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Multiple Sclerosis depression reduced by 10,000 IU of vitamin D – Jan 2019

Effect of vitamin D replacement on depression in multiple sclerosis patients.

Mult Scler Relat Disord. 2019 Jan 23;29:111-117. doi: 10.1016/j.msard.2019.01.029.
Kotb MA1, Kamal AM2, Aldossary NM3, Bedewi MA3.


Note: Getting a lot more Vitamin D actually cures MS

Intervention of Vitamin D for Depression

Meta-analyses of Vitamin D and Depression

Depression category listing has 245 items along with related searches

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MS Depression - baseline
MS Depression after 8 months (note the change of scales)
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. Depression is common among MS patients. In patients without MS, lower vitamin D levels were associated with higher depression scores and severity. Supplementation of vitamin D was associated with significant improvement of depressive symptoms.

OBJECTIVE: to evaluate the relation between vitamin D levels and depression scores, and the effect of vitamin D replacement on the depressive symptoms in patients with MS.

The study included 35 patients with relapsing remitting multiple sclerosis. Neurological, psychiatric, and radiological evaluations were done. Participants received 10,000 IU of cholecalciferol daily for 12 months.

Vitamin D level was low at baseline. Depressive symptoms were high at baseline and improved with vitamin D replacement although, Expanded Disability Status Scale (EDSS) score was not improving. Vitamin D levels correlated negatively with depressive symptoms at baseline and follow up periods.

Lower vitamin D levels are associated with higher depressive scores, and vitamin D replacement could improve depressive symptoms in patients with relapsing remitting multiple sclerosis.

Created by admin. Last Modification: Sunday February 3, 2019 14:11:33 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
11326 MS depression.jpg admin 03 Feb, 2019 14:04 40.23 Kb 466
11325 Depression 8 months.jpg admin 03 Feb, 2019 14:03 30.75 Kb 419
11324 Depression baseline.jpg admin 03 Feb, 2019 14:03 31.34 Kb 406
11323 Depression MS.pdf PDF 2019 admin 03 Feb, 2019 14:03 800.85 Kb 535