Water-soluble form of vitamins are needed for some health problems

Which health problems result in having poor adsorption of fat-soluble vitamins - asked Perplexity AI Sept 2024

Several health problems can result in poor absorption of fat-soluble vitamins like vitamin A:

1. Fat malabsorption syndromes: Disorders that impair the intestine's ability to absorb fats can reduce the absorption of fat-soluble vitamins A, D, E and K. These disorders include
   chronic diarrhea,
   Crohn's disease,
   cystic fibrosis,
   certain pancreatic disorders, and
   blockage of the bile ducts.
2. Liver disorders: Liver diseases can interfere with the processing, metabolism or storage of fat-soluble vitamins like vitamin A. This can lead to deficiencies even if dietary intake is adequate.
3. Inflammatory bowel disease (IBD): Conditions like
   Crohn's disease and
   ulcerative colitis cause inflammation in the intestines that can impair fat and fat-soluble vitamin absorption, increasing the risk of deficiencies.
4. Short bowel syndrome: If large sections of the small intestine are surgically removed or non-functional, it can significantly reduce the surface area available to absorb fats and fat-soluble vitamins, leading to deficiencies.
5. Celiac disease: The chronic immune reaction to gluten in celiac disease damages the small intestine lining, impairing its ability to absorb nutrients including fats and fat-soluble vitamins.
6. Certain medications: Some drugs like mineral oil laxatives, bile acid sequestrants, and the fat substitute olestra can impair absorption of fat-soluble vitamins if used long-term.
7. Alcoholism: Alcohol abuse can damage the pancreas and intestines, impairing fat digestion and absorption of fat-soluble vitamins. Alcoholic liver disease also interferes with vitamin metabolism and storage.

So in summary, any condition that impairs fat digestion/absorption in the intestines or interferes with vitamin metabolism in the liver can potentially lead to deficiencies in fat-soluble vitamins like vitamin A. Monitoring vitamin levels is important in patients with these conditions.
8 references in Perplexity AI

Also TB

Which health problems are associated with poor guts - asked Perplexity AI Sept 2024

Based on the provided search results, several health problems are associated with poor gut health:
Gastrointestinal Disorders

• Inflammatory bowel disease (IBD)
• Irritable bowel syndrome (IBS)
• Digestive symptoms like gas, bloating, constipation, diarrhea, and heartburn

Metabolic Disorders

• Obesity
• Type 2 diabetes

Cardiovascular Diseases
Mental Health Disorders

• Anxiety
• Depression
• Mood changes

Sleep Disturbances and Fatigue
Autoimmune Diseases

• Thyroid issues
• Rheumatoid arthritis
• Multiple sclerosis
• Type 1 diabetes

Skin Conditions

• Acne
• Eczema
• Psoriasis

Neurological Conditions

• Autism
• Migraines

Other Conditions

• Cancer
• Food intolerances
• Unintentional weight changes
• Frequent infectious illnesses

In summary, poor gut health is linked to a wide range of chronic diseases affecting the gastrointestinal system, metabolism, cardiovascular system, brain, immune system, skin, and more. Maintaining a healthy gut microbiome appears to be important for overall physical and mental well-being.
9 references in Perplexity AI

What about Parkinson's? - asked Perplexity AI

Gastrointestinal Symptoms in PD

• Constipation is one of the most common GI symptoms, affecting 60-80% of PD patients. It can occur years before motor symptoms.
• Other frequent GI issues include bloating, nausea, vomiting, difficulty swallowing (dysphagia), and irritable bowel syndrome (IBS).
• GI dysfunction in PD involves the esophagus, stomach, and intestines due to effects on the autonomic and enteric nervous systems

Constipation adds: multiple sclerosis, and stroke

VitaminDWiki – Overview Gut and vitamin D contains gut-friendly vitamin D information