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Multiple Sclerosis half as likely if get plenty of sunshine (not a news item) – March 2018

Sun exposure over the life course and associations with multiple sclerosis

March 7, 2018, DOI: https://doi.org/10.1212/WNL.0000000000005257
Helen Tremlett, Feng Zhu, Alberto Ascherio and Kassandra L. Munger


Studies in both Mutliple Sclerosis and UV are listed here:

Note: About a 10X difference of MS with latitude BEFORE air conditioning

 Download the PDF from VitaminDWiki
Chart of data by Grassroots Health

Objective To examine sun exposure and multiple sclerosis (MS) over the life course (ages 5–15 and 16–20 years, every 10 years thereafter).

Methods Cases with MS (n = 151) and age-matched controls (n = 235) from the Nurses' Health Study cohorts completed summer, winter, and lifetime sun exposure history questionnaires. Cumulative ambient ultraviolet (UV)-B (based on latitude, altitude, cloud cover) exposure before MS onset was expressed as tertiles. Seasonal sun exposure was defined as low vs high hours per week (summer [≤9 vs >10 h/wk]; winter [≤3 vs >4 h/wk]). Relative risks (RRs) and 95% confidence intervals (CIs) were estimated via conditional logistic regression with adjustment for body mass index, ancestry, smoking, and vitamin D supplementation.

Results Most participants were white (98%); the mean age at MS onset was 39.5 years. Living in high (vs low) UV-B areas before MS onset was associated with a 45% lower MS risk (adjusted RR 0.55, 95% CI 0.42–0.73).
Similar reduced risks (51%–52%) for medium or high exposure were observed at ages 5 to 15 years and at 5 to 15 years before MS onset (adjusted p < 0.05).
At age 5 to 15 years, living in a high (vs low) UV-B area and having high (vs low) summer sun exposure were associated with a lower MS risk (RR 0.45, 95% CI 0.21–0.96).

Conclusion Living in high ambient UV-B areas during childhood and the years leading up to MS onset was associated with a lower MS risk. High summer sun exposure in high ambient UV-B areas was also associated with a reduced risk.

Created by admin. Last Modification: Thursday May 9, 2019 11:16:22 GMT-0000 by admin. (Version 8)

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11921 MS UV 2018.jpg admin 09 May, 2019 75.99 Kb 419
11920 NEUROLOGY2017839183.pdf admin 09 May, 2019 528.81 Kb 465