UV provides the best explanation of COVID-19 variation in Italy (74 pcnt) – Nov 2020

Does solar ultraviolet radiation play a role in COVID-19 infection and deaths? An environmental ecological study in Italy

Sci Total Environ. 2020 Nov 20;143757. doi: 10.1016/j.scitotenv.2020.143757
Giancarlo Isaia 1, Henri Diémoz 2, Francesco Maluta 3, Ilias Fountoulakis 2, Daniela Ceccon 4, Alcide di Sarra 5, Stefania Facta 6, Francesca Fedele 7, Giuseppe Lorenzetto 8, Anna Maria Siani 9, Gianluca Isaia 10

 Download the PDF from VitaminDWiki

NHR = Nursing Home Residents

COVID-19 deaths vs UV

A significantly stronger impact in mortality and morbidity by COVID-19 has been observed in the northern Italian regions compared to the southern ones. The reasons of this geographical pattern might involve several concurrent factors. The main objective of this work is to investigate whether any correlations exist between the spatial distribution of COVID-19 cases and deaths in the different Italian regions and the amount of solar ultraviolet (UV) radiation at the Earth's surface. To this purpose, in this environmental ecological study a mixed-effect exponential regression was built to explain the incidence of COVID-19 based on the environmental conditions, and demographic and pathophysiologic factors. Observations and estimates of the cumulative solar UV exposure have been included to quantify the amount of radiation available e.g., for pre-vitamin D3 synthesis or SARS-CoV-2 inactivation by sunlight. The analysis shows a significant correlation (p-value <5 × 10-2) between the response variables (death percentage, incidence of infections and positive tests) and biologically effective solar UV radiation, residents in nursing homes per inhabitant (NHR), air temperature, death percentage due to the most frequent comorbidities. Among all factors, the amount of solar UV radiation is the variable contributing the most to the observed correlation, explaining up to 83.2% of the variance of the COVID-19 affected cases per population. While the statistical outcomes of the study do not directly entail a specific cause-effect relationship, our results are consistent with the hypothesis that solar UV radiation impacted on the development of the infection and on its complications, e.g. through the effect of vitamin D on the immune system or virus inactivation by sunlight. The analytical framework used in this study, based on commonly available data, can be easily replicated in other countries and geographical domains to identify possible correlations between exposure to solar UV radiation and the spread of the pandemic.

---

List of 50 most-recent Virus pages in VitaminDWiki

• Vitamin D, COVID - Campbell and Davies (UK with transcript) - Jan 18, 2021
• Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
• .Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
• Vitamin D to prevent COVID- strange trial recommendations from the UK – Jan 2021
• 400,000 COVID deaths, 400,000 IUs of Vitamin D needed to prevent COVID death - Jan 2021
• Many COVID-19 risks are associated with low vitamin D (7 studies) – Systematic Review Jan 2021
• 40 ng of Vitamin D to fight COVID 15K to 50K weekly or 100K monthly – Spanish Jan 2021
• Herd immunity occurs only via vaccination - W.H.O. Oct 2020
• Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
• 4X fewer COVID-19 deaths in those having high Omega-3 index – Jan 6, 2021
• COVID-19 cases in Delhi increased 7 days after pollution (less UV and Vitamin D, indoors more) Jan 12, 2021
• Active vitamin D (calcitriol) might fight COVID-19 – Jan 5, 2021
• Many increased risks for dying of COVID-19 in nursing home (Vitamin D not even mentioned) - Jan 6 2021
• Vitamin D sales up 40 percent in Dec (2020 vs 2019)
• 30 x fewer COVID-19 deaths in those getting 400,000 IU of Vitamin D - Jan 2021
• 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
• COVID-19 Disease and Vitamin D: A Mini-Review – Dec 15, 2020
• 6 months after COVID-19 hospitalization 76 percent still had at least one symptom – Jan 8, 2021
• Small study found Vitamin D did not fight COVID-19 (probably mostly less than 30 ng) – Jan 2020
• COVID-19 test positive 4.5 X more likely if had low vitamin D test within 4 years – Jan 6, 2021
• Don’t Let COVID-19 Patients Die With Vitamin D Deficiency - Jan 5, 2021
• Less likely to test positive for COVID-19 if higher Vitamin D – meta-analysis Jan 6, 2021
• Vitamin D reduces COVID-19 by 80 percent - anonymous meta-analysis - Jan 5, 2021
• COVID 19 Video - Drs. Seheult and Campbell : Lessons Learned and a Look Ahead - Jan 4
• Many drugs increase ACE2 and COVID-19 (176 page review) - Dec 2020
• Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
• 400 IU Vitamin D for UK adults with COVID is based on a RTI study biased by infants - Jan 2021
• COVID-19 lung infection upsets Vitamin D genes (so more or different form of Vit D is required) - Dec 22, 2020
• French Consensus – 200,000 IU of Vitamin D if get COVID-19 – Dec 22, 2020
• CDC listed health problems at increased risk of COVID-19 (all are associated with low Vitamin D) - Dec 1, 2020
• The FDA should consider vitamin D as a pharmaceutical agent for COVID - Dec 21, 2020
• Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
• 600,000 IU of Vitamin D (total) allowed previously weak immune systems to fight off a virus antigen - Nov 2020
• Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination
• Yet another low Vitamin D health problem with increased COVID-19 risks (Vertebral Fracture) – Oct 2020
• Rational approach to COVID-19: 50k-100k of Vitamin D weekly – Dec 2020
• Ways to boost immune system to fight COVID-19 (no protocol) - Oct 2020
• Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
• Why Vitamin D is better than the Flu Vaccine – Nov 2018
• Vaccinated children had greatly increased office visits for 14 health problems - Nov 2020
• COVID-19 plus pneumonia in ICU with low vitamin D equaled Death - Dec 2020
• Excellent on-going analysis of Vitamin D and COVID-19 publications
• 7X less likely to die of COVID-19 if taking Vitamin D loading dose – Dec 11, 2020
• COVID-19 patients with low vitamin D had far fewer natural killer cells – Dec 2020
• COVID-19 Vitamin D: Overview by Dr. in Sri Lanka (Video and transcript) - Dec 8, 2020
• COVID-19 Vitamin D: Overview of Evidence by Dr. Seheult (Video and transcript) - Dec 10, 2020
• Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
• 75 articles indicate that Vitamin D should fight COVID-19 – Evidence Review Dec 10, 2020
• 3.8 X higher risk of COVID-19 death if low vitamin D – Belgium Nov 25, 2020
• Vitamin D recommended to fight COVID-19 by 2 groups – Dec 7, 2020