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Covid-19, T cells, and Vitamin D


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VitaminDWiki - Immunity and Virus


COVID and T-Cell Studies from the web

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 June 29

COVID-19 progression is potentially driven by T cell immunopathogenesis May 19, 2020

  • "Our data further reveal that increased rather than decreased SARS-CoV-2 specific T cell immunity is associated with adverse outcome in COVID-19

Single-Cell Analysis Reveals Macrophage-Driven T Cell Dysfunction in Severe COVID-19 Patients May 26

  • "Together, our results suggest that severe SARS-CoV-2 infection causes immune dysregulation by inducing M2 polarization and subsequent T cell exhaustion."

Impaired T cell functions along with elevated activated Tregs at the early stage of asymptomatic SARS-CoV-2 infection

  • "Interpretation The T cell activation in the asymptomatic SARS-CoV-2 infection experienced a significant suppression and presented impairment of Th1/Th17 and CD8+ T cell functions"

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19) peer reviewed May 1
COVID-19 patients can rapidly generate virus-attacking T cells, shows study June 27

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases - Jan 26  PDF
Vitamin D deficiency correlates with a reduced number of natural killer cells in intensive care unit (ICU) and non-ICU patients with COVID-19 pneumonia Dec 8  PDF


COVID-19 treated by Vitamin D - studies, reports, videos

As of June 14, 2022, the VitaminDWiki page had:  34 trials 11 trial results,   36 meta-analyses and reviews,   69 observations,   38 recommendations,   55 associations,  89 speculations,  58 videos, 45 Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   26 risk factors are ALL associated with low Vit D,   Recent Virus pages   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   COVID Clinical Trials (06/22) using Vit D: 114,   Vit D & Zinc: 26,   Calcidiol: 26


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