Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015

Vitamin D replacement therapy in patients with cardiac syndrome X

Perfusion January 2015 vol. 30 no. 1 60-63
A Andishmand, Z Ansari, MH Soltani, H Mirshamsi mirshamsih at yahoo.com, S Raafat
Cardiovascular Research Center, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Hamide Mirshamsi Cardiovascular Department Afshar Hospital, Jomhoori Blvd Yazd, 8917945556 Iran.

Aims: The aim of present study was to assess whether vitamin D, with proven beneficial effects on the cardiovascular system, has any effect on angina and exercise-induced ischemia in patients with cardiac syndrome X and low serum vitamin D.

Methods: Patients with cardiac syndrome X and low serum vitamin D3 were studied before and after treatment with an intramuscular injection of vitamin D3 (300,000 units, every other week for 2 months). We determined the angina episode (per day) and several indices of exercise capacity.

Results: At the end of the treatment course (75±6 day),

• a significant increase of serum vitamin D3 occurred and was within the normal range (45±8 ng/ml) and
• the frequency of angina improved significantly (p=0.003).
• Exercise duration and maximal work capacity increased significantly (p<0.001).
• Maximal ST-segment depression (mm) decreased significantly (p=0.001).
• The calculated Duck treadmill score improved significantly (p=0.001).

Conclusions: Our findings show that vitamin D replacement therapy in patients with cardiac syndrome X and vitamin D deficiency dramatically improves symptoms and signs of ischemia.
 Download the PDF from VitaminDWiki

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It appears that the main benefit of injection is that the doctor get more income and does not have to worry about compliance
secondary reason for using injection - poor digestion
300,000 IU averaged over 14 days could be as well accomplished by other means
Example: 50,000 IU of vitamin D every 2nd day

See also VitaminDWiki

• Overview Cardiovascular and vitamin D
• Search vitaminDWiki for ANGINA 286 items as of Nov 2022
• Review of Vitamin D (including free, frequency, injection, how much.) – Sept 2013
• Vitamin D supplementation protocols: loading, injection, etc – RCT June 2014
• Overview Pain and Vitamin D

Injection contains

65 items in Vitamin D Injection category

• Vitamin D injections last longer (3 month vs 2 month) than loading doses
• Getting Vitamin D into your body shows the many ways of getting Vitamin D

• Injections are currently made by medical professionals into muscle
• Home injection of Vitamin D appears to be possible in the future
• Injections are useful for people who might forget to take their periodic supplement (children, elderly, etc) and those who cannot swallow or have poor digestion
• While Vitamin D2 is historically the common form, Vitamin D3 is far better
• Should check (if there is time) for possible allergic reaction to Vitamin D or lack of Magnesium for both for loading dose and injection
• Note 600,000 IU Vitamin D loading dose via capsules is 1/20th the cost($2.40) of an injection, and does not require a prescription
• 100,000 IU single dose of vitamin D - 2010 has the following
  
• Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017 has the following
  
• Non-oral Vitamin D should be a better form for MS, food allergy, PTSD, etc. – many studies might include injection

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VitaminDWiki Cardiovascular pages with "Cardiac syndrome X" in title (3 as of Nov 2022)

This list is automatically updated

See also web

• Effect of Vitamin D on Anginal Episodes in Vitamin D Deficient Patients with Chronic Stable Angina on Medical Management Aug 2016
  60,000 IU weekly for 8 weeks ==> 20% reduction in # of episodes
   Download the PDF from VitaminDWiki