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Prediabetes corrected in 3 months by 1,000 IU of vitamin D as pill or in yogurt – RCT Jan 2018

Fortified yogurt with vitamin D as a cost-effective food to prevent diabetes: A randomized double-blind clinical trial

Journal of Functional Foods, Vol 42, March 2018, Pages 137-145, https://doi.org/10.1016/j.jff.2018.01.001


Highlights

  • Anthropometric indices in the fortified-yogurt and oral-supplement groups decreased significantly.
  • Oral glucose tolerance tests (OGTT) decreased significantly in only the fortified-yogurt group.
  • The mean fasting serum insulin and the insulin-resistance index in the fortified-yogurt and oral-supplement groups decreased significantly.
  • These findings showed that vitamin D-fortified yogurt is the low-cost approach to decrease vitamin D deficiency in Iranian people.

Vitamin D has a role in both insulin secretion and insulin sensitivity, and thus could be important in the pathogenesis of diabetes. The aim of this study was to compare the effect of yogurt fortified with vitamin D and oral vitamin D supplement on glycemic and anthropometric indices in pre-diabetic individuals.
This study was conducted on 90 subjects with pre-diabetes in three groups:

  • those given fortified yogurt with vitamin D,
  • those given plain yogurt and
  • those given oral vitamin D supplements.

The study variables were evaluated at the beginning and end of the intervention period.
Results from the participants’ oral glucose tolerance tests (OGTT) decreased significantly in only the fortified-yogurt group.
   [Note: The PDF did not show the difference to be statistically significant]
The mean fasting serum insulin and the insulin-resistance index (HOMA-IR) in the fortified-yogurt (p < .01) and oral-supplement (p < .03, p < .04) groups decreased significantly. Waist-to-hip ratio (WHR) and percentage of body fat (PBF) decreased significantly in the fortified-yogurt (p < .02, p < .006) and oral-supplement (p = .015, p < .001) groups. These findings show that yogurt fortified with vitamin D improves glycemic and anthropometric indices in pre-diabetic individuals.


Clipped from PDF – obtained via Sci-Hub.tw

  • “To ensure that the subjects would consume the yogurt, they were given 10 packs for self-consumption and 10 packs for other family members to consume”
  • “To fortify the yogurt with vitamin D we used vitamin D powder (dry vitamin D3 100 SD/S, containing 100,000 IU vitamin D3 per gram, suitable for fortification of water-based foods, product code: 5010950.304; DSM Nutritional Products Ltd., Basel, Switzerland”
       Note: This is similar form to the Vitamin D by Bio-Tech Pharmacal
Created by admin. Last Modification: Monday January 29, 2018 14:32:21 UTC by admin. (Version 3)
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