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Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015

Vitamin D replacement therapy in patients with cardiac syndrome X

Perfusion January 2015 vol. 30 no. 1 60-63
A Andishmand, Z Ansari, MH Soltani, H Mirshamsi mirshamsih at yahoo.com, S Raafat
Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Hamide Mirshamsi Cardiovascular Department Afshar Hospital, Jomhoori Blvd Yazd, 8917945556 Iran.

Aims: The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.

Methods: Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.

Results: At the end of the treatment course (75±6 day),

  • a significant increase of serum vitamin D3 occurred and was within the normal range (45±8 ng/ml) and
  • the frequency of angina improved significantly (p=0.003).
  • Exercise duration and maximal work capacity increased significantly (p<0.001).
  • Maximal ST-segment depression (mm) decreased significantly (p=0.001).
  • The calculated Duck treadmill score improved significantly (p=0.001).

Conclusions: Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.
 Download the PDF from VitaminDWiki

It appears that the main benefit of injection is that the doctor get more income and does not have to worry about compliance
secondary reason for using injection - poor digestion
300,000 IU averaged over 14 days could be as well accomplished by other means
Example: 50,000 IU of vitamin D every 2nd day

See also VitaminDWiki

Injection contains

61 items in Vitamin D Injection category


  • Injections are currently made by medical professionals into muscle
  • Home injection of Vitamin D appears to be possible in the future
  • Injections are useful for people who might forget to take their periodic supplement (children, elderly, etc) and those who cannot swallow or have poor digestion
  • While Vitamin D2 is historically the common form, Vitamin D3 is far better
  • Should check (if there is time) for possible allergic reaction to Vitamin D or lack of Magnesium for both for loading dose and injection
  • Note 600,000 IU Vitamin D loading dose via capsules is 1/20th the cost($2.40) of an injection, and does not require a prescription
  • 100,000 IU single dose of vitamin D - 2010 has the following
  • Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017 has the following

VitaminDWiki Cardiovascular pages with "Cardiac syndrome X" in title (3 as of Nov 2022)

This list is automatically updated

Items found: 3

See also web

Attached files

ID Name Comment Uploaded Size Downloads
7891 cardiac syndrome X.pdf PDF 2015 admin 05 Apr, 2017 18:17 333.98 Kb 676
7276 Angina reduced.pdf PDF 2016 admin 02 Nov, 2016 14:43 91.09 Kb 901