A Review of the Evidence Supporting the Vitamin D-Cancer Prevention Hypothesis in 2017
Anticancer Research February 2018 vol. 38 no. 2 1121-1136
Update ofthe study on this page Breast, Prostate and Colon Cancers are still strongly associated with low Vitamin D – Grant Jan 2020
- Vitamin D and Cancer Mortality – review Jan 2013
- Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014
- Vitamin D and Prevention of Cancer — Is it ready for Prime Time – March 2011
- The Anti-cancer Actions of Vitamin D – Jan 2013
- Solar UVB reduces Cancer Risk – Grant, Jan 2013
- Ethical challenge – giving vitamin D to only half of Cancer (etc) patients – Jan 2017
- Cancer risk in older women reduced 32 percent by 2,000 IU of Vitamin D plus Calcium – 4 year RCT Oct 2016
- Obesity linked to 13 cancers, the linkage is probably vitamin D – Aug 2016
- If you were born after 1960 your risk of getting cancer is 1 in 2 if you do not get a lot of vitamin D
- 'Cancer Screening Has Never Saved Lives' (but Vitamin D supplementation does) - Jan 2016
- Vitamin D does not improve cancer survival much – when dose size, etc. is ignored – Oct 2015
- Both Vitamin D and Vitamin C fight cancers and aid anticancer drugs – May 2018
Cancer category starts with the following
- Cancer
209 items Overview Cancer and vitamin D - After Cancer Diagnosis
84 items - Bladder Cancer
24 items - Breast Cancer
221 items Overview Breast Cancer and Vitamin D - Colon Cancer
113 items Overview Cancer-Colon and vitamin D - Leukemia
16 items - Liver Cancer
13 items - Lung Cancer
48 items Overview Lung cancer and vitamin D - Lymphoma Cancer
22 items - Other Cancer
55 items - Ovarian Cancer
21 items - Pancreatic Cancer
54 items - Prostate Cancer
91 items Prostate Cancer and Vitamin D studies - Skin Cancer
109 items Overview Suntans melanoma and vitamin D - Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019
- Vitamin D Reduces Cancer Risk - Why Scientists Accept It but Physicians Do Not - Feb 2019
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017
- Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
- Pancreatic cancer 55 percent less likely if optimal vitamin D (vs low) – Nov 2017
- Melanoma 25 X more likely if low vitamin D – Feb 2018
- Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)– Aug 2018
Cancers get less Vitamin D when there is a poor Vitamin D Receptor
- Cancer and the Vitamin D Receptor, a primer – Sept 2017
- Cancer is leading cause of death - Vitamin D and Receptor activators help
- Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
- Cancer (general) and VDR
15 articles - Breast Cancer and VDR
15 articles - Colon Cancer and VDR
9 articles - Prostate Cancer and VDR
6 articles - Skin Cancer and VDR
9 articles - Note some Health problems, such as some Cancers, protect themselves by actively reducing Receptor activation
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WILLIAM B. GRANT⇑
Sunlight, Nutrition, and Health Research Center, San Francisco, CA, U.S.A.
Correspondence to: William B. Grant, Sunlight, Nutrition and Health Research Center, PO Box 641603, San Francisco, CA 94164-1603, U.S.A. Tel: +1 4154091980, e-mail: wbgrant at infionline.netThe vitamin D–cancer prevention hypothesis has been evaluated through several types of studies, including geographical ecological studies related to indices of solar ultraviolet-B (UVB) dose (the primary source of vitamin D for most people), observational studies related to UVB exposure or serum 25-hydroxyvitamin D [25(OH)D] concentrations, laboratory studies of mechanisms, and clinical trials. Each approach has strengths and limitations. Ecological studies indirectly measure vitamin D production and incorporate the assumption that vitamin D mediates the effect of UVB exposure. Findings from observational studies with long follow-up times are affected by changing 25(OH)D concentrations over time. Most clinical trials have been poorly designed and conducted, based largely on guidelines for pharmaceutical drugs rather than on nutrients. However, three clinical trials do support the hypothesis. In general, the totality of the evidence, as evaluated using Hill's criteria for causality in a biological system, supports the vitamin D–cancer prevention hypothesis.
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- After Cancer Diagnosis