Journal of Stroke and Cerebrovascular Diseases, online 26 Oct 2017, https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.030
Yerim Kim, MD, MSc, Jong Seok Bae, MD, PhD, Hong-Ki Song, MD, PhD, Ju-Hun Lee, MD, PhD, leejuhun at hallym.or.kr
- Twice as many fatal strokes among whites who were low on vitamin D – Jan 2012
- Stroke 74% less likely if high vitamin D (7,295 women 20-50 years old) – July 2017
- Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K – Aug 2017
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- Vitamin K2 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
- Ischemic Stroke risk reduced by 2.5 if have good level of vitamin D – meta-analysis Feb 2018
- Stroke volume half as large if had good level of vitamin D (mice) – Feb 2018
- Ischaemic Stroke has less impact in animals supplemented with Omega-3 – Jan 2018
- Migraines double the risk of strokes (both are associated with low vitamin D) – Jan 2018
- Strokes 3 X worse if low vitamin D – Jan 2018
- Large vessel Ischemic Stroke 13 X more likely if low vitamin D – Nov 2017
Although intracranial arterial calcifications (IACs) are encountered in approximately 85% of patients with acute ischemic stroke (IS), the significance of IAC in plaque instability is still controversial. Because most tissues including brain tissue have vitamin D receptors, vitamin D deficiency might play multiple roles in variable sites. Here, we report a novel presentation of IS with IAC including anterior cerebral artery involvement due to vitamin D deficiency.
In conclusion, although the role of IAC in cerebral infarction is still controversial, we suggest that insufficient vitamin D should be examined and treated appropriately in all patients with IS. We believe that this article provides important implications for the treatment of vitamin D deficiency in patients with IS.