Loading...

Toggle Health Problems and D

Dementia risk increases 60 percent if have low vitamin D – Nov 2012

Association between serum 25(OH) vitamin D and the risk of cognitive decline in older women.

J Gerontol A Biol Sci Med Sci. 2012 Oct;67(10):1092-8. Epub 2012 Mar 27.
Slinin Y, Paudel M, Taylor BC, Ishani A, Rossom R, Yaffe K, Blackwell T, Lui LY, Hochberg M, Ensrud KE; Study of Osteoporotic Fractures Research Group.
Center for Chronic Disease Outcomes Research, VA Medical Center, Minneapolis, Minnesota, USA. slini001 at umn.edu

BACKGROUND: Results of prospective studies examining the association between 25 hydroxyvitamin D (25[OH]D) levels and cognitive decline have been inconsistent. We tested the hypothesis that lower 25(OH)D levels are associated with a greater likelihood of cognitive impairment and risk of cognitive decline.

METHODS: The study is a cross-sectional and longitudinal analysis of a prospective cohort of 6,257 community-dwelling elderly women followed for 4 years. Global cognitive function was measured by the Modified Mini-Mental State Examination and executive function was measured by Trail Making Test Part B (Trails B ).

Cognitive impairment at baseline was defined as a score >1.5 SD below the sample mean; cognitive decline was defined as decline from baseline to follow-up >1 SD from mean change in score.

RESULTS: Women with very low vitamin D levels had an increased odds of global cognitive impairment at baseline: odds ratio (95% confidence interval), 1.60 (1.05-2.42) for women with 25(OH)D <10 ng/mL (25 nmol/L) compared with those with 25(OH)D levels ?30 ng/mL (75 nmol/L).

Compared with women with baseline 25(OH)D level ?30 ng/mL (75 nmol/L), women with lower levels had an increased risk of global cognitive decline: odds ratio (95% confidence interval), 1.58(1.12-2.22) for women with levels <10 ng/mL (25 nmol/L), and 1.31 (1.04-1.64) for those with levels 10-19.9 ng/mL (25-49 nmol/L). Levels of 25(OH)D were not associated with executive cognitive function.

CONCLUSIONS: Low 25(OH)D levels among older women were associated with a higher odds of global cognitive impairment and a higher risk of global cognitive decline.

PMID: 22454371

See also VitaminDWiki

Dementia risk increases 60 percent if have low vitamin D – Nov 2012

4180 visitors, last modified 16 Dec, 2013,

Printer Friendly Follow this page for updates

Links to this page
- Adults with intellectual disabilities under psychiatric care have low levels of vitamin D – Sept 2014

This page is in the following categories (# of items in each category)

Cognitive 389 Shut-in 38

Edit

“One pill every two weeks fights diabetes, cancers, heart failure, and 21 other diseases.”

Click for details

Health Problems and D

15,500+ pages in VitaminDWiki
Topic (# in topic)

Acne (20+ studies)

Attention Deficit Hyperactivity Disorder/ADHD (52+)

Alcohol (29+)

Allergy (120+) Overview

Amyotrophic Lateral Sclerosis/ALS (30+)

Alzheimer's (81+) Overview

Ankylosing Spondylitis (20+)

Antibiotics/Probiotics (92+) Overview

Asthma (145+) Overview

Atopic Dermatitis Overview (18+)

Autism (163) Overview

Vit. D Receptor (14+)

Transgender (19+)

Autoimmune (204+)

Systemic Sclerosis (10+)

Back Pain (44+)

Lumbar Degeneration (14+)

Bipolar Disorder (16+)

Bone - Health (313+)

BMD, Bone loss (55+)

Breathing (453+)

Hay Fever (20+)

Pneumonia (50+)

Respiratory (82+)

Burns/Wounds (30+)

Cancer (293+) Overview

After diagnosis (113+)

Bladder (28+)

Bone (8+)

Breast (259+) Overview

Child (16+)

Colon (145+) Overview

Endometrial (5+)

Gastric (9+)

Leukemia (19+)

Liver (17+)

Lung (55+) Overview

Lymphoma (26+)

Mg and Cancer (13+)

Melanoma (43+)

Multiple Myeloma (10+)

Metastatic (17+)

Other (66+)

Ovarian (26+)

Palliative Care (10+)

Pancreatic (58+)

Prostate (103+) Overview

Skin (121+) Overview

Survive (37+)

Thyroid (7+)

{DIV}

Cardiovascular (529+) Overview

Atherosclerosis (56+)

Atrial Fibrillation (20+)

Heart Failure (47+)

HRV (10+)

Omega-3 (38+)

Statins (80+)

Carpal Tunnel Syndrome (12+)

Cerebral Palsy (6+)

Cholesterol (52+) Overview

Chronic Fatigue (7) Overview

Cognitive (389+) Overview

Anesthesia ==> Cog

Brain (103+)

Delirium (9+)

Dementia (50+)

Mental Illness (300+)

Mental Stress (10+)

Colds/flu Overview

Concussions (25+)

Chronic obstructive pulmonary disease/COPD (17+)

COVID-19 (1300+)

Cystic Fibrosis (52+)

Dental (116+)

Fluoridation (16)

Depression (268+)

Anxiety ( 11+)

Omega-3 (29)

SAD (9)

Diabetes (551+) Overview

Hemodialysis (41+)

Magnesium (27+)

Meta-analyses (39+)

Metabolic Syndrome + Mg

Neuropathy (15+)

Prediabetes (30+)

Red Meat (4+)

Retinopathy (8+)

Type 1 Diabetes (46+)

Vitamin D Receptor (23+)

Zinc (5+)

Diseases general (93+)

Ear (17+)

Otitis Media (10+)

Endometriosis (8+)

Falls/Fractures (258+) Overview

Fatigue, Chronic Overview

Fertility/Sperm (142+)

Erectile Dysfunction (12+)

In Vitro Fert. (18+)

Testosterone (14+)

Fibromyalgia Overview

Fractures Overview

Ankle (16+)

Bone & Stress Fractures

Bone Mineral Density (28+)

Children (16+)

Hip Fractures (68+)

Vertigo (22+)

Genetics (343+)

CYP24A1 (31+)

CYP24R1 (25+)

CYP27B1 (62+)

Epigenetics (18+)

Telomere (12+)

Vit D Binding (177+)

Vit D Receptor (517+)

Cancer in VDR (79+)

Gestational Diabetes (34+)

Gout (13+)

Gut (207+) Overview

Bariatric (15+)

Celiac (7+)

Clostridium difficile (9+)

Crohn's (38+)

IBD (28+)

IBS (18+)

Ulcerative Colitis (12+)

Hair (20+)

Alopecia Areata (8+)

Health - general (109+)

Human Immunodeficiency Virus/HIV (45+) Overview

Hives (10+)

Hypertension (165+) Overview

Pregnancy (41+)

Hyperparathyroid Overview

Immunity (273+)

Inflammation (175+)

CRP (19+)

Infection (141+)

Influenza Overview

Kidney (230+) Overview

Chronic Kidney (63+)

Dialysis (39+)

Kidney Stones (29+) Overview

Leprosy (16+)

Liver (102+) Overview

Hepatitis-B (12+)

Hepatitis-C (13+)

NAFLD (27+)

Lyme Disease (9+)

Lupus (78+)

Mental Illness (20+)

Mental Stress (5+)

Metabolic Syndrome (106+) Overview

Mortality (296+)

Multiple Sclerosis (412+) Overview

Genetics and Receptor (32+)

Virus (16+)

Muscle (113+)

Handgrip (12+)

Sarcopenia (30+)

Muscular Dystrophy (9+)

Myopia (17+)

Obesity (442+)Overview

Child & Youth (60+)

Vitamin D Receptor (16+)

Virus and Obesity (25+)

Weight Loss (31+)

Osteoarthritis (61+) Overview

Knee (26+)

Osteoporosis (220+) Overview

BMD (26+)

Pain - chronic (167+) Overview

Magnesium (13+)

Pancreatitis (20+)

Parkinson's (117+) Overview

Pneumonia (22+)

Pollution (31+)

Pregnancy (920+) Overview

Breastfed (38+)

Caesarean (15+)

Depression (21+)

Dark Skin (30+)

Gestational Diabetes (41+)

In Vitro Fert. (18+)

Iodine (21+)

Low Birth Weight (23+)

Magnesium (30+)

Miscarriage (31+)

Multiple Sclerosis (13+)

Omega-3 before and during (49+)

PCOS (15+)

Preeclampsia (55+)

Preterm (125+)

Preterm - Omega-3 (13+)

Stillbirth (8+)

Prostate - BPH (16+)

Psoriasis (72+)

Respiratory Tract Infection/RTI (8+)

Restless Legs Syndrome (15+)

Rheumatoid Arthritis (117+) Overview

Juvenile RA (9+)

Rickets (127+) Overview

Sarcopenia (28+)

Schizophrenia Overview

Sepsis (201+)

Sickle Cell (20+) Overview

Skin (122+) Overview

Aging

Atopic Dermatitis(27+)

Hives

Vitiligo (8+)

Sleep (101+)

Sleep Apnea(12+)

Smoking (83+)

Spinal Cord (21+)

Spinal Surgery (13+)

Statins (40+)

Stroke (131+) Overview

Cognitive Impairment (15+)

Depression (9+)

Ischemic (21+)

Thyroid/Parath. (82+) Overview

PTH (34+)

Trauma/Surgery (352+)

Bariatric surgery (12+)

Bone surgery (23+)

ICU & Loading Dose (69+)

Need Vit D (69+)

Ortho. & Hip (69+)

Sepsis (41+)

Transplant (31+)

Traumatic Brain Injury (24+)

Tuberculosis (125+) Overview

Urinary Tract Infection (15+)

Virus (1400+)

All studies

Bird Flu

Cardiovascular (19+)

Cancers after VAX (17+)

Child - years after VAX (11+)

Cognitive (10+)

Dengue (27+)

Epstein-Barr Virus (20+)

Excess Deaths (23+)

Hepatitis (29+)

Herpes or Shingles (13+)

Ivermectin (35+)

Long-COVID (72+)

Magnesium (60+)

Masks (11+)

Meta-analyses (40+)

Omega-3 (14+)

Pfizer (20+)

RSV (12+)

Ultraviolet light (16+)

Vaccination (198+)

Vitamin D (650+)

Vitamin D Receptor (31+)

Vitamin K

Zinc (32+)

Vision (112+)

Cataracts (13+)

Diabetic Retinopathy (8+)

Dry Eye (12+)

Glaucoma (8+)

Macular Degeneration (20+)

Myopia (20+)

Uveitis (10+)

People and Low Vitamin D

Infant/Child (854+)

Allergy (36+)

Cancer (13+)

Cerebral Palsy (15+)

Down Syndrome (5+)

Fracture, low energy (10+)

Growing Pains (10+)

Pneumonia (25+)

Preemie (25+)

Puberty early if low D (9+)

Respiratory (21+)

RSV (25+)

Tonsils (9+)

Vaccination (10+)

Virus (42+)

Military (27+)

Veterans (17+)

Prisoners (14+)

Seniors (430+) Overview

Aging (38+)

Essential Tremor (4+)

Frailty (20+)

Longevity (47+)

Nursing Homes (19+)

Sarcopenia (25+)

Urinary incontinence (15+)

Vertigo (22+)

Skin - Dark (460+) Overview

Pregnancies (30+)

Sports (277+) Overview

Exercise (68+)

Muscle (138+)

Traumatic Brain Inj. (24+)

Women (196+) Overview

Endometriosis (25+)

Incontinence (16+)

Menopause (17+)

PCOS

Premenstrual Syndrome (20+)

Uterine Fibroid (13+)

Yeast Infection

Youth (175+)

Early Puberty (15+)

Locations

World (14+)

Aust NZ (68+)

Africa (28+)

Europe (233+)

India (65+)

Iceland (40+)

Middle East (154+)

Orient (77+)

Russia (12+)

Scotland (20+)

Far from Equator (124+)

Click here to search the site
A list includes 288+ pages having many studies
# of studies as of Dec 11, 2024