lipoprotein (LDL), glycosylated hemoglobin (HbA1C), and homeostatic model assessment-insulin resistance (HOMA-IR) were significantly decreased (p value < 0.001 for all mentioned parameters). Moreover, there were significant higher level in postexercise parameters as compared to preexercise level in the diabetic study group.

Conclusion. The exercise training program improved the metabolic control and vitamin D level after three months of intervention.
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VitaminDWiki pages with EXERCISE in title

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VitaminDWiki - Overview Diabetes and vitamin D contains

• Diabetes is 5X more frequent far from the equator
• Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
• Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
• Sedentary people get less sun / Vitamin D
• Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
• Elderly get 4X less vitamin D from the same amount of sun
      Elderly also spend less time outdoors and have more clothes on
• All items in category Diabetes and Vitamin D 564 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

• Appears that >2,000 IU will Prevent
• Appears that >4,000 IU will Treat , but not cure
• 90% less T2 Diabetes in the group having lots of Vitamin D
• Appears that Magnesium helps both Prevention and Treatment
• Many diabetics would be better treated if Gut-Friendly Vitamin D were used

Number of articles in both categories of Diabetes and:

• Dark Skin 25;   Intervention 57;   Meta-analysis 40;   Obesity 37;  Pregnancy 45;   T1 (child) 39;  Omega-3 12;  Vitamin D Receptor 25;  Genetics 13;  Magnesium 32    Click here to see details

Some Diabetes studies

• Take Vitamin D to prevent prediabetes from progressing into diabetes – American Diabetic Association – 2024
• Diabetes and Vitamin D meta-analyses - many studies 39+ as of Nov 2024
• 99.7% of people who got Diabetes had been regularly consuming food emulsifiers - May 2024
• Type 2 Diabetes treated by Vitamin D (often 50,000 IU weekly) – meta-analysis July 2023
• Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
• Incidence of Type-2 Diabetes increased 3X in 30 years (by the way, Vitamin D helps) – July 2022
• Vitamin d treats Type II Diabetes in many ways (14 article review) - Sept 2021
• T2 Diabetes 30 percent more likely if poor Vitamin D Receptor – meta-analysis of 47 studies – July 2021

50 ng of Vitamin D fights Diabetes

• Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020
• Diabetes 5X less likely if more than 50 ng of Vitamin D – April 2018

T1 Diabetes

• T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis Nov 2020
• Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies – Sept 2019
• Type 1 Diabetes prevention with Vitamin D and Omega-3 – Symposium April 2019

Pre-Diabetes

• 4X reduction in prediabetes progressing to T2D if more than 50 ng of vitamin D – RCT March 2023
• Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
• Prediabetes 1.5 X more likely to go away if take Vitamin D – meta-analysis July 2020

Diabetes, Metabolic Syndrome and Magnesium - many studies
Diabetic Epidemic

• Step back to 1994. Suppose an epidemic struck the United States, causing blindness, kidney failure, and leg amputations in steadily increasing numbers.
  Suppose that in less than a decade's time, the epidemic had victimized one out of every eight people
  That epidemic is real, and its name is diabetes, now the nation's sixth leading cause of death.
  Chart from the web (2018?)
  

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VitaminDWiki - Ways to improve health

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VitaminDWiki - Diabetes and Omega-3

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VitaminDWiki - Diabetes and Magnesium

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Suspect that Exercise + Vitamin D + Omega-3 + Magnesium would be great