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Risk of Cardiovascular death decreased 5X (lowest to highest Vitamin D level)- Feb 2024

Front. Nutr., 02 February 2024 Vol 11 - 2024 https://doi.org/10.3389/fnut.2024.1328136
Changlun Hu Mei Yang*
Department of Internal Medicine, Chongqing Nanan District Traditional Chinese and Western Medicine Hospital, Chongqing, China

VDW = 15063
Background: The focus of this survey is on survey data for adults aged 20 and above, covering nine survey cycles from 2001 to 2018. Additionally, the present study explored the correlation between vitamin D concentrations and both cardiovascular disease (CVD) and all-cause mortality.

Objective: The objectives of this study were to evaluate the trend of changes in the serum 25(OH)D concentration changes in US adults during the survey period, the prevalence of vitamin D deficiency, and the current status of vitamin D dietary intake and supplementation.

Methods: In-home health interviews were performed using meticulously designed questionnaires that gathered information on demographic details, socioeconomic conditions, dietary patterns, and overall health status. Health assessments were conducted in specially designed mobile centers.1

Results: Survey data from 2001 to 2018 revealed a rise in serum 25(OH)D levels, from a weighted mean (95% CI) of 65.6 (63.8–67.4) nmol/L during 2001–2002 to 73.5 (70.4–76.5) nmol/L during 2017–2018, among US adults, while overall vitamin D deficiency rates remained stable (p = 0.152). Notably, in adults aged 20–39, 25(OH)D levels decreased (p = 0.002 for trend), and 25(OH)D deficiency increased (p = 0.003 for trend), especially among those with low incomes (deficiency >30%). Upon multivariable adjustment, an L-shaped relationship was found between serum 25(OH)D concentrations and both CVD and all-cause mortality (p < 0.001 for nonlinearity), as corroborated by sensitivity analyses.

Conclusion: From 2001 to 2018, US adults experienced a significant increase in their serum 25(OH) D concentration. However, subgroups of individuals, including young adults and individuals with lower socioeconomic status, exhibited a heightened risk of 25(OH)D deficiency. Furthermore, an L-shaped relationship was found between 25(OH)D concentration and both all-cause and CVD mortality among US adults.
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VitaminDWiki - 27 CVD Mortality studies

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30+ VitaminDWiki Cardiovascular pages have RCT in the title

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Items found: 31
Title Modified
Should not add rock Calcium to Vitamin D (after 20 year followup: 6% increase in heart problems – no surprise) – RCT May 2024 23 May, 2024
Little Vitamin D does not reduce risk of CVD – RCT meta-analysis Dec 2023 08 Feb, 2024
Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT Feb 2015 20 Jul, 2023
Afib in Finland reduced 30% by Vitamin D (3200 IU) – RCT June 2023 09 Jul, 2023
3,200 IU of daily not help much in population already having 30 ng of Vitamin D – RCT Jan 2022 27 Sep, 2022
50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT May 2022 11 Jun, 2022
Atrial Fibrillation risk reduced by 0.84 in those raising Vitamin D levels above 30 ng – RCT April 2022 04 Apr, 2022
Monthly vitamin D helped hearts with low vitamin D a bit (need it more frequently) – RCT March 2022 11 Mar, 2022
Off Topic: EDTA similar reduction in heart attack as Vitamin C, aspirin and Mg – RCT March 2013 04 Jan, 2022
Chronic Heart Failure reduced by 4,000 IU daily for a year – RCT April 2016 07 Oct, 2021
Cardiovascular Disease prevented by Vitamin K2-4 when enough is used – RCT review Sept 2020 27 Feb, 2021
50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014 24 Nov, 2018
Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT Sept 2018 10 Sep, 2018
Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT May 2018 17 May, 2018
Open Heart Surgery associated with low vitamin D, but not if 150,000 IU before surgery – RCT March 2018 13 Mar, 2018
3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT March 2018 13 Mar, 2018
Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT Nov 2017 18 Nov, 2017
Heart Failure Quality of Life greatly improved by 10,000 IU of vitamin D – RCT Oct 2017 01 Nov, 2017
Anemia (in heart failure) not treated by Vitamin D (they should have added Iron) – RCT Aug 2017 25 Aug, 2017
Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT July 2017 09 Aug, 2017
Heart Failure not helped by Vitamin D (several strange things about the trial) – RCT May 2017 24 May, 2017
Why 100,000 IU of vitamin D monthly did not reduce Cardiovascular Disease – RCT April 2017 06 Apr, 2017
Decreased need for warfarin after Vitamin D levels optimized – RCT May 2016 04 Jul, 2016
Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT Feb 2012 20 Oct, 2015
If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT May 2015 22 May, 2015
Heart failure markers reduced by 400 IU of vitamin D and Calcium (surprise) – RCT Jan 2015 18 Mar, 2015
More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT Oct 2013 16 Mar, 2015
4000 IU vitamin D daily for just 5 days reduced inflammation after heart attack – RCT Jan 2013 16 Mar, 2015
1700 IU vitamin D for a year provided no cardiovascular benefit (no surprise) – RCT Oct 2014 01 Nov, 2014
Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT Aug 2014 25 Jul, 2014
Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT June 2013 30 Jun, 2013

shorturl = https://is.gd/cvdmort

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