There are about 500X more monthly visitors than newsletter subscribers.
Takes me ~8 hours to make a monthly newsletter.
In the time it takes to make a newsletter I can upload or improve about 30 web pages.
Each month in the past I have had to discard about 500 news items, as I did not have time to deal with them.
The majority of the past monthly newsletter items were descriptions of TOP NEWS
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The best items from past newsletters
Instant vitamin D test next year - consumables $4 or perhaps only $1 per test
Should provide an excellent vitamin D testing service in Dr. offices, pharmacies, etc.
Data on accuracies will be released after FDA approval, but the company could elect to start outside of the US
Which supplements I actually take not just vitamin D
Vitamin D intervention – 1204 clinical trials – May 2014
very very long list of diseases being considered to be prevented/treated by vitamin D
Some statistics for vitamin D intervention:802 trials for those 65+, 744 trials registered since Jan 2010, 135 health problems with 10 or more trials
3 X to 25 X more likely to have a health problem if low Vitamin D compiled by VitaminDWikiNew category DBP (Vitamin D Binding Protein) now has
Is too much vitamin D bad – possible causes and cures
#1 of 9 reasons: drug dosage often assumes low Vitamin D, High vitamin D increases/decreases dose potency
Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014
A rare meta-analysis which ignores the does levels which were very low or too far apart in time
Healthy in Seven Days- Success through vitamin D treatment – book 2014
Loading dose provides vitamin D benefit (50 ng) in just 7 days
He also has On-line questionare of symptoms to evaluate your Vitamin D deficiency
Question – I have a health problem associated with low vitamin D – should I take Vitamin D
Yes, even if low vitamin D was not the cause of your current problem it can be the cause for a future problem
10 reasons why seniors need more vitamin D than when they were young
VitaminDWiki chart updated April 2014 to include the latest intervention PROOFS
20 cent vitamin D pill similar to 2 hours sunbathing at 60 degree latitude – RCT Aug 2013
A 20 cent pill provides as much vitamin D as 2 hours of summer sun (during a sunny week)
If your time worth more than 10 cents an hour you should consider getting most of your vitamin D from a pill
Dieters lost 5 more pounds if achieved more than 32 ng of vitamin D – RCT March 2014
Finally, proof that getting enough vitamin D (>32 ng) will help you lose even more weight while on a diet
There had been lots of previous indications, but now we have proof via a Random Controlled Trial (which lasted a year)
(A few years ago 1/3 of the women in a study lost weight with vitamin D without any change in diet of exercise)
Levels of evidence for levels of vitamin D – Dec 2013
Concludes that there is good proof for: Premature mortality, Falls prevention, Cancer prevention,
Respiratory infection prevention, Diabetes prevention, Depression treatment, Musculoskeletal pain management
See also in VitaminDWiki Proof that Vitamin D Works Many reasons why vitamin D deficiency has become epidemic
Why India's vitamin D deficiency is grim - 40 pages Feb 2014
VitaminDWiki suggests home fortification for India: perhaps 20 cents for 4 man-months of vitamin D
By the way: all VitaminDWiki pages are now available in 80 languages (which includes 4 of the languages used in India)
Mice designed to get diabetes often failed to get diabetes if they had lots of vitamin D during their lives – Feb 2014
very similar to what has been seen in many Diabetes trial with humans
Rare diseases hit fewer than 1 in 1500 people, but 1 in 12 people have a rare disease (vitamin might D help)
VitaminDWiki has noticed many rare diseases which have benefited from Vitamin D, but has not had time to report on them
Vitamin D Deficiency: Time for Inaction (question mark)– Jan 2014 nice article by Dr. Plotnikoff
British Medical Journal 16 years ago published an editorial "Vitamin D Deficiency: Time for Action.".
Since then >20,000 Vitamin D papers have been published. but there has still been little action~
Fewer infants were vitamin D deficient when they got 800 IU – RCT Feb 2014
only 38% of infants who were getting 800 IU had <20 ng
The argument now seems to focus on the doses ranging between 1000 and 2000 IU for infants
Note: in the 1960's Finland gave 2,000 IU to infants, and no problem seen even 35 years later
unless you consider having far less diabetes being a problem
Many reasons why vitamin D deficiency has become epidemic lists 33 factors, 18 of which are recent
National requirement of vitamin D for pigs increased by 4X, (4X more than for humans) - Jan 2014
Yet again, the medical professsionals who get paid to keep their charges healthy (Vets) give 4X as much vitamin D
as do those for humans, who get income only when their charges are sick
Vitamin D sachets in India – fewer than a third had the stated amount – Nov 2013 very poor quality control in India. Apparently similar in Vietnam
Vitamin D at CureTogether: Fibromyalgia, MS, Psorasis, etc - Dec 2013
Lots of interesting charts showing what people actually take and what actually works
(Vitamin D is pretty good, somewhat surprising given the low doses which are bieng used so far)
Vitamin D Webinar - cost of pre-term birth etc- Baggerly Nov 2013
$51,000 cost of a pre-term birth OR about $80 of vitamin D (for 20 women): Could be a 400X Return On Investment to an HMO
Dr. Oz recommends at least 50 ng of vitamin D This is perhaps the 5th time Dr. Oz has recommended a 50 ng level
Incidence of 30 health problems related to vitamin D has doubled in a decade summary table with many supporting charts
Hypothesis – low vitamin D level may indicate Calcium deficiency – Masterjohn II Dec 2013 had not noticed that low Ca ==> low Vitamin D
Vitamin D repaired nerve in rat (50,000 IU daily dose equivalent for human) – June 2013 Perhaps vitamin D can aid spinal cord repair.
Is HyD (25(OH)D) a better form of vitamin D for some animals and maybe humans with liver problems
Available for animals now, but humans still now need a prescription – in the US anyway
Autism and Vitamin D - Dr. Cannell in Life Extension Mag - Jan 2014 includes text and graphics
Also has information on Dr. Cannell's previous work, including the 27 reasons to believe that Autism is connected to Vitamin D
If You're Low in This Nutrient, It Doubles Your Odds of Many Cancers– Interview Dr. Holick Oct 2013 Skype interview by Dr. Mercola
Vitamin D from 1940 and into the future – Holick video Nov 2013 Dr. Holick at Boston U., with lots of his great charts
Active Rheumatologic disease was 5X more likely with low vitamin D – June 2013
No proof yet that vitamin D will TREAT RA, but 5X is interesting
Different amounts of vitamin D needed to prevent different diseases – Dec 2013
Vitamin D is not a one-size-fits-all kind of solution, as many regulatory agencies would have us believe.
5,000 IU recommended by Vitamin D Council - Dec 2013
One of the reasons: 5,000 IU will get at least 97% of people above 30 ng/ml. WITHOUT TESTING
Death by Calcium, book by Thomas Levy – Dec 2013
Beware excessive Calcium, especially when taking lots of vitamin D
Typically takes a century for govts to fortify food with nutrients (like vitamin D)
And, even after a century, governments rarely provide enough fortification.
Solanum glaucophyllum (a purple flower) produces active vitamin D3
Hmm! Yet another natural source of a form of vitamin D. Should be of great interest to those with poor guts, livers. or kidneys
see also Getting Vitamin D into your body
Far too expensive to have FDA approve vitamin D – Dec 2013 A simple application costs $800,000
Hip fractures reduced 2X to 6X with just 10 minutes of sunlight daily – RCT 2003-2010
3 Delightful RCT from the the past 10 years. 3 RCT showing that a tiny amount of sunshine (and thus probably vitamin D) reduces hip fractures
WHO still says mistakenly says NO vitamin D during pregnancy, and only 200 IU after
Hmm: World Health Organization, based on a single random controlled trial which they labeled as being low quality, says that pregnant women should get NO vitamin D
Meanwhile, most researchers are arguing: should pregnant women get 4000 or 6000 IU of vitamin D
Only 1 in 3 in Scotland is vitamin D deficient ( less than 10 ng) - Nov 2013 If you set your standards low enough (10 ng), not many will be deficient
It appears that the standard should be 40 ng: but then >90% of the population on the planet would now be deficient.
But, it appears that just 100 years ago only a fraction of of people on the globe had <40 ng of vitamin D
20X increase in vitamin D sold and 36 percent decrease in osteoporosis business in Australia – Nov 2013
Wonder when they will realize that increasing D might indeed result in less osteoporosis
Note: There are now 117 items in Osteoporosis and Vitamin D in VitaminDWiki
More medical specialists are becoming aware of vitamin D
Bone 20X increase in vitamin D sold and 36 percent decrease in osteoporosis business in Australia – Nov 2013
Heart Vitamin D is not a cardiovascular fad like Vitamins C, E, Folic Acid, selenium, beta-caroteen, etc. – Circulation Nov 2013 their title, not ours
Gut Inflammatory bowel diseases are helped by vitamin D – commissioned review Nov 2013
Gut doctors appear to be not aware of other forms of vitamin D for poor guts nor that loading dose restore levels more quickly
From earlier this year: Why are doctors reluctant to accept vitamin D 10 reasons
Great Vitamin D webinar for doctors - Plotnikoff Nov 2013 You can read my many notes and perhaps then view his great video
Patent application for a skin cream which enhances production of vitamin D – Holick July 2013
If this becomes a product everyone will be able to make vitamin D at other than midday summer
Also, seniors will be able to make a lot more vitamin D than they can now.
Vitamin D important papers from 1645 to 2013 – Nov 2013 Science has known of the benefits of vitamin D for a long time. Wonder when the public will benefit
Actually, it has been much longer than 350 years: Sunny side of the hill is the healthiest – 400BC
Most European infants get vitamin D supplements, vs only 1 in 50 in US – June 2013
Why so little supplementation for US infants?
Perhaps because the US supplements milk and formula with a little bit of vitamin D and Americans think they are getting enough?
Is this a reason for vitamin D deficiency?
UV, sunshine, and vitamin D (87 charts) - Holick March 2013 here are a few of the charts
Elderly get less benefit from single dose of UVB than youth
Elderly can benefit from added indoor UVB
Blood pressure varies with latitude (UVB)
Vitamin D update – Holick Sept 2013 highlights by VitaminDWiki
Describes how vitamin D does it's magic for a wide variety of diseases - at the molecular level
Reviews results of many studies - including some published in the first half of 2013
Ideal level 40-60 ng/ml - maintenance dose 50,000 IU every two weeks
Loading dose 50,000 IU weekly
Calcium increase 2X to 3X with lots of vitamin D (> 40 ng?)
A few Vitamin D Overviews summaries which includes
37 proofs, Likelihood of health problems 2x-25X more with low vitamin D
Get disease X then likely to get disease Y – where both X and Y are associated with low vitamin D
Overview Pregnancy, Overview Cofactors, Overview Sports, Overview Alzheimers-Cognition, MS cures with 150 ng of vitamin D
How often to take 50,000 IU of vitamin D (based on double-blind intervention proofs)
Vitamin D Webinars by DiaSorin 2013-2014 some interesting webinars, such as
The Shocking Truth About Vitamin D Status
Vitamin D: Optimizing Pain Management
Updated the section on Optimum level of vitamin D – how has 37 supporting items
Optimum/Optimal is being used with Vitamin D more frequently in PubMed papers
Vitamin D podcast with VitaminDWiki - Oct 2013 Voice and transcript.
Wide discussion of vitamin D concerns with some emphasis on sports.
Hypothesis: Magnesium accounts for some of the variation in vitamin D response – Oct 2013 one of several recent articles of synergism of Mg and Vitamin D
Diabetes prevention RCT kicked off: adding 4,000 IU vitamin D - Oct 2013 Prediction: Will fail due to not finding enough suckers willing to limit their vitamin D to only 600 IU
Type 1 diabetes starting to decrease in Finland, they started Vitamin D fortification in 2003 – July 2013
they are just starting to study other health changes. Should be interesting
Cooking reduces vitamin D content by about 30 percent – Oct 2013 Nice to find.
You can add vitamin D as home to foods which will be cooked, in addition to adding it to sugar, salt, jams, etc,
Gestational Diabetes mostly treated with just 2 doses of 50,000 IU of vitamin D – RCT Dec 2013 the 33rd disease that Vitamin D is proven to prevent/treat
Vitamin D intervention for 8 weeks of pregnancy: infants taller, heavier and bigger heads – RCT Oct 2013 the 32nd disease that Vitamin D is proven to prevent/treat
Antibiotic use cut in half by elderly (over 70) after monthly 60,000 IU of vitamin D – RCT Dec 2013 the 31st disease that Vitamin D is proven to prevent/treat
Muscle increased 17 percent in vitamin D insufficient elderly getting 4,000 IU for 4 months – RCT Oct 2013 the 30th disease that Vitamin D is proven to prevent/treat
World Osteoporosis Day sponsored by Big Pharma – does not give good sun or vitamin D info Oct 20 2013
5 of the 6 sponsors are big pharmaceutical firms, which have no interest in the no-profit vitamin D
Any supplementation with vitamin D reduced chance of pneumonia by 50 percent – Oct 2013
The analysis most likely would have found more reduction in pneumonia if they had looked at just high doses – say >2,000 IU
Hypothesis: Colorado has the best UV (and thus best health) in the US
First noticed that they had lowest obesity in the US.
“Best” UV because they do not also have the high temperatures which cause people to go indoors.
One of the maps: Diabetes Deaths
Vitamin D deficiency diseases in dark skinned people living far from equator – Meta-analysis Oct 2013
As we have seen in many previous studies, dark skin = 24 hour a day sunscreen, which is not good for health when there is not a hot sun.
Yet again, 800 IU of vitamin D was found to be barely enough to help bones – Lancet Oct 2013
Amazingly this study resulted in 40 different article titles saying that this proves that vitamin D does not help bones
AND, an additional 13 articles claimed that Vitamin D has not benefit at all (based on this single Osteoporosis publication)
By the way – many studies have shown that 2000+ IU of vitamin D is needed to reduce the chance of osteoporosis
One test to estimate Vitamin D, A, Cu, Se, etc : measure proteins in blood – Oct 2013 measures many blood proteins which are proxies for vitamins and minerals
Vitamin D podcast with VitaminDWiki - Oct 2013 some emphasis on recreational running, exercise, not professional
– – – – OPTIMUM LEVEL – – – – – A new category at VitaminDWiki – – – –
Sleep disorders cured by 60-80 ng of vitamin D and some B vitamins – March 2013
Optimum Vitamin D level: Evidence for 30 and 40 ng – Grant Aug 2013
Vitamin D provides many benefits and is cost-effective (need 32-40 ng) – Summer 2013
Restoring vitamin D - ways to encourage Ways to encourage people to restore to optimum levels, like those of their great grandparents
Update on Treating Multiple Sclerosis with high dose vitamin D - Sept 2013 appears that the goal is 150 ng
Multiple Sclerosis prevention by Vitamin D: 10 year, 30 million dollar trial - Sept 2013 wish that this trial were using a higher dose level
Restless legs and growing pains may be both due to low vitamin D – Sept 2013
EVERY restless leg symptom is also a symptom of growing pains.
There are several references to both health problems being associated with low vitamin D.
– – – – – FORTIFICATION – – – – – –
Type 1 diabetes starting to decrease in Finland, they started Vitamin D fortification in 2003 – July 2013 Fortification appears to help
Danish study of childhood diseases vs vitamin D fortification – May 2013 should publish some interesting results in 2014
Fewer heart attacks, hip fractures and deaths if more skin cancer – Sept 2013
This study has a great way to estimate the benefits of vitamin D back before there were vitamin D tests.
20 ng is enough vitamin D for healthy Nordic Caucasians: 5th Nordic meta-analysis – Oct 2013
2/3 of the proofs that Vitamin D intervention works had been published when the Nordic study stopped looking
– – – – – – COFACTORS – – – – – – – -
If at high risk of vitamin D deficiency, get a higher response if take more Magnesium – Sept 2013
Supports previous idea that having enough Magnesium would increase response to a dose of vitamin D by about 30%
Synergism between Vitamin D, Vitamin K-2, and Vitamin A: Masterjohn – Sept 2013 Masterjohn always has excellent insight in vitamin D and its cofactors
Handbook of Vitamin D in Human Health – June 2013 Large technical book – you might find the book for free on the web
Presentation: pre and post natal vitamin D, with audience comments – Manchester UK Sept 2013 Excellent ideas about vitamin D information-sharing and education
Cluster headaches substantially reduced by 10,000 IU of Vitamin D in 80 percent of people I had an excellent conversation with the person.
Both Vitamin D and Calcium are needed to reduce bone loss – RCT Sept 2013 Need BOTH.
So many reports of this study (incorrectly) stated that vitamin D does not help with osteoporosis.
3 to 55 X more likely to have these health problems if low Vitamin D Summary of Vitamin D data at VitaminDWiki sorted by biggest possible benefit.
Life extension and health improvement: Calico (Google) and perhaps Vitamin D
Google is interested in life extension and improved health– perhaps we should point out the benefits of vitamin D to both
– – – – – – CANCER – – – – – – – –
Far fewer Pancreatic Cancer deaths at stage III and IV with more than 20 ng vitamin D – Sept 2013
This is not proof that increasing vitamin D reduces Pancreatic Cancer, but it is a good indication
Molecular Link between Vitamin D and Cancer Prevention – Oct 2013 further proof as to how Vitamin prevents Cancer
Walking an hour a day (more vitamin D) decreased chance of breast cancer by 14 percent – Oct 2013
Probably just $5 a year of vitamin D supplements would get the same level of benefit
Benefits of supplements (vitamin D is not snake oil) - Aug 2013
Proof via PubMed for various supplements, including vitamin D. Nice update from 2010 and 2011
Obese need 2.5 IU of vitamin D per kg to increase 1 ng (about 3.4 X more) – RCT Sept 2013
Those who are 2X heavier need 3.4X more I.U. of vitamin D – (supposed dilution effect would be only 2X)
Superbug (Clostridium difficile) 4.7X more of a problem if low vitamin D – Sept 2013
Yet another hospital acquired infection is treated with vitamin D
Far fewer Pancreatic Cancer deaths at stage III and IV with more than 20 ng vitamin D – Sept 2013
Another study showing that vitamin D might treat Pancreatic Cancer
Vitamin D reduced bacterial infection in cows – RCT Sept 2013
Animal doctors appear to be learning about vitamin D faster than doctors for humans. (But vets have an incentive - they are paid to keep their clients healthy)
2X increased chance of anemia (low iron) associated with low vitamin D – Sept 2013
This adds to the previous 5 or so articles on Iron and Vitamin D
Interactions of Vitamins D, A, and K, should measure calcitriol, calcification – Masterjohn Aug 2013
Masterjohn continues to have extremely interesting ideas. The title includes a few of the topics of an audio recording
100,000 IU of vitamin D every 90 days was not frequent enough to prevent Diarrhea – Sept 2013
When will researchers learn that infrequent doses of vitamin D (quarterly, semi-annual, annual) provide less benefit and actually can harm?
Suncation adds 12 ng of vitamin D to Sweden women – Sept 2013
$20 of vitamin D provide a year's worth of vitamin D. An expensive annual trip to a sunny climate provides only a few months worth of vitamin D.
Why do gardeners live longer (vitamin D, etc.)
Note also: Most elderly in cultures with the most longevity have gardens
30 to 50 ng of vitamin D is optimal – Central Europe consensus Sept 2013
Vitamin D provides many benefits and is cost-effective (need 32-40 ng) – Summer 2013
FYI: 40 ng is the minimum optimal vitamin D level being proposed in our upcoming video
Even if a J curve exists, it is 50X better to give vitamin D than not give it – May 2013
This editorial nicely puts the worry about possible problems with high levels of vitamin D into perspective.
Recommended increasing vitamin D for space flight – NASA Sept 2013
NASA scientists keep re-discovering that vitamin D is needed in space flight, yet NASA procedures have not changed.
Incidence of 30 health problems related to vitamin D has doubled in a decade about 18 charts showing increased incidence of disease -typically by at least 3X
all of which appear to be associated with increased # of people who are vitamin D deficient
Diabetes, Obesity, Cancer - Thyroid, Cancer - Childhood, Cancer - Breast, Cancer - Melanoma, B, TB and HIV in Africa, Multiple Sclerosis, Autism,
Ulcerative Colitis and Crohn's Disease, Concussions, Traumatic Brain Injury - military, Parkinson Diseas,|Pulmonary Hypertension
|Multiple Sclerosis||Autism||Ulcerative Colitis and Crohn's Disease||Crohn's Disease|
Diabetics with low vitamin D had more cognitive impairment– Aug 2013 Should this be called Diabeticbrain, similar to Chemobrain?
Huge variation in taking vitamin D supplements with age of female, less than 1000 IU not help much – July 2013 5X variation in % of females taking vitamin D vs age
45 ng vitamin D may be enough (what about vitamin A)- Aug 2013 Another study showing possible problem with high levels of vitamin D.
Wonder if too much vitamin A or too little Mg or vitamin K-2
11,000 IU vitamin D daily from traditional Norwegian diet of cod, cod liver, cod-liver oil, and roe – 2004 People used to get enough vitamin D from foods in the winter.
also used to get it from "Free Range Lard", liver, eel, pies and other baked goods, pemican (which was 50% lard/tallow - and may have had > 10,000 IU per pound)
Breed cows based on vitamin D production – Aug 2013 Some "free range cows" in sunny climates give 750 IU of vitamin D per liter of milk
To be reimbursed for supplements in the UK the benefits must now be approved by EU – Aug 2013 UK govt clamping down on supplements
Half of elderly care physicians in the Netherlands do not follow vitamin D guidelines – 2013 Many doctors still not following even the minimal vitamin D guidelines
Repurposed the recent Grassroots data into the following chart
11,000 IU vitamin D daily from traditional Norwegian diet of cod, cod liver, cod-liver oil, and roe – 2004 occasionally during the winter.
Air conditioning has not totally canceled the latitude effective in the US yet – July 2013 it still persists. Not nearly as strong as 50 years ago.
Diabetes 10X less frequent among people getting lots of vitamin D - Aug 2013 another great chart from Grassroots Health