In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars

Considering IVF? Here’s How Much It Costs In Canada Sept 2019

“Infertility affects one in six heterosexual couples in Canada”
One round of IVF costs $10,000 to $20,000
“IVF gets expensive because the most any province will cover is one round... and on average, it takes 2.7 rounds of IVF in order to get pregnant.

How an Israeli Startup Is Using AI to Help People Make Babies Jan 2021

• " Insurance rarely covers IVF, and the costs run anywhere from $12,000 to $25,000 per cycle (a cycle takes about a month and includes stimulating a woman’s ovaries to produce eggs, extracting the eggs, inseminating them outside the body, and implanting an embryo)."
• "They used 8,789 time-lapse videos of developing embryos to train an algorithm that predicts the likelihood of successful embryo implantation."
• "...the company reports that using its algorithm resulted in a 12 percent increase in positive predictive value (identifying embryos that would lead to implantation and healthy pregnancy) and a 29 percent increase in negative predictive value (identifying embyros that would not result in successful pregnancy) when compared to an external panel of embryologists."

It appears that some IVF could be eliminated by increasing the Vitamin D levels

• Women with more than minimum vitamin D were 3.4 X more likely to achieve pregnancy and 1.6 X more likely to have live births – June 2017
• Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
• Vitamin D and Human Reproduction – 51 page chapter – April 2017
• Many fertility disorders associated with low vitamin D, still unsure how much is needed – Dec 2016
• Pregnancy success increased 30 percent if sunny (or vitamin D) one month earlier – June 2015
• Preterm birth 3.3 times more likely if Vitamin D Receptor gene problem – Aug 2016
• Overview Conception and vitamin D
  • Vitamin D increases fertility of BOTH the man and the woman.
  • Each 1 ng increase in blood level of vitamin D increases fertility by 1%.
  • You may not have heard much about it since Vitamin D was patented for fertility way back in 1990.
  • Vitamin D has been used by zoos and vets for a long time to increase birth rate
• Vitamin D associated with 60 percent better assisted reproduction success – Dec 2019
• Each 1 ng increase in blood level of vitamin D increases clinical pregnancy by 6% PDF

The men need to increase Vitamin D as well

• Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
  • Note: Studies typically ignore the vitamin D level of the sprem donor
• Vitamin D somewhat assists reproduction – both the mother and the father – May 2014
• Male fertility 4 X higher if high Vitamin D – Nov 2015
• In vitro fertilization not helped by vitamin D if ignore high levels and male levels – meta Mar 2016

IVF helped by Vitamin D (if not totally eliminated)

• IVF 4X more successful for white women with lots of vitamin D – many studies
• IVF 50 percent more likely to result in pregnancy if high vitamin D – meta-analysis Nov 2017

PCOS fertility problems also reduced by VItamin D

• Fertility problem (PCOS) reduced by vitamin D, etc: many studies
• Vitamin D and aspects of female fertility (especially PCOS) – May 2017
• PCOS (polycystic ovary syndrome) 4 times more likely if poor Vitamin D Receptor – Dec 2015
  • There are many low-cost ways to increase the activation of the Vitamin D Receptor
• Vitamin D and fertility: a systematic review – May 2012 which has the following graphic

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Fertility and Sperm category contains the following summary

142 items in Fertility or Sperm in VitaminDWiki

See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D    Fertility and Vitamin D – several articles
Endometriosis
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" etc. in 18 VitaminDWiki titles

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Pregnancy category starts with

918 items in Pregnancy category

 - see also

• Overview Pregnancy and vitamin D
• Number of articles in both categories of Pregnancy and:Dark Skin 29;   Depression 21;   Diabetes 44;   Obesity 17;  Hypertension 44;   Breathing 35;  Omega-3 44;  Vitamin D Receptor 24 Click here for details
• All items in category Infant/Child 852 items
• Pregnancy needs at least 40 ng of vitamin D, achieved by at least 4,000 IU – Hollis Aug 2017
• 38+ papers with Breastfed etc, in the title
• Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019
• 53+ preeclampsia studies
• 94+ studies with PRETERM in the title
• Fertility problem (PCOS) reduced by vitamin D, etc: many studies 15+
• 94+ Gestational Diabetes
• Caesarean birth much more likely if low Vitamin D - many studies 15+ studies
• Post-partum depression and low Vitamin D - many studies 15+ studies
• Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies 5+ studies
• Search VitaminDWiki for "Assisted reproduction" 33 items as of Aug 2022
• Fertility and Sperm category listing has 142 items along with related searches
• (Stunting OR “low birth weight” OR LBW) 1180 items as of June 2020
• Less labor pain if higher level of vitamin D – August 2021
• Healthy pregnancies need lots of vitamin D
• Ensure a healthy pregnancy and baby - take Vitamin D before conception
  

Healthy pregnancies need lots of vitamin D has the following summary

Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
   Click on hyperlinks for details

Problem	Vit. D Reduces	Evidence
0. Chance of not conceiving	3.4 times	Observe
1. Miscarriage	2.5 times	Observe
2. Pre-eclampsia	3.6 times	RCT
3. Gestational Diabetes	3 times	RCT
4. Good 2nd trimester sleep quality	3.5 times	Observe
5. Premature birth	2 times	RCT
6. C-section - unplanned	1.6 times	Observe
Stillbirth - OMEGA-3	4 times	RCT - Omega-3
7. Depression AFTER pregnancy	1.4 times	RCT
8. Small for Gestational Age	1.6 times	meta-analysis
9. Infant height, weight, head size      within normal limits		RCT
10. Childhood Wheezing	1.3 times	RCT
11. Additional child is Autistic	4 times	Intervention
12.Young adult Multiple Sclerosis	1.9 times	Observe
13. Preeclampsia in young adult	3.5 times	RCT
14. Good motor skills @ age 3	1.4 times	Observe
15. Childhood Mite allergy	5 times	RCT
16. Childhood Respiratory Tract visits	2.5 times	RCT

RCT = Randomized Controlled Trial

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In vitro fertilization SlideShare July 2014

• IVF by the Numbers March 2016
  "The latest SART report shows that 61,740 babies were born in the U.S. as a result of IVF in 2012. The Centers for Disease Control and Prevention (CDC) reports about 4 million births per year in the U.S., meaning 1 to 2 percent of all U.S. births annually are via IVF."

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Women often eat pinapple on IVF day (New York Times - Oct 2019)

text for image
No evidence that pinapple improves success, vs 4X improvement in IVF if have lots of VIitamin D