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3rd most common dementia perhaps might also be associated with low vitamin D: Lewy Body - Oct 2012

Pure speculation – based on no data, just some associations

Alzheimer’s and Parkinson’s Disease are both associated

Lew Body dementia is associated with muscle spasms – low Magnesium/Vitamin D?


Dementia with Lewy bodies: the principles of diagnostics, treatment, and management.
Medicina (Kaunas). 2012;48(1):1-8.
Macijauskien? J, Lesauskait? V.
Department of Geriatrics, Medical Academy, Lithuanian University of Health Sciences, A. Mickevi?iaus 9, 44307 Kaunas, Lithuania. jurate.macijauskiene at lsmuni.lt

Dementia with Lewy bodies was first recognized as a separate entity about 30 years ago. The prevalence varies from 0% to 5% in the general population, and this disease accounts for 0% to 30.5% of all dementia cases.

Dementia with Lewy bodies is considered the second most common cause of degenerative dementia after Alzheimer's disease.

The disease is characterized by alpha-synuclein immunoreactive protein deposits in both neurons and glial cells. The protein deposits are especially prominent in dopaminergic neurons, where they can be detected using conventional histological stains, such as hematoxylin and eosin, and are commonly referred to as Lewy bodies.

The diagnosis of dementia with Lewy bodies is based on the presence of dementia as well as 2 of the following 3 core diagnostic features:

  • 1) fluctuating cognition,
  • 2) visual hallucinations, and
  • 3) movement disorder.

Diagnostic tests include laboratory data, structural and functional imaging, and electroencephalography. Differential diagnosis of dementia with Lewy bodies focuses on other later life dementia syndromes, other parkinsonian diseases (Parkinson's disease, progressive supranuclear palsy, corticobasal degeneration), and primary psychiatric illnesses. There is type 1b evidence to support treatment with cholinesterase inhibitors. Glutamatergic and dopaminergic therapies are used as well. Standard neuroleptics are contraindicated, and atypical agents should be used cautiously. Nonpharmacologic measures - therapeutic environment, psychological and social support, physical activity, behavioral management strategies, caregivers' education and support, and different services - could be suggested.

PMID: 22481369
PDF is attached at the bottom of this page

See also VitaminDWiki

See also web

  • A Form of Dementia That Is Often Misdiagnosed New York Times – Sept 2012
    About 1.3 million Americans
    Frequently misdiagnosed as Alzheimer’s or Parkinson’s disease
    At a minimum, cognitive decline that doesn’t take the classic form of memory loss is a cue
    Lewy body dementia seems to progress more rapidly than Alzheimer’s; most patients don’t live as long with it
  • Wikipedia
  • PubMed Lewy and Dementia in title 1166 items as of Sept 2012

Attached files

ID Name Comment Uploaded Size Downloads
1630 Lewy body dementia.pdf PDF admin 01 Oct, 2012 01:20 199.77 Kb 588
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