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Blood pressure reduced if take more than 4.5 grams of Omega-3 daily– umbrella meta-analysis Aug 2022


The beneficial effects of omega-3 polyunsaturated fatty acids on controlling blood pressure: An umbrella meta-analysis

Front. Nutr., 18 August 2022. https://doi.org/10.3389/fnut.2022.985451
Vali Musazadeh1,2, Zeynab Kavyani1,2, Behnaz Naghshbandi3, Parvin Dehghan4* and Mahdi Vajdi5,6*
1 Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Community Nutrition, School of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Food Science and Technology, North Tehran Branch, Islamic Azad University, Tehran, Iran
4 Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5 Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
6 Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran

Several meta-analyses have revealed that n-3 PUFAs can lower blood pressure, but the findings are conflicting. In this regard, the present umbrella meta-analysis aimed was performed to clarify whether n-3 PUFAs have effects on blood pressure. PubMed, Scopus, Embase, Web of Science, and Google Scholar were used as international databases from inception to May 2022. To examine the effects of n-3 PUFA supplementation on blood pressure, a random-effects model was applied. The leave-one-out method was performed for the sensitivity analysis. The pooled estimate of 10 meta-analyses with 20 effect sizes revealed significant reductions in both systolic (ES = −1.19 mmHg; 95% CI: −1.76, −0.62, p < 0.001) and diastolic blood pressure (ES = −0.91 mmHg, 95% CI: −1.35, −0.47; p < 0.001) following n-3 PUFAs supplementation. In studies with a sample size of ≤ 400 participants and a mean age over 45, SBP and DBP were found to be substantially reduced. Overall, this umbrella meta-analysis indicates that n-3 PUFAs supplementation might play a role in improving DBP and SBP.
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VitaminDWiki - 4 studies in both categories Hypertension and Omega-3

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VitaminDWiki - 23 studies in both categories Hypertension and Meta-analysis

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VitaminDWiki - Hypertension category listing contains

164 items in the category HYPERTENSION

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VitaminDWiki - Omega-3 helps many health problems

394 Omega-3 items in category Omega-3 helps with: Autism (8 studies), Depression (29 studies), Cardiovascular (34 studies), Cognition (49 studies), Pregnancy (40 studies), Infant (32 studies), Obesity (13 studies), Mortality (7 studies), Breast Cancer (5 studies), Smoking, Sleep, Stroke, Longevity, Trauma (12 studies), Inflammation (18 studies), Multiple Sclerosis (9 studies), VIRUS (12 studies), etc
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Created by admin. Last Modification: Friday September 23, 2022 20:54:53 GMT-0000 by admin. (Version 4)

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18472 BP Omega-3 umbrella meta_CompressPdf.pdf admin 23 Sep, 2022 210.44 Kb 79