Toggle Health Problems and D

UV, sunshine, and vitamin D (87 charts) - Holick March 2013

Sunlight and Vitamin D: A global perspective for health

Matthias Wacker, Michael F. Holick
Dermato-Ednorcrinology Vol5 #1

Vitamin D is the sunshine vitamin that has been produced on this earth for more than 500 million years. During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B radiation and is converted to previtamin D3 which in turn isomerizes into vitamin D3. Previtamin D3 and vitamin D3 also absorb UV B radiation and are converted into a variety of photoproducts some of which have unique biologic properties. Sun induced vitamin D synthesis is greatly influenced by season, time of day, latitude, altitude, air pollution, skin pigmentation, sunscreen use, passing through glass and plastic, and aging. Vitamin D is metabolized sequentially in the liver and kidneys into 25-hydroxyvitamin D which is a major circulating form and 1,25-dihydroxyvitamin D which is the biologically active form respectively. 1,25-dihydroxyvitamin D plays an important role in regulating calcium and phosphate metabolism for maintenance of metabolic functions and for skeletal health. Most cells and organs in the body have a vitamin D receptor and many cells and organs are able to produce 1,25-dihydroxyvitamin D. As a result 1,25-dihydroxyvitamin D influences a large number of biologic pathways which may help explain association studies relating vitamin D deficiency and living at higher latitudes with increased risk for many chronic diseases including autoimmune diseases, some cancers, cardiovascular disease, infectious disease, schizophrenia and type 2 diabetes. A three-part strategy of increasing food fortification programs with vitamin D, sensible sun exposure recommendations and encouraging ingestion of a vitamin D supplement when needed should be implemented to prevent global vitamin D deficiency and its negative health consequences.

PDF is not on VitaminDWiki

See also VitaminDWiki - recent Holick

Vitamin D update – Holick Sept 2013
Vitamin D, Sunlight and Cancer Connection – Holick Jan 2013
Dr. Holick video on vitamin D - March 2013
Vitamin D Global Perspective - Holick June 2013
Major review of Vitamin D – Holick Feb 2013
Go ahead, soak up some sun (but don’t burn) – Holick July 2015
Search VitaminDWiki with Holick in the title 36 pages as of March 2014

Here are a few of the charts

Image Image Image Image Image Image Image Image Image Image Image Image Image Image

Short url = http://is.gd/Holick32013

UV, sunshine, and vitamin D (87 charts) - Holick March 2013        
11701 visitors, last modified 05 Sep, 2015,
Printer Friendly PDF this page! Follow this page for updates

Attached files

ID Name Comment Uploaded Size Downloads
3259 F87.jpg admin 10 Nov, 2013 22:52 94.94 Kb 2240
3258 F83.jpg admin 10 Nov, 2013 22:52 65.44 Kb 2232
3256 F72.jpg admin 10 Nov, 2013 22:51 43.64 Kb 2243
3255 F68.jpg admin 10 Nov, 2013 22:51 93.92 Kb 4117
3253 F66.jpg admin 10 Nov, 2013 22:50 65.58 Kb 2371
3251 F59.jpg admin 10 Nov, 2013 22:49 47.53 Kb 1186
3250 F47.jpg admin 10 Nov, 2013 22:48 44.74 Kb 1353
3249 F42.jpg admin 10 Nov, 2013 22:48 112.03 Kb 4004
3248 F39.jpg admin 10 Nov, 2013 22:48 39.21 Kb 9158
3247 F38.jpg admin 10 Nov, 2013 22:47 59.81 Kb 2248
3246 F38.jpg admin 10 Nov, 2013 22:47 59.81 Kb 2419
3245 F32.jpg admin 10 Nov, 2013 22:47 37.97 Kb 2340
3244 F28.jpg admin 10 Nov, 2013 22:47 32.14 Kb 2402
3243 F27.jpg admin 10 Nov, 2013 22:46 34.31 Kb 2491
3242 F25.jpg admin 10 Nov, 2013 22:46 57.38 Kb 2493
See any problem with this page? Report it (FINALLY WORKS)