Their title, not mine
Archives of Gynecology and Obstetrics – Aug 2014
Raffaella Mormile, Vassilios Fanos, Giorgio Vittori
1 Division of Pediatrics and Neonatology, Moscati Hospital, Via A. Gramsci, 3, 81031, Aversa, Italy, raffaellamormile at alice.it.
Free excerpt: Publisher wants $45 for PDF
Great advances in neonatal intensive care have improved survival rates of infants who once had little chance for survival such as preterm babies [1, 2]. Organ system immaturity in preterm infants is connected with long term complications that have both clinical and public health importance [1]. Severe hypoxia occurs in most preterm infants leading to cell death which may be necrotic or apoptotic [1]. Significant elevation of apoptotic activity has been shown to play a prominent role in the pathogenesis of several diseases associated with prematurity such as renal dysfunction [1]. In the kidneys of preterm infants, apoptosis has been described in tubular epithelial cells [1]. Renal tubular cell apoptosis has been shown to play a critical role in the pathogenesis of acute renal failure [3]. The consequences of premature birth or low birth weight on nephrogenesis, final nephron number and long-term kidney function are still not well defined [2].The kidney of low birth weight preterm infan . . .
References
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VitaminDWiki believes that the history does not have to be re-written.
However, the current recommendations need to be increased to face the reality that virtually EVERYONE now has less vitamin D.
Reasons for Vitamin D deficiency 34 reasons as of 2014
See also VitaminDWiki
- Vitamin D Deficiency
- Incidence of 22 health problems related to vitamin D have doubled in a decade
- Does Less Sun mean More Disease short video produced by VitaminDWiki
- Overview of Rickets and Vitamin D
- Overview Pregnancy and vitamin D has the following summary
| IU | Cumulative Benefit | Blood level | Cofactors | Calcium | $*/month |
| 200 | Better bones for mom with 600 mg of Calcium | 6 ng/ml increase | Not needed | No effect | $0.10 |
| 400 | Less Rickets (but not zero with 400 IU) 3X less adolescent Schizophrenia Fewer child seizures | 20-30 ng/ml | Not needed | No effect | $0.20 |
| 2000 | 2X More likely to get pregnant naturally/IVF 2X Fewer dental problems with pregnancy 8X less diabetes 4X fewer C-sections (>37 ng) 4X less preeclampsia (40 ng vs 10 ng) 5X less child asthma 2X fewer language problems age 5 | 42 ng/ml | Desirable | < 750 mg | $1 |
| 4000 | 2X fewer pregnancy complications 2X fewer pre-term births | 49 ng/ml | Should have cofactors | < 750 mg | $3 |
| 6000 | Probable: larger benefits for above items Just enough D for breastfed infant More maternal and infant weight | Should have cofactors | < 750 mg | $4 |
Just the TOP articles in Infant-Child and Vitamin D are listed here:
- COVID 5.5 X more likely to be severe if low Vitamin D (children in this case) – Oct 2022
- COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
- Vitamin D levels in new borns are so low that they are considering supplementing to prevent Rickets (Japan) – July 2022
- Problems after childhood vaccinations - many studies
- Remdesivir approved to treat COVID in Infants, yet Vitamin D is 3000 X more cost effective and widely used - April 2022
- High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis April 2022
- 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine - Dec 15, 2021
- Childhood cancers – give Vitamin D loading dose if low – Oct 2021
- 36X more likely for an infant to be low vitamin D if exclusively breastfed (Hong Kong) – March 2021
- Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT July 2021
- Vitamin D toxicity is extremely rare, accidental, and very mild in Iranian children – July 2020
- Breastfeeding a child without adding vitamin D increases risk of many food allergies (egg whites in this case) – Jan 2020
- Vitamin D compliance 3X higher when children with fractures actually knew their low vitamin D level – March 2019
- Vitamin D levels have been crashing since 1995 (Polish Children, Elite Military, etc)
- Infant Vitamin D – JAMA said 1600 IU, Europe says 1,000 IU upper limit – June 2018
- Children no longer get much vitamin D from milk - fortify at home
- 10 Reasons why children no longer have healthy levels of Vitamin D
- Only 1 in 6 infants got even 400 IU of vitamin D daily – June 2018
- Vitamin D supplementation by only 1 in 60 US Children – JAMA June 2018
- Adding Vitamin D, Omega-3, etc to children’s milk improved memory (yet again) – RCT June 2018
- Child Asthma increased 2.1 X by antibiotics, Child milk allergy increased 4.4 X by PPI – April 2018
- Growth Hormone treatment raised vitamin D levels by 16 ng – 2018
- Major increases in childhood health problems
- Micronutrients (such as Vitamin D) for critically ill children – review Oct 2017
- Vitamin D guidelines of American Academy of Pediatrics said none should be even tested, yet 91 percent had less than 30 ng – June 2017
- Five times less mite allergy when vitamin D added in mid pregnancy and to infant – RCT April 2016
- Obese children – 71 percent had low vitamin D– Jan 2016
- Bone fractures in children requiring surgery were 55X more likely with low vitamin D – June 2015
- 3X more kids were vitamin D deficient when entering UK hospitals than 4 years before – Oct 2014
- Preschool children with low vitamin D visited their doctor more often – April 2014
- 5 out of 6 children who died in pediatric critical care unit had low vitamin D – May 2014
- Fewer pre-infants were vitamin D deficient when they got 800 IU – RCT Feb 2014
- The Vitamin Deficiency Signs That Can Send You to Prison – Feb 2014
- Severe tooth decay in children unless supplemented with Vitamin D drops – Oct 2013
- Presentation: pre and post natal vitamin D, with audience comments – Manchester UK Sept 2013
- 100,000 IU of vitamin D every 90 days was not frequent enough to prevent Diarrhea – Sept 2013
- Most European infants get vitamin D supplements, vs only 1 in 50 in US – June 2013
- Breastfed infants: 90 percent had less than 20 ng of vitamin D, formula-fed: 15 percent – May 2013
- Group is giving only 200 IU of Vitamin D to 70 million women and children to prevent Rickets
- Middle ear infection (Otitis Media) and Vitamin D – many studies
- Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT May 2013
- 75 percent of unexplained sudden infant deaths had inadequate level of vitamin D – April 2013
- Half of children with chronic illness had low levels of vitamin D – April 2013
- Symptoms of vitamin D deficiency vary with the age of the child – Feb 2013
- Vitamin D DRI for children lowered to 200 IU in Korea – Jan 2013
- Metabolic Syndrome in children is associated with low vitamin D – review Jan 2013
- UVB added in classroom reduced cavities, increased height, increased academics. etc
- Vitamin D Deficiency is a Strong Predictor (4X) of Asthma in Children – Oct 2012
- Early Puberty if low vitamin D - many studies
- Infants born early had low vitamin D levels – Oct 2012