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Cancer and Vitamin D - many studies


79 Meta-analyses in VitaminDWiki with CANCER etc in title (Oct 2022)

This list is automatically updated

Items found: 79
Title Modified
Colorectal Cancer 10 percent more likely if poor Vitamin D Receptor – meta-analysis Jan 2023 08 Jan, 2023
Melanoma might be suppressed by Vitamin D - many studies 25 Nov, 2022
Thyroid Cancer 1.4 X higher risk if low vitamin D– meta-analysis Feb 2018 12 Oct, 2022
Colorectal cancer 14 percent less likely if 10 ng more Vitamin D – 22nd meta-analysis – Sept 2022 13 Sep, 2022
USPSTF says no evidence that Vitamins prevent CVD or Cancer (data disagrees) Aug 2022 05 Sep, 2022
Even after a Cancer diagnosis Vitamin D improves survival – meta-analysis Aug 2022 19 Aug, 2022
Colorectal cancer 40 percent less likely if 1000 IU more Vitamin D – 21st meta-analysis – Oct 2021 29 Oct, 2021
Colorectal cancer 25 percent less likely if good level of Vitamin D – 20th meta-analysis – June 2021 02 Jul, 2021
Lung Cancer death 40 percent less likely if high level of Vitamin D – meta-analysis Nov 2020 24 Nov, 2020
Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020 09 Nov, 2020
Vitamin D fights 13 cancers – review of 35 meta-analyses – Oct 2020 06 Oct, 2020
Breast Cancer again associated with low vitamin D – 15th meta-analysis Sept 2020 02 Oct, 2020
Colorectal cancer treated by Vitamin D – 19th meta-analysis – Sept 2020 17 Sep, 2020
3X less risk of Liver cancer if more than 30 ng of vitamin D – meta-analysis July 2020 28 Jul, 2020
Liver Cancer 8 percent less likely for every 4 ng higher level of vitamin D – Meta-analysis April 2020 02 Apr, 2020
Melanoma 2.1 X more likely if low vitamin D – meta-analysis Jan 2020 11 Jan, 2020
Breast Cancer risk reduced 17 percent by 1 hour of daily summer sun – meta-analysis Jan 2020 07 Jan, 2020
Liver Cancer – higher risk if poor genes (Vitamin D receptor etc) – meta-analysis Dec 2019 14 Dec, 2019
Colon cancer both prevented and treated by Vitamin D – meta-analysis Dec 2019 04 Dec, 2019
Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016 09 Nov, 2019
Cancer with low Vitamin D increases Mortality by 13 percent – meta-analysis Feb 2019 05 Jul, 2019
People supplemented with Vitamin D had 13 percent fewer Cancer deaths – Meta-analysis of RCT June 2019 05 Jul, 2019
Breast Cancer rate reduced by 40 percent with Omega-3 – meta-analysis June 2013 16 Jun, 2019
Lung Cancer more likely if poor Vitamin D Receptor – meta-analysis June 2019 13 Jun, 2019
Variety of Vitamin D forms treat Prostate Cancer – RCT Review April 2019 01 May, 2019
Pancreatic cancer risk of death reduced 19 percent by Vitamin D – meta-analysis June 2017 20 Mar, 2019
Breast Cancer reduced 20 percent by fish (Omega-3) – meta-analysis Feb 2019 05 Mar, 2019
Prostate Cancer death 40 percent less likely if 40 ng level of vitamin D – Meta-analysis Oct 2018 14 Oct, 2018
16 percent less Prostate Cancer sometimes for each 10 ng vitamin D increase - meta-analysis Jan 2011 13 Oct, 2018
Lung Cancer risk decreased 2.4 percent with every 100 IU Vitamin D extra intake – meta-analysis Sept 2018 15 Sep, 2018
Colorectal cancer is associated with Vitamin D (17 meta-analyses so far) – July 2018 18 Jul, 2018
Thyroid Cancer 1.3X higher risk if low vitamin D (yet again) – meta-analysis June 2018 02 Jun, 2018
Cancer not treated by Vitamin D when ignore dose size, type, and length of trial – meta-analysis April 2018 09 Apr, 2018
Pancreatic cancer risk reduced 25 percent by just 10 micrograms of Vitamin D or Vitamin B12 – meta-analysis March 2018 30 Mar, 2018
Prostate cancer risk increase with Vitamin D (other studies disagree) – meta-analysis Jan 2018 11 Jan, 2018
Lung Cancer death 60 percent less likely if high level of vitamin D – 2 meta-analysis 2017 29 Dec, 2017
Ovarian Cancer in Asia is 1.5 X more likely if poor Vitamin D receptor – meta-analysis Dec 2017 14 Dec, 2017
Lung Cancer patients were 2.4 times more likely to have a poor Vitamin D Receptor gene – July 2017 27 Jul, 2017
Lymphoma, leukemia etc, survival poor if low vitamin D – meta-analysis March 2015 06 Jul, 2017
Lung Cancer less likely if vitamin D (higher level or supplement) – meta-analysis May 2015 06 Jul, 2017
Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017 13 Jun, 2017
Lung Cancer risk decreases 5 percent for every 2.5 nanogram increase in Vitamin D – meta-analysis Sept 2015 22 Feb, 2017
Colorectal cancer 60 percent less likely: high vs low Vitamin D level – meta-analysis Dec 2016 22 Dec, 2016
Colorectal Cancer recurrence not prevented by 1,000 IU of vitamin D – meta-analysis Dec 2016 09 Dec, 2016
Bladder cancer modifiable risk factors include low vitamin D – meta-analysis March 2016 08 Dec, 2016
Bladder cancer 60 percent less likely if have high vitamin D – meta-analysis Dec 2015 08 Dec, 2016
Vitamin D receptor polymorphisms are risk factors for various cancers – meta-analysis Jan 2014 12 Nov, 2016
10 percent of colon cancer linked to Vitamin D Receptor – meta-analysis April 2012 23 Sep, 2016
Kidney cancer 22 percent less likely if high vitamin D – meta-analysis Nov 2015 30 Mar, 2016
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis April 2015 24 Dec, 2015
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis Oct 2014 24 Dec, 2015
Non-cancer colon growths 7 percent less likely with each 10 ng increase in vitamin D – Oct 2011 31 Oct, 2015
Cancer risk weakly associated with vitamin D-binding protein – meta-analysis Sept 2015 15 Oct, 2015
Meta-graphs of vitamin D and Cancer – Dec 2011 20 Sep, 2015
Colon cancer 30 percent more likely if low vitamin D – 12th meta-analysis Aug 2015 14 Aug, 2015
Obesity causes 20 percent of all cancer, low vitamin D may be the connection – meta-analysis - Sept 2014 31 May, 2015
Increased risk of some female cancers if low vitamin D (due to genes) – meta-analysis June 2015 03 May, 2015
Colon cancer risk reduced by many vitamins – 13 percent reduction by Vitamin D – meta-analysis Jan 2015 11 Dec, 2014
Breast Cancer – review of 2 RCT did not find association with 1000 IU of Vitamin D – July 2013 16 Nov, 2014
Cancer (colon, breast, lymph) survival about 2X better with high level vitamin D – meta-analysis July 2014 30 Sep, 2014
Colorectal and Breast Cancer – Vitamin D is associated with fewer deaths – meta-analysis Feb 2014 30 Sep, 2014
Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014 12 May, 2014
More survive Breast Cancer if more vitamin D – 2X fewer deaths with just 30 ng -meta-analysis March 2014 08 May, 2014
Death of women from cancer 24 percent less likely if 20 ng more vitamin D – meta-analysis Sept 2013 01 May, 2014
Death due to breast cancer reduced 40 percent if high vitamin D – meta-analysis April 2014 08 Apr, 2014
Breast Cancer survival 2X more likely if vitamin D sufficient – meta-analysis May 2013 06 Mar, 2014
Breast Cancer post menopause down 12 percent for every 5 ng of vitamin D – meta-analysis May 2013 28 Oct, 2013
Probably need more than 1000 IU of vitamin D to prevent cancer – meta-analysis Aug 2013 20 Aug, 2013
3.2 percent less Breast Cancer for 2.4 ng more vitamin D – meta-analysis June 2013 08 Jul, 2013
Colorectal cancer 26 percent less likely for every 10 ng of vitamin D – meta-analysis Aug 2011 10 Nov, 2012
Breast cancer association with low vitamin D suggested by Meta-analysis -April 2010 19 Jul, 2012
Colon cancer probability increases with decreased vitamin D – Meta-analysis July 2011 23 Jun, 2012
Vitamin D has a complex relationship with Cancer – meta-analysis July 2011 30 Sep, 2011
Meta-analysis of 3 cancers - 10 ng more vitamin D decrease colorectal by 15 percent– May 2010 31 Aug, 2011
Risk of Prostate Cancer weakly associated with vitamin D - meta-analysis March 2011 11 Aug, 2011
Meta-analysis found vitamin D association with colon but not prostate nor breast cancer May 2010 17 Jan, 2011
Meta-analysis not find low vitamin D years before breast cancer – Aug 2010 10 Sep, 2010
Meta-analysis confirmed that vitamin D and calcium prevents breast cancer – June 2010 30 Aug, 2010
Meta-analysis did not find strong association between vitamin D and breast cancer risk -April 2010 12 May, 2010

30 Intervention trials in VitaminDWiki with CANCER etc in title (Oct 2022)

This list is automatically updated

Items found: 31
Title Modified
After Colorectal Cancer Surgery the immune system was maintained by Vitamin D (8,000 IU daily) – RCT Jan 2023 03 Jan, 2023
Cancer risk reduced 65 percent by vitamin D levels greater than 40 nanograms – April 2016 31 Dec, 2022
2.5 X reduced risk of cancer in 70 year-olds by a small amount of Vitamin D, Omega-3 and exercise – RCT April 2022 25 Apr, 2022
Breast Cancer not prevented by 1,000 IU of Vitamin D (no surprise) – RCT Aug 2021 14 Apr, 2022
Rectal Cancer genes down-regulated by Vitamin D (3,200 IU only helped some) – RCT Aug 2021 03 Aug, 2021
Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019 25 Jul, 2021
Digestive Tract Cancer survival increased 3X if 2,000 IU of vitamin D and have high level of PD-L1 – RCT June 2021 29 Jun, 2021
Prostate Cancer PSA reduced by 60 ng of Vitamin D, Vitamin B complex, Omega-3, Curcumin and diet – June 2021 20 Jun, 2021
2,000 IU of vitamin D and Omega-3 reduced Cancer death rate bv 1.7X (normal weight) – VITAL RCT Nov 2020 03 Dec, 2020
Breast Cancer chemo reduces Bone Mineral Density, injecting Vitamin D increases it – Sept 2019 07 Sep, 2019
Multiple Myeloma (blood cell cancer) treated by vitamin D - many studies 14 Jun, 2019
After breast cancer treatment 4,000 IU of Vitamin D was not enough to help if have poor Vitamin D receptor – June 2019 04 Jun, 2019
Digestive tract cancer death rates reduced a bit by a bit of vitamin D – RCT April 2019 10 Apr, 2019
Advanced Colorectal Cancer survival is increased somewhat with 4,000 IU of vitamin D – RCT April 2019 10 Apr, 2019
Vitamin D and Omega-3 Ineffective for Preventing Cancer and Heart Disease (too little was used) – Nov 2018 21 Nov, 2018
Lung cancer treated by Vitamin D (1200 IU early stage) – RCT July 2018 04 Sep, 2018
Liver cancer nicely treated by high dose vitamin D for 16 weeks (early stage, in rats) – April 2018 23 Apr, 2018
Prostate Cancer might be treated by 4,000 IU of vitamin D and aspirin – RCT 2021 28 Nov, 2017
Lymphoid cancer deaths cut in half with 400 IU of vitamin D and 1 gram of Calcium (WHI) – RCT Nov 2017 04 Nov, 2017
Perhaps Breast Cancer tumors can be reduced by 7 weeks of 50,000 IU Vitamin D – 2023 23 Oct, 2017
Prostate Cancer treatment (Vitamin D, Omega-3, Tumeric) RCT ending Dec 2018 26 Sep, 2017
Palliative cancer benefit of 4,000 IU of Vitamin D – less opioids, infection, and CRP – Aug 2017 01 Sep, 2017
People with metastatic melanoma and initially Vitamin D deficient had 4.7 times worse outcome if not get enough D – Dec 2016 31 Dec, 2016
Low risk Prostate Cancer decreased with 4,000 IU of vitamin D – July 2012 21 Dec, 2015
Colon Cancer proven again to not be treated by just 1000 IU of vitamin D – RCT Oct 2015 20 Oct, 2015
Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT June 2012 24 May, 2015
Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT April 2015 02 Apr, 2015
Active form of vitamin D appears to help prevent and treat some cancers – Feb 2011 16 Mar, 2015
Not enough women willing to stop taking vitamin D to permit breast cancer clinical trial – June 2012 14 Mar, 2015
Breast Cancer reduced 20 percent by just 400 IU of vitamin D plus Calcium – 2011 15 Nov, 2014
Mayo clinic starting Cancer RCT using grossly inadequate 2,000 IU of vitamin D – Sept 2013 04 Dec, 2013

18 Omega-3 VitaminDWiki studies with CANCER etc in title (Oct 2022)

This list is automatically updated

Items found: 18
Title Modified
2.5 X reduced risk of cancer in 70 year-olds by a small amount of Vitamin D, Omega-3 and exercise – RCT April 2022 25 Apr, 2022
Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019 25 Jul, 2021
Prostate Cancer PSA reduced by 60 ng of Vitamin D, Vitamin B complex, Omega-3, Curcumin and diet – June 2021 20 Jun, 2021
Men with High Omega-3 ratio 3 times less likely to have high grade prostate cancer – July 2019 20 Jul, 2019
Omega-3 reduces side effects of Cancer treatments – April 2019 25 Jun, 2019
Omega-3 reduced by 4X the interruption of Cervical Cancer chemotherapy due to toxicity – RCT June 2019 18 Jun, 2019
Breast Cancer rate reduced by 40 percent with Omega-3 – meta-analysis June 2013 16 Jun, 2019
Omega-3 Reduces risk of Breast Cancer 24 May, 2019
Breast Cancer reduced 20 percent by fish (Omega-3) – meta-analysis Feb 2019 05 Mar, 2019
Vitamin D and Omega-3 Ineffective for Preventing Cancer and Heart Disease (too little was used) – Nov 2018 21 Nov, 2018
Pancreatic Cancer is increasing – Vitamin D and Omega-3 should reduce the risk 23 Jul, 2018
Low-Grade Prostate Cancer 70 percent less likely to progress if good level of Omega-3 – June 2018 10 Apr, 2018
Increasing Omega-3 reduces heart problems, autism, depression, preterm birth, breast cancer, etc. 15 Dec, 2017
Prostate Cancer treatment (Vitamin D, Omega-3, Tumeric) RCT ending Dec 2018 26 Sep, 2017
Omega-3 prevents and treats several cancers – Sept 2017 23 Sep, 2017
Breast cancer and Omega-3 – perhaps prevention and augment treatment – Aug 2017 08 Aug, 2017
Omega-3 should help Pancreatic Cancer in 5 ways – June 2017 25 Jun, 2017
Breast cancer cells killed synergistically by Vitamin D plus Omega-3 (lab) – June 2017 20 Jun, 2017

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VitaminDWiki – Cancer category contains


Cancers get less Vitamin D when there is a poor Vitamin D Receptor


VitaminDWiki – Cancer increases if poor Vitamin D Receptor

Cancers get less Vitamin D when there is a poor Vitamin D Receptor


VitaminDWiki – Cancer - After diagnosis category contains

  • Most cancers reduce vitamin D levels
  • Most cancer treatments (chemo, radiation) further lower Vit D
  • Higher levels of vitamin D minimize many side-effects of cancer therapy
  • High levels of vitamin D augment many chemotherapies
  • High levels of vitamin D can kill some cancer cells >1,000 items 07/2018
  • Some cancers disable standard vitamin D metabolism

Example VitaminDWiki Studies


Vitamin D in Cancer Prevention: Gaps in Current Knowledge and Room for Hope - Oct 2022

Nutrients 2022, 14(21), 4512; https://doi.org/10.3390/nu14214512
by Matthias Henn et. al
(This article belongs to the Special Issue The Role of Vitamin D in Cancer Prevention) - which includes

  • Vitamin D and Risk of Obesity-Related Cancers: Results from the SUN (‘Seguimiento Universidad de Navarra’) Project
  • A Phase II Multicenter Trial on High-Dose Vitamin D Supplementation for the Correction of Vitamin D Insufficiency in Patients with Breast Cancer Receiving Adjuvant Chemotherapy
  • Prevention of Advanced Cancer by Vitamin D3 Supplementation: Interaction by Body Mass Index Revisited
  • The Controversial Role of Vitamin D in Thyroid Cancer Prevention

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Table of Contents
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Intensive epigenome and transcriptome analyses have unveiled numerous biological mechanisms, including the regulation of cell differentiation, proliferation, and induced apoptosis in neoplastic cells, as well as the modulation of the antineoplastic action of the immune system, which plausibly explains the observed population-based relationship between low vitamin D status and increased cancer risk. However, large randomized clinical trials involving cholecalciferol supplementation have so far failed to show the potential of such interventions in cancer prevention. In this article, we attempt to reconcile the supposed contradiction of these findings by undertaking a thorough review of the literature, including an assessment of the limitations in the design, conduct, and analysis of the studies conducted thus far. We examine the long-standing dilemma of whether the beneficial effects of vitamin D levels increase significantly above a critical threshold or if the conjecture is valid that an increase in available cholecalciferol translates directly into an increase in calcitriol activity. In addition, we try to shed light on the high interindividual epigenetic and transcriptomic variability in response to cholecalciferol supplementation. Moreover, we critically review the standards of interpretation of the available study results and propose criteria that could allow us to reach sound conclusions in this field. Finally, we advocate for options tailored to individual vitamin D needs, combined with a comprehensive intervention that favors prevention through a healthy environment and responsible health behaviors.
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See also VitaminDWiki

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569,000 hits for search of: Cancer "vitamin d" (supplementation OR RCT OR trial)

Google Scholar Oct 2022)


Created by admin. Last Modification: Saturday November 12, 2022 22:17:38 GMT-0000 by admin. (Version 33)

Attached files

ID Name Comment Uploaded Size Downloads
18718 Vit D Cancer genes.jpg admin 27 Oct, 2022 17:09 171.15 Kb 77
18717 ToCCancer prevention.jpg admin 27 Oct, 2022 14:06 63.37 Kb 54
18716 Cancer meta.jpg admin 27 Oct, 2022 14:06 133.91 Kb 133
18714 Cancer prevention Oct 2022_CompressPdf.pdf PDF 2022 admin 27 Oct, 2022 14:05 422.66 Kb 22