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Cancer mortality not reduced by small vitamin D doses - Sept 2021

Vitamin D Supplementation and Cancer Mortality: Narrative Review of Observational Studies and Clinical Trials

Nutrients 2021, 13, 3285. https://doi.org/10.3390/ nu13093285
Patrizia Gnagnarella 1,*, Valeria Muzio 1, Saverio Caini 2, Sara Raimondi 3, Chiara Martinoli 3, Susanna Chiocca 3, Claudia Miccolo 3, Paolo Bossi 4, Diego Cortinovis 5, Ferdinando Chiaradonna 6, Roberta Palorini 6, Federica Facciotti 3, Federica Bellerba 3, Stefania Canova 5 and Sara Gandini 3


They found success in trials using 8,000 IU of vitamin D

Mortality in VitaminDwiki starts with:

People die sooner if they have low vitamin D
Mortality is.gd/VitaminDMortality
click on image for details

More vitamin D means fewer deaths – many studies

There are 316 articles in Mortality category

Cancer category starts with the following

Cancers get less Vitamin D when there is a poor Vitamin D Receptor

 Download the PDF from VitaminDWiki

Several studies have investigated the beneficial effects of vitamin D on survival of cancer patients. Overall evidence has been accumulating with contrasting results. This paper aims at narratively reviewing the existing articles examining the link between vitamin D supplementation and cancer mortality. We performed two distinct searches to identify observational (ObS) studies and randomized clinical trials (RCTs) of vitamin D supplementation (VDS) in cancer patients and cohorts of general population, which included cancer mortality as an outcome. Published reports were gathered until March 2021. We identified 25 papers published between 2003 and 2020, including n. 8 RCTs on cancer patients, n. 8 population RCTs and n. 9 ObS studies. There was some evidence that the use of VDS in cancer patients could improve cancer survival, but no significant effect was found in population RCTs. Some ObS studies reported evidence that VDS was associated with a longer survival among cancer patients, and only one study found an opposite effect. The findings do not allow conclusive answers. VDS may have the potential as treatment to improve survival in cancer patients, but further investigations are warranted. We strongly support investment in well- designed and sufficiently powered RCTs to fully evaluate this association.

Created by admin. Last Modification: Tuesday September 21, 2021 12:19:27 GMT-0000 by admin. (Version 5)

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16250 Vitamin D Cancer Mortality.pdf admin 21 Sep, 2021 399.39 Kb 256