300,000 IU of Vitamin D - many studies

50+ VitaminDWiki pages have 300,000 in the title
At least 18+ VitaminDWiki injection pages have 300,000 in the title
VitaminDWiki – Injection - few reasons to have this expensive form with slow response
VitaminDwiki – Comparing High-dose vitamin D therapies contains:
VitaminDwiki – High-Dose contains:

50+ VitaminDWiki pages have 300,000 in the title

The list is automatically updated

Items found: 50

Title		Modified
300,000 IU of Vitamin D - many studies		26 Oct, 2024
TBI reduced 5X by 300,000 IU of vitamin D (injection) – RCT Oct 2024		25 Oct, 2024
Menstrual pain reduced by Vitamin D (50,000 weekly or 300,000 monthly) – meta-analyses		11 Apr, 2024
Breastfeeding Vitamin D loading dose of 300,000 IU is OK - UK govt. Dec 2023		04 Jan, 2024
Thin Choroid (eye lining) in children thickened by 300,000 IU of Vitamin D – July 2023		03 Jul, 2023
Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT Jan 2021		24 Feb, 2023
Less likely to die of various causes if higher Vitamin D (data from 300,000 people) – Oct 2022		25 Oct, 2022
Surgeries often deplete Vitamin D - 300,000 IU resulted in little response – Nov 2018		02 Aug, 2022
Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017		04 Jul, 2022
Vitamin D restored in teens by doses totalling 300,000 IU – Nov 2014		29 Oct, 2021
COVID-19 patients getting 300,000 IU of Vitamin D were 5X less likely to die – Sept 2021		28 Sep, 2021
ICU Vitamin D injection (300,000 IU) helped - RCT Feb 2021		21 Aug, 2021
Fewer days in hospital if 300,000 IU of vitamin D before brain surgery - RCT Feb 2021		25 Jan, 2021
Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT Dec 2020		07 Jan, 2021
Fewer days in ICU after 300,000 IU of vitamin D, but not 540,000 – meta-analysis Aug 2020		02 Sep, 2020
Vitamin D reduced depression – single 300,000 IU – RCT Aug 2020		22 Aug, 2020
A single dose of 300,000 IU of vitamin D should fight COVID-19 for 2 months - Hypothesis - Aug 21, 2020		21 Aug, 2020
Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT Feb 2020		25 Jul, 2020
300,000 IU injection loading dose of vitamin D3 stopped gestational diabetes in RCT – Oct 2011		25 Jul, 2020
10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT March 2019		18 Jul, 2020
COVID-19 might be fought by 2 doses of Vitamin D (200,000-300,000 IU each) – Feb 2020		23 Mar, 2020
300,000 IU of Vitamin D is not enough during pregnancy – RCT May 2018		25 Jun, 2019
Sexual disfunction treated by 300,000 IU of Vitamin D – RCT Nov 2018		02 Jan, 2019
Esophageal Cancer surgery helped by 300,000 IU of Vitamin D – RCT Sept 2018		18 Sep, 2018
Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT Aug 2018		16 Aug, 2018
Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018		29 Jun, 2018
Sickle Cell clinical trial will inject 300,000 IU of vitamin D – RCT due 2020		31 Jan, 2018
Vitamin D injection of 300,000 IU helped a bit, but many had a very small response – Dec 2017		19 Jan, 2018
Brain Tumor surgery – will previous injection of 300,000 IU Vitamin D help – RCT 2018		29 Dec, 2017
Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017		06 Dec, 2017
Early Rheumatoid Arthritis helped by 300,000 IU of vitamin D – RCT June 2017		23 Sep, 2017
300,000 IU Vitamin D injection before brain tumor surgery – RCT to finish Dec 2017		20 Aug, 2017
Rheumatoid Arthritis nicely treated by Vitamin D (300,000 IU loading dose) – May 2017		24 Jul, 2017
Ulcerative colitis treated by injection of 300,000 IU of vitamin D – RCT July 2016		29 Apr, 2017
Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015		05 Apr, 2017
Diabetes (Type II) reduced by single injection of 300,000 IU of vitamin D3 – RCT March 2014		12 Mar, 2017
300,000 IU loading dose of vitamin D does not help the obese much – Jan 2017		01 Feb, 2017
300,000 IU of vitamin D injection not enough to statistically reduce markers of Venous Thromboembolism – RCT July 2016		28 Jan, 2017
Critically ill injected with 300,000 IU of vitamin D, 3X more likely to die if PTH did not respond - RCT July 2015		22 Jan, 2017
Single 300,000 IU Vitamin D dose lasts about 2 months– Nov 2016		03 Nov, 2016
Loading dose of 300,000 IU of vitamin D does not last long – March 2014		03 Nov, 2016
Large single dose of more than 300,000 IU of vitamin D works well for 3 months – Review Nov 2013		07 Aug, 2016
Reduced depression with single 300,000 IU injection of vitamin D – RCT June 2013		22 May, 2015
Rheumatology patients in Switzerland getting more vitamin D recently (300,000 IU) – Dec 2013		12 Jun, 2014
Vitamin D for Italians – Senior 2300 IU, if deficient loading dose of at least 300,000 IU– Med Society 2011		19 Mar, 2014
Injection of 300,000 IU of vitamin D3 similar to 10 months of oral 25,000 IU – Jan 2014		29 Jan, 2014
300,000 IU every 3 months helped raise vitamin D levels in half of RA patients – April 2012		14 Dec, 2013
300,000 IU of vitamin D2 reduced inflammation markers (cytokines and chemokines) – Sept 2013		09 Sep, 2013
Loading dose of 300,000 IU vitamin D every 6 months – Dec 2011		31 Aug, 2012
300,000 IU vitamin D helped seniors in many ways – May 2011		16 May, 2011

At least 18+ VitaminDWiki injection pages have 300,000 in the title

The list is automatically updated

Items found: 18

Title		Modified
TBI reduced 5X by 300,000 IU of vitamin D (injection) – RCT Oct 2024		25 Oct, 2024
ICU Vitamin D injection (300,000 IU) helped - RCT Feb 2021		21 Aug, 2021
Fewer days in hospital if 300,000 IU of vitamin D before brain surgery - RCT Feb 2021		25 Jan, 2021
Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT Dec 2020		07 Jan, 2021
Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT Feb 2020		25 Jul, 2020
300,000 IU injection loading dose of vitamin D3 stopped gestational diabetes in RCT – Oct 2011		25 Jul, 2020
10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT March 2019		18 Jul, 2020
Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT Aug 2018		16 Aug, 2018
Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018		29 Jun, 2018
Sickle Cell clinical trial will inject 300,000 IU of vitamin D – RCT due 2020		31 Jan, 2018
Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017		06 Dec, 2017
300,000 IU Vitamin D injection before brain tumor surgery – RCT to finish Dec 2017		20 Aug, 2017
Ulcerative colitis treated by injection of 300,000 IU of vitamin D – RCT July 2016		29 Apr, 2017
Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015		05 Apr, 2017
Diabetes (Type II) reduced by single injection of 300,000 IU of vitamin D3 – RCT March 2014		12 Mar, 2017
300,000 IU of vitamin D injection not enough to statistically reduce markers of Venous Thromboembolism – RCT July 2016		28 Jan, 2017
Reduced depression with single 300,000 IU injection of vitamin D – RCT June 2013		22 May, 2015
Injection of 300,000 IU of vitamin D3 similar to 10 months of oral 25,000 IU – Jan 2014		29 Jan, 2014

VitaminDWiki – Injection - few reasons to have this expensive form with slow response

64 items in Vitamin D Injection category

Vitamin D injections last longer (3 month vs 2 month) than loading doses
Getting Vitamin D into your body shows the many ways of getting Vitamin D

Injections are currently made by medical professionals into muscle
Home injection of Vitamin D appears to be possible in the future
Injections are useful for people who might forget to take their periodic supplement (children, elderly, etc) and those who cannot swallow or have poor digestion
While Vitamin D2 is historically the common form, Vitamin D3 is far better
Should check (if there is time) for possible allergic reaction to Vitamin D or lack of Magnesium for both for loading dose and injection
Note 600,000 IU Vitamin D loading dose via capsules is 1/20th the cost($2.40) of an injection, and does not require a prescription
100,000 IU single dose of vitamin D - 2010 has the following
Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017 has the following
Non-oral Vitamin D should be a better form for MS, food allergy, PTSD, etc. – many studies might include injection

VitaminDwiki – Comparing High-dose vitamin D therapies contains:

	Dr. Coimbra books 2018 2016	Dr. Somerville Optimal Dose	Dr. Gominak	Mr. Batcheller	Dr. Bredsen End of Alz.
Health problem	Multiple Sclerosis autoimmune, PD	sleep, flu, pain, obesity, etc.	Sleep	Cluster, Migraine Headaches	Alzheimer's Park. being added
Number of people (2019)	30,000 by 2022	5,000	5,000	8,000 (2023)	>1,000 ?
Vitamin D target	PTH is target typ: 150ng of D	100-140+ ng	60-80 ng	PTH is target typ: 80 ng of D	40-60 ng
Vitamin D daily dose (K = 1,000 IU)	20K - 200K 1,000 IU/kg	30K	2K + monthly test increasing dose until goal	4K - 40K 110 IU/kg	?
Omega-3 *	O-3	O-3	- - -	O-3	O-3
Magnesium *	Mg	Mg	- - -	Mg (400 mg)	-
Vitamin K2	K2 (no longer?)	K2	- - -	K2	-
Vitamin B...	B2, B9, B12	B3	B50-B100 3 months	B50	B12
Zinc *	Zn		- - -	Zn	-
Boron *?	B		- - -	B	-
Calcium Minimize rock-based Ca	Decrease Ca		- - -	Ca	-
Vitamin A avoid extremes	avoid A	avoid A	- - -	A	-
Other	Choline Selenium Co-Q 10		- - -	Co-Q 10	-
Loading dose Days instead of months	- - -	- - -	- - -	Loading "Cluster Balm"	-

VitaminDwiki – High-Dose contains:

High Dose = the on-going use of >5,000 IU (daily average)
Dosing frequency: 1 per day to 1 per 17 days is best, however some studies use monthly dosing
High Dose has been used millions of times - safely and effectively
High Dose for more than 6 months should include the adjustment of co-factors
>100,000 daily can be toxic in 3 weeks if cofactors are not adjusted
Can be via injections
High dose is not the same as a Loading Dose (bolus)
- A Loading Dose is a high-dose typically completed in less than 30 days
See also
Is 50 ng of vitamin D too high, just right, or not enough
Vitamin D: Bolus is Bogus (if more than 17 days between oral doses) – Oct 2021

High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis April 2022

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