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Low Vitamin D is associated with risk of Depression 5X, Stress 4.8 X, and Anxiety 3.9 X (Saudi Arabia college students) – July 2023


Impact of Vitamin D Deficiency on Mental Health in University Students: A Cross-Sectional Study

Healthcare (Basel) . 2023 Jul 23;11(14):2097. doi: 10.3390/healthcare11142097.
Mansour Almuqbil 1, Moneer E Almadani 2, Salem Ahmad Albraiki 3, Ali Musharraf Alamri 3, Ahmed Alshehri 4, Adel Alghamdi 5, Sultan Alshehri 6, Syed Mohammed Basheeruddin Asdaq 7

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Students pursuing a university education are vulnerable to psychological burdens such as depression, anxiety, and stress. The frequency of vitamin D deficiency, on the other hand, is extensively recognized worldwide, and vitamin D regulates various neurological pathways in the brain that control psychological function. Therefore, the goal of this cross-sectional study was to determine the relationship between vitamin D deficiency and psychological burden among university students in Riyadh, Saudi Arabia. During March-May 2021 in Riyadh, a cross-sectional comparative study survey was delivered to university students. The DASS-21 scale was used to determine the severity of the psychological burden. Both univariate and binomial regression analyses were conducted to analyze the level of significance and influence of several factors on the development of psychological burden. The data were analyzed with SPSS-IBM, and a p value of <0.05 was considered significant. Of the 480 students recruited for the study, 287 (59.79%) had a vitamin D deficiency. Significantly (p = 0.048), a high proportion of the vitamin D-deficient students attained a low or moderate GPA compared to the control cohort.
The prevalence of depression, anxiety, and stress among the vitamin D-deficient students was 60.35%, 6.31%, and 75.08%, respectively, which was significantly (p < 0.05) different from the control group.
The odds of developing

  • depression (OR = 4.96; CI 2.22-6.78; p < 0.001),
  • anxiety (OR = 3.87; CI 2.55-6.59; p < 0.001), and
  • stress (OR = 4.77; CI 3.21-9.33; p < 0.001)

were significantly higher in the vitamin D-deficient group. The research shows a strong association between psychological stress and vitamin D deficiency. To promote the mental health and psychological wellbeing of university students, it is critical to create awareness about the adequate consumption of vitamin D. Additionally, university students should be made aware of the likelihood of a loss in academic achievement owing to vitamin D deficiency, as well as the cascade effect of psychological burden.
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Intervention of Vitamin D for Depression


Meta-analyses of Vitamin D and Depression


VitaminDWiki – Depression contains

Some recent publications


14+ VitaminDWiki pages have ANXIETY in the title

This list is automatically updated

Items found: 16
Title Modified
New anxiety after age 50 predicts 2.1 X increased risk of Parkinson’s – July 2024 06 Jul, 2024
International Adolescent Anxiety and suicide rates - GBD April 2024 07 Apr, 2024
Half as much anxiety and sleep problems if get lots of vitamin D from food (excluded getting D from supplements) – Feb 2024 23 Feb, 2024
Anxiety, Vitamin D, Omega-3 - many studies 23 Feb, 2024
Low Vitamin D is associated with risk of Depression 5X, Stress 4.8 X, and Anxiety 3.9 X (Saudi Arabia college students) – July 2023 29 Jul, 2023
Parkinson’s – Vitamin D, bone density, insomnia, falls, poor sleep, anxiety – March 2019 10 May, 2023
Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022 22 Dec, 2022
Depression and Anxiety treatment with Vitamin D - probable molecular pathways - June 2022 21 Dec, 2022
Coronary Artery Disease Chest Pain, Anxiety, and Fatigue associated with low vitamin D – Oct 2022 07 Oct, 2022
Anxiety, depression, and suicide have recently surged (Note: Vitamin D, Omega-3, and Magnesium help) – May 2022 29 May, 2022
General Anxiety Disorder treated by weekly Vitamin D (50,000 IU -Omega-3, Mg also help) – Sept 2019 09 Dec, 2019
Omega-3 reduces Depression. Anxiety, Stress, PTSD, etc. – Aug 2018 02 Sep, 2019
Happy Nurses Project gave Omega-3 for 3 months – reduced depression, insomnia, anxiety, etc for a year – RCT July 2018 10 Nov, 2018
Anxiety severity reduced if more than 2 grams of Omega-3 – meta-analysis Sept 2018 19 Sep, 2018
Why is teen anxiety increasing so much (no mention of Magnesium, Vitamin D nor Omega-3) – Oct 2017 11 Oct, 2017
Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety – Nov 2014 11 Feb, 2015


VitaminDWiki – Mental stress, physical stress associations with low vitamin D - many studies

Attached files

ID Name Comment Uploaded Size Downloads
19872 Experience when less than 20 ng.jpg admin 29 Jul, 2023 60.47 Kb 184
19871 Mental Health Saudi_CompressPdf.pdf admin 29 Jul, 2023 297.35 Kb 63