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Both Vitamin D and Vitamin C fight cancers and aid anticancer drugs – May 2018

Insight into the roles of vitamins C and D against cancer: Myth or truth?

Cancer Lett. 2018 May 29;431:161-170. doi: 10.1016/j.canlet.2018.05.039. [Epub ahead of print]
Zhao CN1, Li Y1, Meng X1, Li S2, Liu Q1, Tang GY1, Gan RY3, Li HB4.


Dr. Grant

Cancer category in VitaminDWiki starts with the following

Cancers get less Vitamin D when there is a poor Vitamin D Receptor

The consumption of vitamins C and D for prevention and treatment of cancer is still an uncertain recommendation due to their controversial roles in cancer. The epidemiological studies document that vitamins C and D possess potential antineoplastic property. In addition, accumulating experimental studies strongly support their anticancer efficacy both in vitro and in vivo, although the mechanisms of action are not completely clear. Vitamin C at pharmacological concentration has cancer-selective cytotoxicity in several cancer cell lines. Moreover, the cognition of vitamin D has become "hormone D", which modulates a variety of molecular targets and signaling pathways, contributing to the inhibition of cancer. Furthermore, limited small-scale clinical trials favor their roles as the adjuncts of standard cancer therapies. On the other hand, opposite opinions also exist, and high-quality evidence are still lacking to ascertain the roles of vitamins C and D in cancer. In general, in light of the potential and promising anticancer values of vitamins C and D, it is essential to gain insight into their roles in cancer based on current epidemiological, experimental and clinical studies.

PMID: 29857128 DOI: 10.1016/j.canlet.2018.05.039

PDF is available free at Sci-Hub 10.1016/j.canlet.2018.05.039




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10055 Vit C.jpg admin 29 Jun, 2018 65.73 Kb 820
10054 Cancer Vit D.jpg admin 29 Jun, 2018 153.35 Kb 737
10053 aid anticancer drugs.jpg admin 29 Jun, 2018 76.25 Kb 814