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Multiple Sclerosis depression reduced by 10,000 IU of vitamin D – Jan 2019

Effect of vitamin D replacement on depression in multiple sclerosis patients.

Mult Scler Relat Disord. 2019 Jan 23;29:111-117. doi: 10.1016/j.msard.2019.01.029.
Kotb MA1, Kamal AM2, Aldossary NM3, Bedewi MA3.

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Note: Getting a lot more Vitamin D actually cures MS

Intervention of Vitamin D for Depression

Meta-analyses of Vitamin D and Depression

Depression category listing has 202 items along with related searches

 Download the PDF from Sci-Hub via VitaminDWiki
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MS Depression - baseline
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MS Depression after 8 months (note the change of scales)
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BACKGROUND:
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. Depression is common among MS patients. In patients without MS, lower vitamin D levels were associated with higher depression scores and severity. Supplementation of vitamin D was associated with significant improvement of depressive symptoms.

OBJECTIVE: to evaluate the relation between vitamin D levels and depression scores, and the effect of vitamin D replacement on the depressive symptoms in patients with MS.

METHODS:
The study included 35 patients with relapsing remitting multiple sclerosis. Neurological, psychiatric, and radiological evaluations were done. Participants received 10,000 IU of cholecalciferol daily for 12 months.

RESULTS:
Vitamin D level was low at baseline. Depressive symptoms were high at baseline and improved with vitamin D replacement although, Expanded Disability Status Scale (EDSS) score was not improving. Vitamin D levels correlated negatively with depressive symptoms at baseline and follow up periods.

CONCLUSION:
Lower vitamin D levels are associated with higher depressive scores, and vitamin D replacement could improve depressive symptoms in patients with relapsing remitting multiple sclerosis.

Created by admin. Last Modification: Sunday February 3, 2019 14:11:33 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
11326 MS depression.jpg admin 03 Feb, 2019 14:04 40.23 Kb 117
11325 Depression 8 months.jpg admin 03 Feb, 2019 14:03 30.75 Kb 97
11324 Depression baseline.jpg admin 03 Feb, 2019 14:03 31.34 Kb 93
11323 Depression MS.pdf PDF 2019 admin 03 Feb, 2019 14:03 800.85 Kb 54
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