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On the job sleepiness 2.2X more likely if low vitamin D – Feb 2020

Impacts of Serum Vitamin D Levels on Sleep and Daytime Sleepiness According to Working Conditions

J Clin Sleep Med, 2020 Feb 21, DOI: 10.5664/jcsm.8390
Hyuk Joo Lee 1, Hayun Choi 2, In-Young Yoon 1 3

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Little change in Vitamin D level with season for day-workers

Study objectives: Low serum vitamin D levels are known to be associated with working conditions and poor sleep, but precedent studies on this issue were limited by the absence of objective sleep measurements or clear distinction between daytime and night shift work. Hence, we aimed to examine serum vitamin D levels and sleep in daytime and night-shift workers using actigraphy.

Methods: A total of 412 night-shift and 432 daytime workers at Seoul National University Bundang Hospital were recruited. All participants completed questionnaires regarding demographic and clinical characteristics. They underwent blood tests for serum vitamin D levels. Objective sleep data were obtained from 150 night-shift workers and 203 daytime workers using actigraphy.

Results: There was no significant difference in serum vitamin D levels between night-shift and daytime workers after controlling for possible confounders.
In daytime workers, vitamin D deficiency was closely related to

  • shorter duration of total sleep time [odds ratio (OR): 3.07, 95% confidence interval (CI): 1.51 - 6.26, P = 0.002] and
  • higher risk of excessive daytime sleepiness (OR: 2.20, 95% CI: 1.30 - 3.74, P = 0.003).

Deficient vitamin D was also associated with

  • life quality impairment regarding psychological health (OR: 1.83, 95% CI: 1.07 - 3.29, P = 0.028) and
  • social relationship (OR: 1.78, 95% CI: 1.10 - 2.88, P = 0.020).

However, in night-shift workers, no significant association was observed between serum vitamin D level and sleep parameters, depressive/anxiety symptoms, or quality of life.

Conclusions: The modest adverse impact of poor vitamin D status on sleep could be attenuated by substantial shift work-related sleep disturbances in night-shift workers. Further studies might be needed to clarify the beneficial effect of vitamin D supplementation for improving sleep and daytime sleepiness in workers with various working conditions.


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