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Lewy Body Dementia (Robin Williams) and low Vitamin D

See also VitaminDWiki

Robin's Wish - Movie Sept 2020

‘Robin’s Wish’ erases the sad clown trope around Robin Williams’s death
Includes link to the video trailer
"“He never got bitter,” Norwood continues. “He never got angry. Robin Williams wasn’t the guy who was going to go burn down the neighborhood the last night he was alive because he felt like things were unfair. He went and asked for a hug from one of his close friends. He said goodnight to his wife. And he realized that there just wasn’t much left on the earth for him. He was about two weeks from going into an inpatient program that he likely never would have come out of. And that’s just not how the guy wanted to live.”

Lewy Body dementia is associated with muscle spasms – low Magnesium/Vitamin D? - 2012

Dementia with Lewy bodies: the principles of diagnostics, treatment, and management.
Medicina (Kaunas). 2012;48(1):1-8.
Macijauskien? J, Lesauskait? V.
Department of Geriatrics, Medical Academy, Lithuanian University of Health Sciences, A. Mickevi?iaus 9, 44307 Kaunas, Lithuania. jurate.macijauskiene at lsmuni.lt

Dementia with Lewy bodies was first recognized as a separate entity about 30 years ago. The prevalence varies from 0% to 5% in the general population, and this disease accounts for 0% to 30.5% of all dementia cases.

Dementia with Lewy bodies is considered the second most common cause of degenerative dementia after Alzheimer's disease.

The disease is characterized by alpha-synuclein immunoreactive protein deposits in both neurons and glial cells. The protein deposits are especially prominent in dopaminergic neurons, where they can be detected using conventional histological stains, such as hematoxylin and eosin, and are commonly referred to as Lewy bodies.

The diagnosis of dementia with Lewy bodies is based on the presence of dementia as well as 2 of the following 3 core diagnostic features:

  • 1) fluctuating cognition,
  • 2) visual hallucinations, and
  • 3) movement disorder.

Diagnostic tests include laboratory data, structural and functional imaging, and electroencephalography. Differential diagnosis of dementia with Lewy bodies focuses on other later life dementia syndromes, other parkinsonian diseases (Parkinson's disease, progressive supranuclear palsy, corticobasal degeneration), and primary psychiatric illnesses. There is type 1b evidence to support treatment with cholinesterase inhibitors. Glutamatergic and dopaminergic therapies are used as well. Standard neuroleptics are contraindicated, and atypical agents should be used cautiously. Nonpharmacologic measures - therapeutic environment, psychological and social support, physical activity, behavioral management strategies, caregivers' education and support, and different services - could be suggested.

PMID: 22481369
PDF is attached at the bottom of this page

58+ VitaminDWiki pages with DEMENTIA in title

This list is automatically updated

Items found: 58
Title Modified
Dementia prevented by Omega-3, Vitamin D, etc. book and video May 2024 30 May, 2024
Vitamin D deficiency increases risk of Dementia by 1.4 X and Alzheimer’s by 1.5 X – Meta-analysis March 2024 11 Mar, 2024
Early-Onset Dementia 1.6X more likely if low Vitamin D - Dec 2023 12 Jan, 2024
Dementia (vascular) risk increase 60% if take Folate with other B vitamins - Dec 2023 16 Dec, 2023
The End of Alzheimer's and Dementia if adjust Vitamin D, B-12, Iron, Omega-3, etc. 19 Aug, 2023
Seniors taking vitamin D were 40% less likely to get dementia - Jan 2023 28 Jul, 2023
Poor bone health is a ‘robust’ dementia risk factor (both associated with Low vitamin D) - March 2023 31 Mar, 2023
Dementia 2.6 X more likely if very low Vitamin D – March 2023 19 Mar, 2023
The Role of Vitamin D in Reducing Risk of Alzheimer’s and Dementia - transcript Dr. Grant March 2023 12 Mar, 2023
Dementia again associated with low Vitamin D – 15th study in 10 years – Jan 2023 03 Mar, 2023
Neurodegenerative diseases (AD, PD, MS, Dementia, etc.) fought by Vitamin D (in rodents) – Jan 2023 24 Feb, 2023
How Vitamin D fights neurodegeneration (Multiple Sclerosis, Alzheimer’s, Dementia, etc) – Jan 2023 12 Jan, 2023
Alzheimer’s Dementia 2.3X more likely in elderly if low vitamin D – Dec 2022 06 Jan, 2023
Dementia is associated with low vitamin D - many studies 02 Jan, 2023
Dementia 1.35 X more-likely if poor diet – Oct 2022 13 Oct, 2022
Doggie dementia 6.5X more likely if not get exercise (probably low vitamin D) - Aug 2022 27 Aug, 2022
Dementia 2X more likely after ICU (suspect low Vitamin D) - Aug 2022 02 Aug, 2022
Calcitriol (activated Vitamin D) increases dementia (however, regular D decreases it) – June 2022 13 Jul, 2022
Vitamin Supplementation and Dementia - Review May 2022 11 May, 2022
Lewy Body Dementia (Robin Williams) and low Vitamin D 11 May, 2022
Dementia 10X lower in a group who are outdoors a lot and eat unprocessed foods - March 2022 07 Apr, 2022
Mild cognitive impairment is 3X more likely to become dementia in one year if low vitamin D – March 2022 07 Apr, 2022
Dementia 1.7X higher risk if diabetic and low vitamin D - Jan 2022 14 Feb, 2022
Dementia 4.1 X high risk in those with low Vitamin D, Omega-3, etc.2 decades before (behind paywall) – Nov 2021 22 Nov, 2021
Dementia reduced 26 percent after pollution was reduced a decade earlier (probably higher Vitamin D) – Aug 2021 19 Aug, 2021
Cognitive Impairment and Dementia often associated with low Vitamin D – April 2020 08 Jan, 2021
The Evidence is strong: Air pollution seems to cause dementia (perhaps low Vitamin D) – May 2019 09 May, 2019
Vitamin or Mineral Supplements Don’t Prevent Dementia (only one Vitamin D trial, it used 400 IU) – Feb 2019 04 Feb, 2019
Treating herpes reduced incidence of senile dementia by 10 X (HSV1 reduces VDR by 8X) – 2018 17 Jan, 2019
Why dementia gets more severe in the winter – Jan 2019 14 Jan, 2019
Vitamin D and neurological diseases such as stroke, Vascular Dementia, PD, MS - July 2018 07 Dec, 2018
Osteoporosis in men increased their risk of Dementia by 1.3 (60,000 Germans) – July 2018 21 Aug, 2018
Dementia – clinical trial using 4,000 IU of Vitamin D– 2023 02 Aug, 2018
Dementia risk increased 2.4 X following TBI, even if had not lost consciousness – May 2018 12 May, 2018
Dementia less likely with increased levels of Magnesium etc. 18 Apr, 2018
5 Traumatic brain injuries resulted in 2.8 X increased risk of dementia – April 2018 11 Apr, 2018
Off Topic: Dementia risk reduced 90 percent if woman had been highly fit 40 years before 18 Mar, 2018
Risk of Dementia and Alzheimer's reduced by higher levels of Vitamin D – meta-analysis Feb 2018 16 Feb, 2018
Should you have a dementia advanced directive - Jan 2018 19 Jan, 2018
Dementia risk reduced 29 percent by just 10 hours of computer brain plasticity training – RCT Dec 2017 08 Dec, 2017
Vitamin D and Multiple Sclerosis, Alzheimer's, Parkinson's ,Dementia, and ALS - review Nov 2017 23 Nov, 2017
Heart Attack increased risk of vascular dementia by 1.35 X (both associated with low vitamin D) Oct 2017 15 Nov, 2017
Dementia risk factor is increased by 1.5 if low vitamin D – meta-analysis Jan 2017 15 Jan, 2017
Dementia 19X more likely if low vitamin D – Jan 2012 27 Oct, 2016
The "Surprising Link" Between Vitamin D Deficiency and Dementia (nope) - Oct 2015 04 Oct, 2016
The "Surprising Link" Between Vitamin D Deficiency and Dementia (not a surprise) - Oct 2015 04 Oct, 2016
Dementia risk significantly increased if have 4 chronic diseases – all associated with low vitamin D – Sept 2015 11 Dec, 2015
Vascular dementia (after strokes) 32X more likely in Hypertensives with low vitamin D – Oct 2015 01 Nov, 2015
Dementia surprisingly associated with low vitamin D (should not a surprise) – Aug 2014 03 Oct, 2015
Dementia 13X more likely in elderly with low vitamin D – May 2014 04 Sep, 2015
Dementia risk increases with latitude (less vitamin D) - Feb 2015 20 Feb, 2015
Chance of Dementia increased 3 percent for every 1 ng less of vitamin D – Feb 2015 04 Feb, 2015
The Single Vitamin That's a Double Whammy Against Both Depression and Dementia (Mercola) – Aug 2014 21 Aug, 2014
More depression associated with more dementia in seniors (vitamin D not mentioned) – July 2014 31 Jul, 2014
Age-adjusted dementia may be declining – NEJM Dec 2013 01 Jan, 2014
Dementia risk increases 60 percent if have low vitamin D – Nov 2012 16 Dec, 2013
Dementia associated with low vitamin D in two thirds of studies – systematic review May 2013 01 Aug, 2013
Vitamin D might might reduce dementia – Mar 2011 23 Jun, 2012

Type of Dementia - by Perplexity AI June 2024 (Note Lewy body dementia has day to day variability)

The type of dementia can significantly influence the daily variability of symptoms. Here's how different types of dementia affect symptom fluctuations:

  1. Lewy body dementia: This type of dementia is known for its pronounced day-to-day variability in symptoms. Patients with Lewy body dementia often experience fluctuating levels of attention and alertness that can vary significantly from one day to the next. This variability is a hallmark feature of the condition.
    (perhaps President Biden has Lewy body dementia)
  2. Alzheimer's disease: While Alzheimer's symptoms generally progress gradually, there can still be some variability in the early stages. However, the fluctuations are typically less dramatic than those seen in Lewy body dementia.
  3. Vascular dementia: This type of dementia, caused by problems with blood flow to the brain, may show a more stepwise progression of symptoms. While day-to-day variability might be less pronounced, symptoms can worsen suddenly after events like small strokes.
  4. Frontotemporal dementia: This less common form of dementia tends to affect behavior and language more than memory in its early stages. The variability of symptoms may depend on the specific areas of the brain affected.
  5. Mixed dementia: When a person has more than one type of dementia, the variability in symptoms can be more complex, potentially combining characteristics of the different types involved.

It's important to note that regardless of the type of dementia, there tends to be some variability in a person's presentation from day to day, with periods of lucidity alternating with periods of confusion. However, the extent and nature of this variability can differ based on the specific type of dementia.As dementia progresses to later stages, symptoms generally become more severe and consistent across all types, with less day-to-day variability. Sudden, dramatic changes in condition over a short period might indicate a separate health issue rather than typical dementia progression.Understanding these differences in symptom variability can help caregivers and healthcare providers better manage care and recognize when changes might warrant further medical attention.

VitaminDwiki - Cognitive category contains

Very brief summary of Cognitive decline
Treatment : Vitamin D intervention slows or stops progression
Prevention : Many observational studies - perhaps Vitamin D prevents
Omega-3 both prevents and treats cognition
Wonder the benefits if both Vitamin D AND Omega-3 were to be used
Dementia page - 50 items

379 items in Cognition category

see also Overview Alzheimer's-Cognition and Vitamin D
Overview Parkinson's and Vitamin D

Studies in both categories of Cognition and:
Cardiovascular (7 studies), Genetics (9 studies), Vitamin D Receptor (16 studies), Omega-3 (50 studies), Intervention (19 studies), Meta-analyses (22 studies), Depression (23 studies), Parkinson's (22 studies)
Click here for details

Poor cognition 26 percent more likely if low Vitamin D (29 studies) – meta-analysis July 2017
Every schizophrenia measure was improved when vitamin D levels were normalized – June 2021
Cognitive Impairment and Dementia often associated with low Vitamin D – April 2020
IQ levels around the world are falling (perhaps lower Vitamin D, Iodine, or Omega-3)
Search VitaminDWiki for "WHITE MATTER" 325 items as of March 2023

Types of evidence that Vitamin D helps brain problems - 2014

See also web

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Created by admin. Last Modification: Sunday June 30, 2024 22:08:08 GMT-0000 by admin. (Version 31)
Lewy Body Dementia (Robin Williams) and low Vitamin D        
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Attached files

ID Name Comment Uploaded Size Downloads
14236 LBD venn.jpg admin 01 Sep, 2020 56.72 Kb 1104
14235 LBD progression.jpg admin 01 Sep, 2020 53.10 Kb 1016
1630 Lewy body dementia.pdf admin 01 Oct, 2012 199.77 Kb 1032