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How Vitamin D can fight cerebrovascular diseases (stroke, TIA, aneurysm) – March 2022


Vitamin D as therapeutic modulator in cerebrovascular diseases: a mechanistic perspectives

Critical Reviews in Food Science and Nutrition, 14 Mar 2022,
https://doi.org/10.1080/10408398.2022.2050349 behind paywall
Vivek Rihal,Heena Khan,Amarjot Kaur &Thakur Gurjeet Singh

Vitamin D deficiency has been linked to several major chronic diseases, such as cardiovascular and neurodegenerative diseases, diabetes, and cancer, linked to oxidative stress, inflammation, and aging. Vitamin D deficiency appears to be particularly harmful to the cardiovascular system, as it can cause endothelial dysfunctioning and vascular abnormalities through the modulation of various downstream mechanisms. As a result, new research indicates that therapeutic approaches targeting vitamin D inadequacies or its significant downstream effects, such as impaired autophagy, abnormal pro-inflammatory and pro-oxidant reactions, may delay the onset and severity of major cerebrovascular disorders such as stroke and neurologic malformations. Vitamin D modulates the various molecular pathways, i.e., Nitric Oxide, PI3K-Akt Pathway, cAMP pathway, NF-kB Pathway, Sirtuin 1, Nrf2, FOXO, in cerebrovascular disorder. The current review shows evidence for vitamin D’s mitigating or slowing the progression of these cerebrovascular disorders, which are significant causes of disability and death worldwide.


VitaminDWiki - Stroke category

108 items in stroke category - see also Overview Stroke and vitamin D,
Overview Hypertension and Vitamin D  Overview Cardiovascular and vitamin D

Stroke more likely if low Vitamin D

Post-Stroke worse if low Vitamin D

Post-Stroke better if add Vitamin D

Post-Stroke better if Vitamin D actually gets to cells


VitaminDWiki - Hypertension category

152 items in the category HYPERTENSION

see also
Overview Overview Hypertension and Vitamin D
Overview Cardiovascular and vitamin D
Overview Stroke and vitamin D
Incidence of 22 health problems related to vitamin D have doubled in a decade
Some interesting Hypertension studies


VitaminDWiki pages with NITRIC in title

This list is automatically updated

Items found: 10




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