Total Duration of Breastfeeding, Vitamin D Supplementation, and Serum Levels of 25-Hydroxyvitamin D
Vitamin D needed is proportional to weight
As the infant gets older more vitamin D is needed
100 IU per kg of infant July 2011, Poland etc.
6400 IU of vitamin D for mother during lactation provides barely enough vitamin D for a small infant
- Fewer pre-infants were vitamin D deficient when they got 800 IU – RCT Feb 2014
- Breastfed infants: 90 percent had less than 20 ng of vitamin D, formula-fed: 15 percent – May 2013
- Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT May 2013
- Infant-Child category listing has
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Denise Darmawikarta, MPH, Yang Chen, MA, MSc, Gerald Lebovic, PhD, Catherine S. Birken, MD, MSc, Patricia C. Parkin, MD, and Jonathon L. Maguire, MD, MSc
Denise Darmawikarta, Yang Chen, Gerald Lebovic and Jonathan L. Maguire are with the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada. Catherine S. Birken, Patricia C. Parkin, and Jonathon L. Maguire are with the Department of Pediatrics, Hospital for Sick Children, Toronto, and the Department of Pediatrics, University of Toronto.
Correspondence should be sent to Jonathon Maguire, MD, MSc, FRCPC, Department of Pediatrics, St Michael’s Hospital, 30 Bond St, 15-CC-014, Toronto ON M5B 1W8, Canada (e-mail: jonathon.maguire at utoronto.ca).
D. Darmawikarta, Y. Yang, C. S. Birken, P. C. Parkin, and J. L. Maguire conceptualized and designed the study, designed the data collection instruments, and analyzed and interpreted the data. D. Darmawikarta, Y. Yang, and G. Lebovic performed the statistical analysis. D. Darmawikarta and J. L. Maguire drafted the article. All authors critically reviewed and revised the article for important intellectual content and approved the final article as submitted.ABSTRACT
Objectives. To determine the association between total breastfeeding duration and serum 25-hydroxyvitamin D (25-OHD) and to explore whether vitamin D supplementation influences this association.Methods. We conducted a cross-sectional study of healthy children between September 2011 and August 2013 through the TARGet Kids! primary health care research network. Of the 4533 eligible children, we included only the 2508 who had 25-OHD measured. We assessed adjusted associations of total breastfeeding duration (in months) with serum 25-OHD and in supplemented versus nonsupplemented children, with the odds of 25-OHD less than 20 nanograms per milliliter.
Results. Each 1-month increase in total breastfeeding duration was associated with a 0.12 nanograms per milliliter lower median serum 25-OHD (95% confidence interval [CI] = –0.21 ng/mL, –0.02 ng/mL) among children who were not supplemented. The odds of serum 25-OHD less than 20 nanograms per milliliter increased by 6% (odds ratio [OR] = 1.06; 95% CI = 1.03, 1.10) for every 1-month increase in total breastfeeding duration among nonsupplemented children. The interaction between vitamin D supplementation, duration of breastfeeding, and median serum 25-OHD was statistically significant (P = .04).
Conclusions. Breastfed children who were not supplemented, particularly those breastfed more than 1 year, appear to have lower vitamin D status. Vitamin D supplementation may mitigate this risk. These findings support recommendations for supplementation during breastfeeding of any duration. (Am J Public Health. Published online ahead of print February 18, 2016: e1–e6. doi:10.2105/AJPH.2015.303021)
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Breastfed child needs even more vitamin D supplementation after 1 year – Feb 20165520 visitors, last modified 28 Feb, 2016, This page is in the following categories (# of items in each category)