25-hydroxyvitamin D status, light exposure and sleep quality in UK dwelling South Asian and Caucasian postmenopausal women.
J Steroid Biochem Mol Biol. 2019 Jan 30. pii: S0960-0760(18)30385-6. doi: 10.1016/j.jsbmb.2019.01.020.
Darling AL1, Hart KH2, Arber S3, Berry JL4, Morgan PL5, Middleton BA5, Lanham-New S2, Skene DJ6.
Note: the Dark-skinned women also got substantially less bright light during the day
Items in both categories Sleep and Skin-dark are listed here:
- Vitality recaptured with Vitamin D (stories of Swedish immigrant women in this case) – Dec 2019
- Sleep fragmentation 2X worse in UK senior women having dark skins – Jan 2019
- African-Americans with poor sleep have lower levels of vitamin D – Aug 2015
- Sleep disorder and nonspecific pain implies low vitamin D, especially if dark skin – March 2013
Sleep often improved with Vitamin D and B Vitamins
- Sleep, Vitamin D, B Vitamins, jaw, etc. Dr. Gominak transcript - 2016
- Sleep may be regulated by Vitamin D via two pathways – Nov 2018
- Poor sleep 1.5 X more likely if less than 20 ng of Vitamin D – meta-analysis Oct 2018
- Sleeps disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017
- The Better Sleep Vitamin (Vitamin D) – nice 3 dollar book Feb 2015
- Comparing High-dose vitamin D therapies
- Two of the high-dose therapies specifically deal with sleep
Sleep category starts with
A few items in SLEEP category
- Sleep greatly improved by 50,000 IU of vitamin D once every two weeks – RCT Sept 2018
- Sleeps disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017
- Sleep, Dr. Gominak and Vitamin D - several studies
- Restless Legs Syndrome dramatically reduced by vitamin D, etc
- On the job sleepiness 2.2X more likely if low vitamin D – Feb 2020
- Poor sleep 1.5 X more likely if less than 20 ng of Vitamin D – Feb 2019
- The Better Sleep Vitamin (Vitamin D) – nice 3 dollar book Feb 2015
- The worse the sleep apnea, the lower the vitamin D levels – meta-analysis 2017, 2020
- Vitamin D for better sleep video - Dec 2021
- 5X increase in sleep problems in a decade in US Veterans
- Sleep Apnea and Vitamin D - many studies
- Melatonin and Vitamin D - many studies does much more than improve sleep
 Download the PDF from Sci-Hub via VitaminDWiki
There is a lack of research into 25-hydroxyvitamin D (25(OH)D) status, light exposure and sleep patterns in South Asian populations. In addition, results of research studies are conflicting as to whether there is an association between 25(OH)D status and sleep quality. We investigated 25(OH)D status, self-reported and actigraphic sleep quality in n = 35 UK dwelling postmenopausal women (n = 13 South Asians, n = 22 Caucasians), who kept daily sleep diaries and wore wrist-worn actiwatch (AWL-L) devices for 14 days. A subset of n = 27 women (n = 11 South Asian and n = 16 Caucasian) also wore a neck-worn AWL-L device to measure their light exposure. For 25(OH)D concentration, South Asians had a median ± IQR of 43.8 ± 28.2 nmol/L, which was significantly lower than Caucasians (68.7 ± 37.4 nmol/L)(P = 0.001).
Similarly, there was a higher sleep fragmentation in the South Asians (mean ± SD 36.9 ± 8.9) compared with the Caucasians (24.7 ± 7.1)(P = 0.002). Non-parametric circadian rhythm analysis of rest/activity patterns showed a higher night-time activity (L5) (22.6 ± 14.0 vs. 10.5 ± 4.4; P = 0.0008) and lower relative amplitude (0.85 ± 0.07 vs. 0.94 ± 0.02; P < 0.0001) in the South Asian compared with the Caucasian women. More South Asians (50%) met the criteria for sleep disorders (PSQI score >5) than did Caucasians (27%) (P = 0.001, Fishers Exact Test). However, there was no association between 25(OH)D concentration and any sleep parameter measured (P > 0.05) in either ethnic group. South Asians spent significantly less time in illuminance levels over 200 lux (P = 0.009) than did Caucasians. Overall, our results show that postmenopausal South Asian women have lower 25(OH)D concentration than Caucasian women. They also have higher sleep fragmentation, as well as a lower light exposure across the day. This may have detrimental implications for their general health and further research into sleep quality and light exposure in the South Asian ethnic group is warranted.
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