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COVID-19 activates and Vitamin D de-activates 12 cytokines (mini-review)– May 2021

Vitamin D regulation of the immune system and its implications for COVID-19: A mini review

SAGE Open Medicine Volume 9: 1-8 © DOI: 10.1177/20503121211014073
Linda Bui, Zahra Zhu1, Stephanie Hawkins1, Alonso Cortez-Resendiz and Alfredo Bellon1,2,3
this is a subset of table in the PDF


Vitamin D titles containing "cytokine"

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COVID-19 treated by Vitamin D - studies, reports, videos

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The novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is at the origin of the current pandemic, predominantly manifests with severe respiratory symptoms and a heightened immune response. One characteristic of SARS-CoV-2 is its capacity to induce cytokine storm leading to acute respiratory distress syndrome. Consequently, agents with the ability to regulate the immune response, such as vitamin D, could become tools either for the prevention or the attenuation of the most severe consequences of the coronavirus disease 2019 (COVID-19). Vitamin D has shown antimicrobial as well as anti-inflammatory properties. While SARS-CoV-2 promotes the release of proinflammatory cytokines, vitamin D attenuates the release of at least some of these same molecules. Inflammatory cytokines have been associated with the clinical phenomena of COVID-19 and in particular with its most dangerous complications.

Therefore, the goals of this article are as follows:

  • first, present the numerous roles vitamin D plays in modulating the immune response;
  • second, gather data currently available on COVID-19 clinical presentation and its relation to cytokines and similar molecules;
  • third, expose what it is known about how coronaviruses elicit an inflammatory reaction; and
  • fourth, discuss the potential contribution of vitamin D in reducing the risk and severity of COVID-19.

Created by admin. Last Modification: Saturday May 29, 2021 15:52:07 GMT-0000 by admin. (Version 7)

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15660 Cytokines increase and decrease.jpg admin 29 May, 2021 12:56 21.86 Kb 349
15659 Vit D and COVID-19 minireview.pdf PDF 2021 admin 29 May, 2021 12:56 200.39 Kb 286