Even better: 50,000 IU of vitamin D every 12 days starting a month before pregnancy
Table of contents
- Effect of Maternal Supplementation with Two Different Doses of Vitamin D During Lactation on Vitamin D Status, Anthropometry and Bone Mass of Infants: A Randomized Controlled Trial
- 39+ VitaminDWiki pages have BREASTFED or BREASTFEEDING in the title
- VitaminDWiki - Pregnancy category contains:
- VitaminDWiki - Healthy pregnancies need lots of vitamin D
- VitaminDWiki - Weekly, Monthly Vitamin D are typically better than daily - many studies
Effect of Maternal Supplementation with Two Different Doses of Vitamin D During Lactation on Vitamin D Status, Anthropometry and Bone Mass of Infants: A Randomized Controlled Trial
Indian Pediatr. 2022 Jan 9;S09747559160039
Rekha Ramot 1, Swati Yadav 2, S K Vishnoi 2, Pramod Sharma 2, Rajesh Khadgawat 1, Rakesh Jora 3
Background: There is a high prevalence of vitamin D deficiency (VDD) in exclusively breast-fed infants in the absence of appropriate vitamin D supplementation.
Objective: To evaluate the efficacy of two doses of maternal vitamin D supplementation on vitamin D levels of mother-infant pairs and to assess its effect on growth parameters(weight, length and head circumference) and bone mass of infants.
Study design: Randomized controlled trial.
Participants: Lactating mother-infant pairs (n=220).
Intervention: Maternal oral vitamin D supplementation in two doses (group 1: 120 000 IU/month and group 2: 12000 IU/month for 12 months.
Main-outcomes: Maternal and infant serum 25OHD levels, and infant's growth and bone mass.
Results: There was high prevalence of VDD at baseline in mothers (94%) as well as infants (98.5%) which was reduced to 43.1% in (mothers) and 46.5% in infants after 12 months. Significantly higher median (IQR) serum 25OHD levels (ng/mL) were observed among mothers in group 1 compared to group 2 [46 (17-159) vs 18 (6-64); P<0.01] and in infants [36.5 (15-160) vs 17 (7-32); P<0.01]. No significant association was observed between growth parameters or bone mass and serum 25OHD levels of mother or infant between the two groups. Four mothers (3.6%) and two infants (1.8%) in group I had serum 25OHD>100 ng/mL, but without hypercalciuria or hypercalcemia.
Conclusion: Bolus vitamin D supplementation in the dose of 1,20,000IU/month was more efficacious in improving maternal and infant vitamin D status at 12 months, as compared to 12,000 IU/month.
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39+ VitaminDWiki pages have BREASTFED or BREASTFEEDING in the title
This list is automatically updated
VitaminDWiki - Pregnancy category contains:
942 items in Pregnancy category- see also
- Overview Pregnancy and vitamin D
- Number of articles in both categories of Pregnancy and:Dark Skin 30; Depression 21; Diabetes 45; Obesity 18; Hypertension 44; Breathing 37; Omega-3 46; Vitamin D Receptor 25 Click here for details
- All items in category Infant/Child 867 items
- Pregnancy needs at least 40 ng of vitamin D, achieved by at least 4,000 IU – Hollis Aug 2017
- 38+ papers with Breastfed etc, in the title
- Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019
- 53+ preeclampsia studies
- 94+ studies with PRETERM in the title
- Fertility problem (PCOS) reduced by vitamin D, etc: many studies 15+
- 94+ Gestational Diabetes
- Caesarean birth much more likely if low Vitamin D - many studies 15+ studies
- Post-partum depression and low Vitamin D - many studies 15+ studies
- Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies 5+ studies
- Search VitaminDWiki for "Assisted reproduction" 33 items as of Aug 2022
- Fertility and Sperm category listing has 146 items along with related searches
- (Stunting OR “low birth weight” OR LBW) 1180 items as of June 2020
- Less labor pain if higher level of vitamin D – August 2021
- Healthy pregnancies need lots of vitamin D
- Ensure a healthy pregnancy and baby - take Vitamin D before conception
VitaminDWiki - Healthy pregnancies need lots of vitamin D
Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
Click on hyperlinks for details
Problem | Vit. D Reduces | Evidence |
0. Chance of not conceiving | 3.4 times | Observe |
1. Miscarriage | 2.5 times | Observe |
2. Pre-eclampsia | 3.6 times | RCT |
3. Gestational Diabetes | 3 times | RCT |
4. Good 2nd trimester sleep quality | 3.5 times | Observe |
5. Premature birth | 2 times | RCT |
6. C-section - unplanned | 1.6 times | Observe |
Stillbirth - OMEGA-3 | 4 times | RCT - Omega-3 |
7. Depression AFTER pregnancy | 1.4 times | RCT |
8. Small for Gestational Age | 1.6 times | meta-analysis |
9. Infant height, weight, head size within normal limits | RCT | |
10. Childhood Wheezing | 1.3 times | RCT |
11. Additional child is Autistic | 4 times | Intervention |
12.Young adult Multiple Sclerosis | 1.9 times | Observe |
13. Preeclampsia in young adult | 3.5 times | RCT |
14. Good motor skills @ age 3 | 1.4 times | Observe |
15. Childhood Mite allergy | 5 times | RCT |
16. Childhood Respiratory Tract visits | 2.5 times | RCT |
RCT = Randomized Controlled Trial