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  1. 40 percent less likely to get adequate vitamin D response if have certain genes – Jan 2013
  2. Activation (methylation) of CYP2R1 and CYP24A1 predict response to dose of vitamin D – Oct 2013
  3. CYP24A1 enzyme and Vitamin D
  4. CYP2R1 (vitamin D 25-hydroxylase ) semiactivates vitamin D in many places in the body
  5. CYP2R1 gene probably responsible for low vitamin D response – RCT April 2014
  6. Difference in Fok gene reduced response to vitamin D by 35 percent – Nov 2012
  7. Epigenetics - PDFs and links, with and without Vitamin D
  8. Epigenetics meets endocrinology – 2011
  9. GC and CYP2R1 genes associated with higher summer vitamin D levels – Jan 2013
  10. Gene activation by high dose vitamin D - both quick and long term - April 2015
  11. Genetic influence on Vitamin D is small compared to environmental influence – July 2011
  12. Genome-wide association study of circulating vitamin D levels -May 2010
  13. Genome-wide view on the physiology of vitamin D – April 2014
  14. Gene problem discovered by taking Vitamin D, sibling had same gene problem – Dec 2019
  15. Genes affect vitamin D processing in many places - 2010
  16. Genes and different vitamin D related substances in the skin – Jan 2013
  17. Health problems can persist through many generations – Epigenetics and Vitamin D
  18. Hypothesis: Stem cells need vitamin D too – Jan 2012
  19. More than 5X increase in activation of scores of genes for women with Vitamin D (20,000 IU weekly) RCT Oct 2017
  20. More genes changed with higher doses of Vitamin D (suggest future gene studies) - RCT Dec 2019
  21. Migration to Northern Latitudes enabled by mutation of gene: DHCR7 resulting in more vitamin D – July 2013
  22. Mice lacking CYP2R1 enzyme activate about half of much vitamin D – Sept 2013
  23. Metabolites and genes may predict responses to Calcium and Vitamin D – Jan 2011
  24. Low frequency hearing loss (Otosclerosis) associated with vitamin D genes– April 2013
  25. Novel vitamin D gene regulation – CYP21A2 – May 2012
  26. People 2 cm taller had different Calcium and Vitamin D genotypes – Mar 2012
  27. Neurofibromatosis – 1 in 3500 have it, associated with low vitamin D
  28. Poor CYP2R1 gene reduces blood response to Vitamin D supplementation – Aug 2019
  29. Response to Vitamin D varied by 12 ng due to gene variants (CYP2R1) – Aug 2019
  30. The genetics of vitamin D – Oct 2018
  31. Telomeres (which extend life) appear to be extended by Vitamin D - March 2015
  32. Trying to understand the effect of genetics vitamin D levels in the blood – Jan 2013
  33. Twins reduction in vitamin D in the winter or summer - Nov 2010
  34. Vitamin D - Health panacea or false prophet (Klotho gene) – Jan 2013
  35. Vitamin D affects at least 3,023 DNA locations – July 2018
  36. 2 Genes make AMD 6X more likely if low vitamin D - Aug 2015
  37. 2,776 vitamin D receptor binding sites - April 2014
  38. 291 genes improved expression by 2000 IU of vitamin D – RCT March 2013
  39. 3X higher risk of oral cancer if CYP27B1 and CYP24A1 genes were different – May 2012
  40. 5.8 X more likely to die in 15 year followup if low vitamin D and poor methylation – July 2018
  41. 5839 genes changed during pregnancy (many genes were related to Vitamin D) – Oct 2016
  42. 8 genes associated with both Alzheimer’s and lowish Vitamin D – May 2019
  43. 98 pcnt of genes that Vitamin D activates to reduce MS are also activated by Interferon -May 2013
  44. Afib increase by 3X for the 1 in 16 people having poor genes (example of health problem) – Aug 2018
  45. Asthma related to vitamin D by 4 plausible genes – Nov 2013
  46. Asthma strongly associated with modification in vitamin D genes
  47. Breast cancer and Vitamin D receptors, CP27B1, and CYP24A1 – Sept 2010
  48. Breast Cancer rate reduced 72 percent by vitamin D gene polymorphism CYP24A1 – Nov 2014
  49. Calcium problems associated with CYP24A1 (a Vitamin D gene) – Oct 2017
  50. Colorectal cancer – need more vitamin D if you have certain genes – Aug 2013

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