Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials.
Endocr Pract. 2009 Jul-Aug;15(5):438-49. doi: 10.4158/EP09101.ORR.
Yamshchikov AV1, Desai NS, Blumberg HM, Ziegler TR, Tangpricha V.
1Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30030, USA. AYAMSHC at emory.edu
- Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015
- How to significantly reduce your risk of contracting the Zika virus
- All items in category Virus
Immunity category starts with
192 items in Immunity category
see alsoVirus category listing has
145 items along with related searches
Overview Influenza and vitamin D
Search for treg OR "t-cell" in VitaminDWiki 610 items as of March 2017
Search VitaminDWiki for INFECTION 6,940 items as of Aug 2019
Search VitaminDWik for INFECTION in title 50 items as of Aug 2019
Search VitaminDWik for BACTERIA in title 25 items as of Aug 2019
Vitamin D Every Day to Keep the Infection Away 2015 file
shows increasing publications on vitamin D and Infection
OBJECTIVE: To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in settings of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence reviewed.
METHODS: We conducted a systematic review of randomized controlled clinical trials that studied vitamin D for treatment or prevention of infectious diseases in humans. Studies from 1948 through 2009 were identified through search terms in PubMed and Ovid MEDLINE.
RESULTS: Thirteen published controlled trials were identified by our search criteria. Ten trials were placebo controlled, and 9 of the 10 were conducted in a rigorous double-blind design. The selected clinical trials demonstrated substantial heterogeneity in baseline patient demographics, sample size, and vitamin D intervention strategies. Serious adverse events attributable to vitamin D supplementation were rare across all studies. On the basis of studies reviewed to date, the strongest evidence supports further research into adjunctive vitamin D therapy for
- viral upper respiratory tract illnesses.
In the selected studies, certain aspects of study design are highlighted to help guide future clinical research in the field.
CONCLUSION: More rigorously designed clinical trials are needed for further evaluation of the relationship between vitamin D status and the immune response to infection as well as for delineation of necessary changes in clinical practice and medical care of patients with vitamin D deficiency in infectious disease settings.
Download the PDF from VitaminDWiki
3355 visitors, last modified 22 Jul, 2016, URL: