Serum 25(oH)D level in patients with CoVID-19
DOI: 10.22625/2072-6732-2020-12-3-21-27
T.L. Karonova 1 karonova at mail.ru, А.Т. Andreeva 1 arabicaa at gmail.com, М.А. Vashukova 2 mavashukova at yahoo.com
1 National Medical Research Centre named after V.A. Almazov, Saint-Petersburg, Russia
2 Clinical Infectious Hospital named after S.P. Botkin, Saint-Petersburg, Russia
COVID-19 treated by Vitamin D - studies, reports, videos
- As of March 31, 2024, the VitaminDWiki COVID page had: trial results, meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
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Virus - Vitamin D Intervention in VitaminDWiki
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- Single 600,000 IU dose of nanoemulsion Vitamin D is safe and effective to fight COVID, even if delay until enter ICU – RCT May 2024
- COVID death rate in hospital halved if take any amount of vitamin D for any length of time – meta-analysis May 2024
- COVID and Vitamin D: 2X more likely to die if low, 2X more likely to survive if supplement – umbrella meta-analysis April 2024
- COVID fought by Vitamin D: 2.3X less likely to die of COVID if supplemented, 1.9 X less likely to become infected – meta-analysis March 2024
- 5 X less COVID infection of health care workers who took lots of vitamin D – meta-analysis Feb 2024
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- calcifediol rct
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Virus - Vitamin D Loading Dose in VitaminDWiki
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English Abstract
Recently, vitamin D deficiency is considered as a risk factor for the incidence and severity of new coronavirus infection. The aim of this work was to evaluate the vitamin D level of patients with COVID-19 hospitalized with communityacquired pneumonia and compare the value of 25(OH)D in blood serum with the clinical manifestations of the disease.
Results. Included are 80 patients aged 18 to 94 years (mean age 53,2 ± 15,7 years), 43 (53,8%) men; with severe
course – in 25 (31,3%) patients (12 males), and moderate – in 55 people (68,7%) (31 males). Half of the severely
ill patients were obese, and among the deceased patients, the number of obese people was 61,5%, which was significantly higher than the discharged ones – 14,9% (p<0,001). Diabetes mellitus and cardiovascular diseases occurred with the same frequency, regardless of the severity of the disease.
Analysis of the outcomes of coronavirus infection in these patients showed mortality in 52,0% of cases in severe patients.
Serum 25(OH)D level ranged from 3,0 to 88,8 ng / ml (16,7 ± 12,7 ng / ml). It was found that in patients with severe course, the level of 25(OH)D blood was significantly lower (11.9 ± 6.4 ng / ml) and vitamin D deficiency was more common than in patients with moderate to severe course of the disease (18,5 ± 14,0 ng / ml, p = 0,027). The same pattern was revealed in patients with a fatal outcome, where the level of 25(OH)D was 10,8 ± 6,1 ng / ml, compared with this indicator in patients discharged from the hospital (17,8 ± 13,4 ng / ml) (p = 0,02).
Conclusions. Vitamin D deficiency and obesity have been found to increase the risk of severe course and death of coronavirus infection.