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Headaches decreased by Vitamin D, Magnesium etc. – Review March 2022

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Curr Pain Headache Rep . 2022 Mar 7. doi: 10.1007/s11916-022-01019-9.PDF behind paywall
Shadi Ariyanfar # 1, Soodeh Razeghi Jahromi # 2, Mansoureh Togha 3, Zeinab Ghorbani 4

Purpose of review: The lifetime prevalence of headaches is 96%. Approximately 11% of the adult population worldwide has a migraine headache. Migraine is a complex disorder that is more than a simple headache. So far, many underlying mechanisms, i.e. inflammatory, vascular, neurogenic have been hypothesized. In recent years evidences proposed that an energy deficit due to changes in mitochondrial function contributes to migraine pathophysiology as an upstream disorder. Recent insights suggested that the coexistence of sensory-stimuli surplus and energy-reserve shortage activate the trigeminovascular system. Some nutrients are considered as essential elements in mitochondrial bioenergetics and some others are known as natural immuno-modulatory components. Also, evidence showed their beneficial effect in headache prophylaxis and treatment. In present study, we aimed to review the available data in this field.

Recent findings: Vitamin B group, magnesium, and Coenzyme Q10 (CoQ10) are well-known for their function in mitochondrial energy metabolism. On the other hand, studies support their beneficial role in controlling migraine headache symptoms. For instance, daily intake of 400-milligram riboflavin for 3 months resulted in more than 50% reduction in migraine attacks in more than half of the consumers.
According to recent evidence, vitamin D and Omega-3 which are considered as famous immune-modulatory compounds are also reported to be effective in migraine prophylaxis. For example, every 22% reduction in migraine headache occurrence was reported for every 5 ng/ml rise in serum vitamin D. Supplementation with vitamin B group, CoQ10, magnesium, vitamin D and Omega-3 could be considered as an effective, less costly strategy in headache/migraine prophylaxis.


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VitaminDWiki - Headache starts with

48 Headache pages

Cluster Headache, etc.

21+ VitaminDWiki pages have MIGRAINE in the title
This list is automatically updated

Items found: 22
Title Modified
Migraine Headache duration and intensity reduced by 50,000 IU vitamin D every two week plus probiotics – RCT Oct 2024 14 Oct, 2024
Cluster and Migraine headache treatment protocol - Sept 2023 29 Sep, 2023
Migraine and Vitamin D 16 Jul, 2023
Migraine risk reduced 30% if have lots of Zinc - Jan 2023 18 Jan, 2023
Migraines have low vitamin D, Migraines plus Restless Leg have far lower vitamin D (no surprise) – Dec 2021 07 Dec, 2021
Migraine Headache association with poor gut – Feb 2020 25 Feb, 2021
Migraine headaches treated by Vitamin D – meta-analysis Jan 2021 16 Jan, 2021
Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015 14 Jan, 2021
Why Do Multiple Sclerosis and Migraine Coexist – Jan 2020 28 Jan, 2020
Migraines in youths with low Vitamin D wonderfully treated by Vitamin D – June 2019 12 Jul, 2019
Migraines may be due to lack of lack of Magnesium in half of sufferers – May 2012 25 Oct, 2018
Migraine headache 5X less likely if optimal level of vitamin D – Oct 2018 21 Oct, 2018
Migraine headaches cut in half by 4,000 IU of vitamin D – RCT Sept 2018 06 Sep, 2018
Chronic migraine headaches 1.4 X more likely with low vitamin D – July 2018 05 Jul, 2018
Migraines double the risk of strokes (both are associated with low vitamin D) – Jan 2018 01 Feb, 2018
Vitamin D and Migraine – Nov 2010 06 Sep, 2016
Acute Migraine 35 times more likely if low Magnesium levels – May 2016 12 Jun, 2016
Migraine headaches quickly reduced with Magnesium – Meta-analysis Jan 2016 02 Jun, 2016
Childhood migraine in Vitamin D deficient children reduced 6X by addition of daily 5,000 IU and amitriptyline – April 2014 03 Mar, 2015
Migraine in children reduced with vitamin D supplementation – April 2014 10 Apr, 2014
Migraine more common with high vitamin D, perhaps because of low Magnesium – March 2013 04 Aug, 2013
Migraine headaches associated with low vitamin D, 4,000 IU often helps – review Aug 2019 No value for 'modification_date_major'

VitaminDWiki - both categories Headache and Magnesium

This list is automatically updated

See on web: Headaches and Magnesium: Mechanisms, Bioavailability, Therapeutic Efficacy and Potential Advantage of Magnesium Pidolate - 2022 -10.3390/nu12092660 FREE PDF


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