International Journal of Cancer, Article first published online: 29 NOV 2013. DOI: 10.1002/ijc.28603
Bruce K. Armstrong1,
Anne E. Cust1
1 Cancer Epidemiology and Services Research, Sydney School of Public Health, University of Sydney, NSW, Australia
2 Sydney School of Public Health, University of Sydney, NSW, Australia
† AMFS Investigators: Graham J. Mann, Joanne F. Aitken, Graham G. Giles, Richard F. Kefford, Bruce K. Armstrong, John L. Hopper, Helen Schmid, Elizabeth A. Holland, Mark A. Jenkins, Anne E. Cust.
‡ GEM Investigators: Marianne Berwick, Colin B. Begg, Irene Orlow, Bruce K. Armstrong Anne Kricker, Anne E. Cust, Alison Venn, Terence Dwyer, Richard P. Gallagher, Loraine D. Marrett, Elizabeth Theis, Lynn From, Roberto Zanetti, Stefano Rosso, Hoda Anton-Culver, Stephen B. Gruber, Homer Wilcox, Nancy E. Thomas, Timothy R. Rebbeck, Peter A. Kanetsky.
*Correspondence to: Kylie Vuong, Cancer Epidemiology and Services Research, QEII Building D02, The University of Sydney, NSW 2006, Tel.: +61-2-9036-3471, Fax: +61-2-9036-3480, E-mail: kylie.vuong at sydney.edu.au
Although sunburn and intermittent sun exposures are associated with increased melanoma risk, most studies have found null or inverse associations between occupational (more continuous pattern) sun exposure and melanoma risk. The association of melanoma with occupational sun exposure may differ according to anatomical site, with some studies finding a positive association with melanoma on the head and neck. We examined the association between occupational sun exposure (self-reported weekday sun exposure) and melanoma risk according to anatomical site, using data from two multicentre population-based case-control studies: the Australian Melanoma Family Study (588 cases, 472 controls) and the Genes, Environment and Melanoma study (GEM; 1079 cases, 2,181 controls). Unconditional logistic regression was used to estimate odds ratios (OR) and their 95% confidence intervals, adjusting for potential confounders.
Occupational sun exposure was not positively associated with melanoma risk overall or at different body sites in both studies.
The GEM study found inverse associations between occupational sun exposure and melanoma on the head and neck [OR for highest vs. lowest quartile: 0.56, 95% confidence intervals (CI) 0.36–0.86, ptrend 0.02], and between the proportion of total sun exposure occurring on weekdays and melanoma on the upper limbs (OR for highest vs. lowest quartile: 0.66, 95% CI 0.42–1.02, ptrend 0.03).
Our results suggest that occupational sun exposure does not increase risk of melanoma, even of melanomas situated on the head and neck. This finding seemed not to be due to negative confounding of occupational sun exposure by weekend sun.
My father worked outdoors, as a carpenter. He never got a sun burn nor had skin cancer.
I believe that, with most other things, skin cancer comes from getting too much of a good thing, all at once.
Examples which start with the letter S: sun, sugar, salt, salmon, sex, spinach, steak and smores
- On-job UV associated with LESS, not more, skin cancer - April 2013 similar conclusion to the study on this page
- Perhaps not burn from the sun if have enough vitamin D many hints that stocking up on vitamin D before going out in the sun helps.
- Sunlight, Vitamin D and Skin Cancer – 2nd edition Aug 2013
- Overview Suntan, melanoma and vitamin D
- UV, sunshine, and vitamin D (87 charts) - Holick March 2013
- Walking an hour a day (more vitamin D) decreased chance of breast cancer by 14 percent – Oct 2013
- Why do gardeners live longer (vitamin D, etc.)
- More Cancer, less Solar Radiation - 1941
- The Protective Role of Vitamin D Signaling in Non-Melanoma Skin Cancer - Nov 2013
- UV Radiation and the Skin June 2013 states that 5 sunburns doubles the risk of skin cancer
- Native American Indians mostly died of skin cancer (nope) not!
- Regular Occupational Sunlight Exposure is Associated with a Reduced risk of Melanoma on the Face and Arms Sunlight Institute Dec 2013
This is the way that VitaminDWiki became aware of the study on this page